Gene: ENSMUSG00000041187 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000041187
Transcript Identifier
ENSMUST00000086104
Gene Type
Coding gene
Location
7 : 16843624-16870023 : positive

Family Information

Homologous gene family
HOM03P000001
(4368 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P012084
(7 genes in 3 species)
specific family

Descriptions

gene_descr
protein kinase D2

Identifiers

Type Value
UniprotQ8BZ03
MGI2141917

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001525
IEA
Genome Projectangiogenesis
GO:0001938
ISS, ISO
IEA
Genome Projectpositive regulation of endothelial cell proliferation
GO:0002250
IEA
Genome Projectadaptive immune response
GO:0002376
IEA
Genome Projectimmune system process
GO:0006468
ISO
IEA
Genome Projectprotein phosphorylation
GO:0007155
IEA
Genome Projectcell adhesion
GO:0008219
ISO
IEA
Genome Projectcell death
GO:0010595
ISS, ISO
IEA
Genome Projectpositive regulation of endothelial cell migration
GO:0016310
IEA
Genome Projectphosphorylation
GO:0018105
ISO
IEA
Genome Projectpeptidyl-serine phosphorylation
GO:0030949
ISS, ISO
IEA
Genome Projectpositive regulation of vascular endothelial growth factor receptor signaling pathway
GO:0032743
IMP
Genome Projectpositive regulation of interleukin-2 production
GO:0032757
ISS, ISO
IEA
Genome Projectpositive regulation of interleukin-8 production
GO:0032793
ISO
IEA
Genome Projectpositive regulation of CREB transcription factor activity
GO:0033138
ISO
IEA
Genome Projectpositive regulation of peptidyl-serine phosphorylation
GO:0035556
ISO
IEA
Genome Projectintracellular signal transduction
GO:0035924
ISO
IEA
Genome Projectcellular response to vascular endothelial growth factor stimulus
GO:0038033
ISO
IEA
Genome Projectpositive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway
GO:0043536
ISO
IEA
Genome Projectpositive regulation of blood vessel endothelial cell migration
GO:0045743
ISS, ISO
IEA
Genome Projectpositive regulation of fibroblast growth factor receptor signaling pathway
GO:0045766
ISS, ISO
IEA
Genome Projectpositive regulation of angiogenesis
GO:0045785
ISS, ISO
IEA
Genome Projectpositive regulation of cell adhesion
GO:0045944
ISO
IEA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0046777
ISO
IEA
Genome Projectprotein autophosphorylation
GO:0048010
ISO
IEA
Genome Projectvascular endothelial growth factor receptor signaling pathway
GO:0050852
ISO
IEA
Genome ProjectT cell receptor signaling pathway
GO:0050862
IMP
Genome Projectpositive regulation of T cell receptor signaling pathway
GO:0051091
ISS, ISO
IEA
Genome Projectpositive regulation of sequence-specific DNA binding transcription factor activity
GO:0051092
ISS, ISO
IEA
Genome Projectpositive regulation of NF-kappaB transcription factor activity
GO:0070374
IDA
Genome Projectpositive regulation of ERK1 and ERK2 cascade
GO:0089700
ISO
IEA
Genome Projectprotein kinase D signaling
GO:0098779
ISO
Genome Projectmitophagy in response to mitochondrial depolarization
GO:1901727
ISO
IEA
Genome Projectpositive regulation of histone deacetylase activity
GO:1902533
ISO
IEA
Genome Projectpositive regulation of intracellular signal transduction
GO:1903146
IEA
Genome Projectregulation of mitophagy
GO:2000573
IDA
Genome Projectpositive regulation of DNA biosynthetic process
GO:2001028
ISO
IEA
Genome Projectpositive regulation of endothelial cell chemotaxis

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0004672
ISO
IEA
Genome Projectprotein kinase activity
GO:0004674
ISO
IEA
Genome Projectprotein serine/threonine kinase activity
GO:0004697
IEA
Genome Projectprotein kinase C activity
GO:0005524
IEA
Genome ProjectATP binding
GO:0016301
IEA
Genome Projectkinase activity
GO:0016740
IEA
Genome Projecttransferase activity
GO:0046872
IEA
Genome Projectmetal ion binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
ISO
IEA
Genome Projectnucleus
GO:0005654
ISO
IEA
Genome Projectnucleoplasm
GO:0005737
ISO
IEA
Genome Projectcytoplasm
GO:0005794
IEA
Genome ProjectGolgi apparatus
GO:0005886
IEA
Genome Projectplasma membrane
GO:0016020
IEA
Genome Projectmembrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000719Protein kinase domain
IPR001849Pleckstrin homology domain
IPR002219Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
IPR002290Serine/threonine/dual specificity protein kinase, catalytic domain
IPR008271Serine/threonine-protein kinase, active site
IPR011009Protein kinase-like domain
IPR011993PH domain-like
IPR015727Protein kinase C mu-related
IPR017441Protein kinase, ATP binding site
IPR020454Diacylglycerol/phorbol-ester binding

No MapMan annotations defined for this gene.