Gene: ENSMUSG00000039474 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000039474
Transcript Identifier
ENSMUST00000043964
Gene Type
Coding gene
Location
5 : 36966873-36982292 : negative

Family Information

Homologous gene family
HOM03P038085
(2 genes in 2 species)
specific family

Descriptions

gene_descr
Wolfram syndrome 1 homolog (human)

Identifiers

Type Value
UniprotP56695
UniprotQ3TDI2
MGI1328355

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
ISO
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0001822
ISS, ISO
IEA
Genome Projectkidney development
GO:0003091
ISS, ISO
IEA
Genome Projectrenal water homeostasis
GO:0007601
ISS, ISO
NAS, IEA
Genome Projectvisual perception
GO:0007605
ISS, ISO
IEA
Genome Projectsensory perception of sound
GO:0030433
IMP
ISO
Genome ProjectER-associated ubiquitin-dependent protein catabolic process
GO:0030968
IMP
Genome Projectendoplasmic reticulum unfolded protein response
GO:0031398
IMP
ISO
Genome Projectpositive regulation of protein ubiquitination
GO:0032469
ISS, ISO
IEA
Genome Projectendoplasmic reticulum calcium ion homeostasis
GO:0034976
IDA
ISO
IEA
Genome Projectresponse to endoplasmic reticulum stress
GO:0042593
ISS, ISO
IEA
Genome Projectglucose homeostasis
GO:0043069
ISS, ISO
IEA
Genome Projectnegative regulation of programmed cell death
GO:0043433
ISO
Genome Projectnegative regulation of sequence-specific DNA binding transcription factor activity
GO:0043524
ISS, ISO
IEA
Genome Projectnegative regulation of neuron apoptotic process
GO:0045762
IMP
Genome Projectpositive regulation of adenylate cyclase activity
GO:0045927
IMP
Genome Projectpositive regulation of growth
GO:0050821
IMP
ISO
Genome Projectprotein stabilization
GO:0050877
ISS, ISO
IEA
Genome Projectneurological system process
GO:0051247
ISS, ISO
IEA
Genome Projectpositive regulation of protein metabolic process
GO:0051726
NAS
Genome Projectregulation of cell cycle
GO:0051928
ISS, ISO
IEA
Genome Projectpositive regulation of calcium ion transport
GO:0055074
ISS, ISO
IEA
Genome Projectcalcium ion homeostasis
GO:1902236
IMP
Genome Projectnegative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
GO:1903892
ISO
Genome Projectnegative regulation of ATF6-mediated unfolded protein response
GO:2000675
IMP
ISO
IEA
Genome Projectnegative regulation of type B pancreatic cell apoptotic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0031625
ISO
Genome Projectubiquitin protein ligase binding
GO:0051117
IDA
ISO
IEA
Genome ProjectATPase binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005783
IDA
IEA
Genome Projectendoplasmic reticulum
GO:0005789
IEA
Genome Projectendoplasmic reticulum membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0030176
ISS, ISO
IEA
Genome Projectintegral component of endoplasmic reticulum membrane
GO:0030425
ISS
Genome Projectdendrite

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR026208Wolframin
IPR026209Wolframin family

No MapMan annotations defined for this gene.