Gene: ENSMUSG00000039521 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000039521
Transcript Identifier
ENSMUST00000045566
Gene Type
Coding gene
Location
X : 7586355-7593043 : positive

Family Information

Homologous gene family
HOM03P008089
(10 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P074432
(2 genes in 2 species)
specific family

Descriptions

gene_descr
forkhead box P3

Identifiers

Type Value
UniprotQ99JB6
UniprotQ53Z59
MGI1891436

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
IDA, IMP
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0001782
IMP
Genome ProjectB cell homeostasis
GO:0001816
IDA, IMP, IGI
Genome Projectcytokine production
GO:0002262
IMP
Genome Projectmyeloid cell homeostasis
GO:0002361
IMP
Genome ProjectCD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
GO:0002456
IMP
Genome ProjectT cell mediated immunity
GO:0002507
IDA
Genome Projecttolerance induction
GO:0002513
IMP
Genome Projecttolerance induction to self antigen
GO:0002637
IMP
Genome Projectregulation of immunoglobulin production
GO:0002666
IMP
Genome Projectpositive regulation of T cell tolerance induction
GO:0002669
IMP
Genome Projectpositive regulation of T cell anergy
GO:0002677
IDA, IMP
Genome Projectnegative regulation of chronic inflammatory response
GO:0002725
ISS, ISO
IEA
Genome Projectnegative regulation of T cell cytokine production
GO:0002851
IMP
Genome Projectpositive regulation of peripheral T cell tolerance induction
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006357
IGI
Genome Projectregulation of transcription from RNA polymerase II promoter
GO:0008285
ISS, ISO
IEA
Genome Projectnegative regulation of cell proliferation
GO:0009615
IEA
Genome Projectresponse to virus
GO:0009653
IBA
Genome Projectanatomical structure morphogenesis
GO:0010628
IDA
Genome Projectpositive regulation of gene expression
GO:0031064
ISO
IEA
Genome Projectnegative regulation of histone deacetylation
GO:0032088
ISS, ISO
IEA
Genome Projectnegative regulation of NF-kappaB transcription factor activity
GO:0032689
IDA, IMP
ISS, ISO
IEA
Genome Projectnegative regulation of interferon-gamma production
GO:0032693
IMP
ISS, ISO
IEA
Genome Projectnegative regulation of interleukin-10 production
GO:0032700
IMP
ISO
IEA
Genome Projectnegative regulation of interleukin-17 production
GO:0032703
IDA, IMP
ISS, ISO
IEA
Genome Projectnegative regulation of interleukin-2 production
GO:0032713
IDA, IMP
ISS, ISO
IEA
Genome Projectnegative regulation of interleukin-4 production
GO:0032714
IDA, IMP
Genome Projectnegative regulation of interleukin-5 production
GO:0032715
IMP
Genome Projectnegative regulation of interleukin-6 production
GO:0032720
IMP
Genome Projectnegative regulation of tumor necrosis factor production
GO:0032753
IMP
Genome Projectpositive regulation of interleukin-4 production
GO:0032792
ISS, ISO
IEA
Genome Projectnegative regulation of CREB transcription factor activity
GO:0032831
IMP
TAS
Genome Projectpositive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
GO:0032914
IDA
Genome Projectpositive regulation of transforming growth factor beta1 production
GO:0033092
IMP
Genome Projectpositive regulation of immature T cell proliferation in thymus
GO:0035066
IDA
ISO
IEA
Genome Projectpositive regulation of histone acetylation
GO:0035067
IDA
Genome Projectnegative regulation of histone acetylation
GO:0042036
ISS, ISO
IEA
Genome Projectnegative regulation of cytokine biosynthetic process
GO:0042110
IMP
ISS, ISO
IEA
Genome ProjectT cell activation
GO:0042130
IDA, IMP
ISS, ISO
IEA
Genome Projectnegative regulation of T cell proliferation
GO:0043433
ISS, ISO
IEA
Genome Projectnegative regulation of sequence-specific DNA binding transcription factor activity
GO:0045066
IDA, IMP
Genome Projectregulatory T cell differentiation
GO:0045077
IDA
Genome Projectnegative regulation of interferon-gamma biosynthetic process
GO:0045085
IDA
ISS, ISO
IEA
Genome Projectnegative regulation of interleukin-2 biosynthetic process
GO:0045591
IDA
Genome Projectpositive regulation of regulatory T cell differentiation
GO:0045892
IDA
ISS, ISO
IEA
Genome Projectnegative regulation of transcription, DNA-templated
GO:0045893
IDA, IMP
ISS, ISO
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045944
IDA, IMP
ISO
IEA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0048294
IMP
Genome Projectnegative regulation of isotype switching to IgE isotypes
GO:0048302
IMP
Genome Projectregulation of isotype switching to IgG isotypes
GO:0050672
IMP
Genome Projectnegative regulation of lymphocyte proliferation
GO:0050710
ISS, ISO
IEA
Genome Projectnegative regulation of cytokine secretion
GO:0050728
IMP
Genome Projectnegative regulation of inflammatory response
GO:0050777
ISS, ISO
IEA
Genome Projectnegative regulation of immune response
GO:0050852
IMP
Genome ProjectT cell receptor signaling pathway
GO:2000320
ISS, ISO
IEA
Genome Projectnegative regulation of T-helper 17 cell differentiation
GO:0002362
TAS
Genome ProjectCD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment
GO:0002667
IMP
Genome Projectregulation of T cell anergy

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003676
IEA
Genome Projectnucleic acid binding
GO:0003677
IEA
Genome ProjectDNA binding
GO:0003700
IDA
ISS, ISO
IEA
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0003705
IDA
Genome Projecttranscription factor activity, RNA polymerase II distal enhancer sequence-specific binding
GO:0003714
IDA
Genome Projecttranscription corepressor activity
GO:0035035
ISO
IEA
Genome Projecthistone acetyltransferase binding
GO:0042803
IDA
ISS, ISO
IEA
Genome Projectprotein homodimerization activity
GO:0042826
ISO
IEA
Genome Projecthistone deacetylase binding
GO:0043565
IDA
ISS, ISO
IEA
Genome Projectsequence-specific DNA binding
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0051525
ISS, ISO
IEA
Genome ProjectNFAT protein binding
GO:0001047
IDA
Genome Projectcore promoter binding
GO:0005515
IPI
Genome Projectprotein binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005622
IDA
Genome Projectintracellular
GO:0005634
IDA
ISS, ISO
IEA
Genome Projectnucleus
GO:0005737
IDA
ISO
IEA
Genome Projectcytoplasm

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001766Fork head domain
IPR007087Zinc finger, C2H2
IPR011991Winged helix-turn-helix DNA-binding domain
IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
IPR015880Zinc finger, C2H2-like
IPR032354FOXP, coiled-coil domain

No MapMan annotations defined for this gene.