Gene: ENSMUSG00000040021 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000040021
Transcript Identifier
ENSMUST00000040043
Gene Type
Coding gene
Location
10 : 7691467-7713010 : positive

Family Information

Homologous gene family
HOM03P000015
(1237 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P034424
(3 genes in 2 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
large tumor suppressor

Identifiers

Type Value
UniprotQ8BYR2
MGI1333883

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000086
ISS, ISO
IEA
Genome ProjectG2/M transition of mitotic cell cycle
GO:0000819
ISS, ISO
IEA
Genome Projectsister chromatid segregation
GO:0006468
ISS, ISO
IEA
Genome Projectprotein phosphorylation
GO:0007049
IEA
Genome Projectcell cycle
GO:0007067
IEA
Genome Projectmitotic nuclear division
GO:0009755
IDA
Genome Projecthormone-mediated signaling pathway
GO:0016310
IEA
Genome Projectphosphorylation
GO:0030216
IGI
Genome Projectkeratinocyte differentiation
GO:0030833
ISS, ISO
IEA
Genome Projectregulation of actin filament polymerization
GO:0033138
ISO
IEA
Genome Projectpositive regulation of peptidyl-serine phosphorylation
GO:0034613
IGI
Genome Projectcellular protein localization
GO:0035329
IGI
ISO
IEA
Genome Projecthippo signaling
GO:0043254
ISO
IEA
Genome Projectregulation of protein complex assembly
GO:0045736
ISS, ISO
IEA
Genome Projectnegative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0051220
ISO
IEA
Genome Projectcytoplasmic sequestering of protein
GO:0051301
IEA
Genome Projectcell division
GO:0090090
ISO
IEA
Genome Projectnegative regulation of canonical Wnt signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0000287
ISS, ISO
IEA
Genome Projectmagnesium ion binding
GO:0004672
IEA
Genome Projectprotein kinase activity
GO:0004674
ISS, ISO
IEA
Genome Projectprotein serine/threonine kinase activity
GO:0005524
ISS, ISO
IEA
Genome ProjectATP binding
GO:0016301
IEA
Genome Projectkinase activity
GO:0016740
IEA
Genome Projecttransferase activity
GO:0019901
ISO
IEA
Genome Projectprotein kinase binding
GO:0046872
IEA
Genome Projectmetal ion binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000922
ISS, ISO
IEA
Genome Projectspindle pole
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005815
IEA
Genome Projectmicrotubule organizing center
GO:0005819
IEA
Genome Projectspindle
GO:0005856
IEA
Genome Projectcytoskeleton

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000719Protein kinase domain
IPR000961AGC-kinase, C-terminal
IPR002290Serine/threonine/dual specificity protein kinase, catalytic domain
IPR008271Serine/threonine-protein kinase, active site
IPR009060UBA-like
IPR011009Protein kinase-like domain
IPR015940Ubiquitin-associated domain
IPR028741Serine/threonine-protein kinase LATS1/ Warts

No MapMan annotations defined for this gene.