Gene: ENSMUSG00000039361 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000039361
Transcript Identifier
ENSMUST00000049537
Gene Type
Coding gene
Location
7 : 90130573-90207597 : positive

Family Information

Homologous gene family
HOM03P000708
(78 genes in 29 species)
specific family
Orthologous gene family
ORTHO03P028885
(4 genes in 4 species)
specific family

Descriptions

gene_descr
phosphatidylinositol binding clathrin assembly protein

Identifiers

Type Value
UniprotQ7M6Y3
MGI2385902

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006897
IEA
Genome Projectendocytosis
GO:0006898
IDA
ISS, ISO
Genome Projectreceptor-mediated endocytosis
GO:0007275
IEA
Genome Projectmulticellular organismal development
GO:0007409
IMP
Genome Projectaxonogenesis
GO:0008283
ISS, ISO
IEA
Genome Projectcell proliferation
GO:0010629
ISS, ISO
IEA
Genome Projectnegative regulation of gene expression
GO:0016188
IMP
Genome Projectsynaptic vesicle maturation
GO:0016197
ISO
IEA
Genome Projectendosomal transport
GO:0030097
IMP
Genome Projecthemopoiesis
GO:0030100
ISO
IEA
Genome Projectregulation of endocytosis
GO:0031623
ISO
IEA
Genome Projectreceptor internalization
GO:0032880
ISO
IEA
Genome Projectregulation of protein localization
GO:0035459
IMP
ISO
IEA
Genome Projectcargo loading into vesicle
GO:0045893
ISO
IEA
Genome Projectpositive regulation of transcription, DNA-templated
GO:0048261
ISO
IEA
Genome Projectnegative regulation of receptor-mediated endocytosis
GO:0048268
ISO
IEA
Genome Projectclathrin coat assembly
GO:0048813
IMP
Genome Projectdendrite morphogenesis
GO:0055072
ISS, ISO
IEA
Genome Projectiron ion homeostasis
GO:0072583
IMP
ISO
IEA
Genome Projectclathrin-mediated endocytosis
GO:0097459
ISS, ISO
IEA
Genome Projectiron ion import into cell
GO:1901216
ISS, ISO
IEA
Genome Projectpositive regulation of neuron death
GO:1902004
IMP
ISO
IEA
Genome Projectpositive regulation of beta-amyloid formation
GO:1902959
ISS, ISO
IEA
Genome Projectregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
GO:1902961
IMP
Genome Projectpositive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
GO:1902963
IMP
Genome Projectnegative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005543
IEA
Genome Projectphospholipid binding
GO:0005545
ISS
IEA
Genome Project1-phosphatidylinositol binding
GO:0030276
ISS, ISO
IEA
Genome Projectclathrin binding
GO:0032050
ISO
IEA
Genome Projectclathrin heavy chain binding
GO:0035615
ISS, ISO
IEA
Genome Projectclathrin adaptor activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005622
IDA
Genome Projectintracellular
GO:0005634
ISO
IEA
Genome Projectnucleus
GO:0005794
IEA
Genome ProjectGolgi apparatus
GO:0005905
IDA
ISS, ISO
IEA
Genome Projectcoated pit
GO:0016020
ISO
IEA
Genome Projectmembrane
GO:0030122
ISO
IEA
Genome ProjectAP-2 adaptor complex
GO:0030132
ISO
IEA
Genome Projectclathrin coat of coated pit
GO:0030136
IEA
Genome Projectclathrin-coated vesicle
GO:0031410
IEA
Genome Projectcytoplasmic vesicle
GO:0031982
IDA
Genome Projectvesicle
GO:0043025
ISS, ISO
IEA
Genome Projectneuronal cell body
GO:0043231
ISO
IEA
Genome Projectintracellular membrane-bounded organelle
GO:0097418
ISS, ISO
IEA
Genome Projectneurofibrillary tangle
GO:0048471
IDA
Genome Projectperinuclear region of cytoplasm

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR008942ENTH/VHS
IPR011417AP180 N-terminal homology (ANTH) domain
IPR013809ENTH domain
IPR014712Phosphoinositide-binding clathrin adaptor, domain 2
IPR030412Phosphatidylinositol-binding clathrin assembly protein

No MapMan annotations defined for this gene.