Gene: ENSMUSG00000041241 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000041241
Transcript Identifier
ENSMUST00000044058
Gene Type
Coding gene
Location
4 : 138434760-138439680 : positive

Family Information

Homologous gene family
HOM03P023734
(3 genes in 3 species)
specific family

Descriptions

gene_descr
mitochondrial ubiquitin ligase activator of NFKB 1

Identifiers

Type Value
UniprotQ8VCM5
MGI1915600

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000266
ISS, ISO
IEA
Genome Projectmitochondrial fission
GO:0006915
IEA
Genome Projectapoptotic process
GO:0006919
ISS, ISO
IEA
Genome Projectactivation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007005
IEA
Genome Projectmitochondrion organization
GO:0007257
ISS, ISO
IEA
Genome Projectactivation of JUN kinase activity
GO:0010637
ISO
IEA
Genome Projectnegative regulation of mitochondrial fusion
GO:0010821
ISO
IEA
Genome Projectregulation of mitochondrion organization
GO:0016567
ISS, ISO
IEA
Genome Projectprotein ubiquitination
GO:0016925
IEA
Genome Projectprotein sumoylation
GO:0030308
ISS, ISO
IEA
Genome Projectnegative regulation of cell growth
GO:0031647
IMP
Genome Projectregulation of protein stability
GO:0031648
ISO
IEA
Genome Projectprotein destabilization
GO:0033235
ISO
IEA
Genome Projectpositive regulation of protein sumoylation
GO:0043123
ISS, ISO
IEA
Genome Projectpositive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045824
ISS, ISO
IEA
Genome Projectnegative regulation of innate immune response
GO:0050689
ISS, ISO
IEA
Genome Projectnegative regulation of defense response to virus by host
GO:0050821
ISO
IEA
Genome Projectprotein stabilization
GO:0051646
ISS, ISO
IEA
Genome Projectmitochondrion localization
GO:0051881
IGI
Genome Projectregulation of mitochondrial membrane potential
GO:0051898
ISS, ISO
IEA
Genome Projectnegative regulation of protein kinase B signaling
GO:0060339
ISS, ISO
IEA
Genome Projectnegative regulation of type I interferon-mediated signaling pathway
GO:0071360
ISS, ISO
IEA
Genome Projectcellular response to exogenous dsRNA
GO:0071650
ISS, ISO
IEA
Genome Projectnegative regulation of chemokine (C-C motif) ligand 5 production
GO:0090141
ISO
IEA
Genome Projectpositive regulation of mitochondrial fission
GO:1901028
ISS, ISO
IEA
Genome Projectregulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
GO:1903861
IMP, IGI
Genome Projectpositive regulation of dendrite extension

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004842
ISS, ISO
IEA
Genome Projectubiquitin-protein transferase activity
GO:0004871
ISS, ISO
IEA
Genome Projectsignal transducer activity
GO:0008270
IEA
Genome Projectzinc ion binding
GO:0016874
IEA
Genome Projectligase activity
GO:0019789
ISO
IEA
Genome ProjectSUMO transferase activity
GO:0031625
ISO
IEA
Genome Projectubiquitin protein ligase binding
GO:0042802
ISS, ISO
IEA
Genome Projectidentical protein binding
GO:0046872
IEA
Genome Projectmetal ion binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005654
ISO
IEA
Genome Projectnucleoplasm
GO:0005737
ISO
IEA
Genome Projectcytoplasm
GO:0005739
IDA
ISO
IEA
Genome Projectmitochondrion
GO:0005741
IEA
Genome Projectmitochondrial outer membrane
GO:0005777
ISS, ISO
IEA
Genome Projectperoxisome
GO:0016020
ISO
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0030424
ISO
IEA
Genome Projectaxon
GO:0031307
ISS, ISO
IEA
Genome Projectintegral component of mitochondrial outer membrane
GO:0043025
ISO
IEA
Genome Projectneuronal cell body

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001841Zinc finger, RING-type
IPR013083Zinc finger, RING/FYVE/PHD-type
IPR022170Mitochondrial ubiquitin ligase activator of NFKB 1

No MapMan annotations defined for this gene.