Gene: ENSMUSG00000041238 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000041238
Transcript Identifier
ENSMUST00000047322
Gene Type
Coding gene
Location
18 : 11660833-11742713 : positive

Family Information

Homologous gene family
HOM03P013770
(6 genes in 6 species)
specific family

Descriptions

gene_descr
retinoblastoma binding protein 8

Identifiers

Type Value
UniprotQ80YR6
MGI2442995

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000077
IEA
Genome ProjectDNA damage checkpoint
GO:0000082
IMP
Genome ProjectG1/S transition of mitotic cell cycle
GO:0000122
ISO
IEA
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0000724
ISS, ISO
IEA
Genome Projectdouble-strand break repair via homologous recombination
GO:0000737
IEA
Genome ProjectDNA catabolic process, endonucleolytic
GO:0001835
IMP
Genome Projectblastocyst hatching
GO:0006281
IEA
Genome ProjectDNA repair
GO:0006289
ISO
IEA
Genome Projectnucleotide-excision repair
GO:0006974
IEA
Genome Projectcellular response to DNA damage stimulus
GO:0007049
IEA
Genome Projectcell cycle
GO:0007067
IEA
Genome Projectmitotic nuclear division
GO:0010792
ISO
IEA
Genome ProjectDNA double-strand break processing involved in repair via single-strand annealing
GO:0031572
ISS
IEA
Genome ProjectG2 DNA damage checkpoint
GO:0032355
IEA
Genome Projectresponse to estradiol
GO:0051301
IEA
Genome Projectcell division
GO:0051321
IEA
Genome Projectmeiotic cell cycle

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000014
ISO
IEA
Genome Projectsingle-stranded DNA endodeoxyribonuclease activity
GO:0001103
ISO
IEA
Genome ProjectRNA polymerase II repressing transcription factor binding
GO:0001106
ISO
IEA
Genome ProjectRNA polymerase II transcription corepressor activity
GO:0003677
IEA
Genome ProjectDNA binding
GO:0003684
ISO
IEA
Genome Projectdamaged DNA binding
GO:0004518
IEA
Genome Projectnuclease activity
GO:0004519
IEA
Genome Projectendonuclease activity
GO:0016787
IEA
Genome Projecthydrolase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IEA
Genome Projectnucleus
GO:0005654
ISO
IEA
Genome Projectnucleoplasm
GO:0005730
ISO
IEA
Genome Projectnucleolus
GO:0017053
ISO
IEA
Genome Projecttranscriptional repressor complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR013882Com1/Ctip family
IPR019518Tumour-suppressor protein CtIP N-terminal

No MapMan annotations defined for this gene.