Gene: ENSMUSG00000039193 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000039193
Transcript Identifier
ENSMUST00000052124
Gene Type
Coding gene
Location
17 : 74426842-74453053 : negative

Family Information

Homologous gene family
HOM03P005043
(18 genes in 5 species)
specific family
Orthologous gene family
ORTHO03P066566
(2 genes in 2 species)
specific family

Descriptions

gene_descr
NLR family, CARD domain containing 4

Identifiers

Type Value
UniprotQ3UP24
MGI3036243

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002218
IMP
Genome Projectactivation of innate immune response
GO:0002376
IEA
Genome Projectimmune system process
GO:0006915
IEA
Genome Projectapoptotic process
GO:0006919
ISS, ISO
IEA
Genome Projectactivation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006954
IMP
IEA
Genome Projectinflammatory response
GO:0009966
IBA
Genome Projectregulation of signal transduction
GO:0016045
IMP
ISS, ISO
IEA
Genome Projectdetection of bacterium
GO:0016567
IBA
Genome Projectprotein ubiquitination
GO:0042742
IMP
ISS, ISO
IEA
Genome Projectdefense response to bacterium
GO:0042981
IMP
IEA
Genome Projectregulation of apoptotic process
GO:0043065
ISO
IEA
Genome Projectpositive regulation of apoptotic process
GO:0043281
IMP
Genome Projectregulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043523
IBA
Genome Projectregulation of neuron apoptotic process
GO:0045087
IEA
Genome Projectinnate immune response
GO:0050702
IMP
ISS, ISO
IEA
Genome Projectinterleukin-1 beta secretion
GO:0051092
ISO
IEA
Genome Projectpositive regulation of NF-kappaB transcription factor activity
GO:0051260
IDA
Genome Projectprotein homooligomerization
GO:0070269
IMP
Genome Projectpyroptosis
GO:0090307
IBA
Genome Projectmitotic spindle assembly
GO:1990001
IBA
Genome Projectinhibition of cysteine-type endopeptidase activity involved in apoptotic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0004842
IBA
Genome Projectubiquitin-protein transferase activity
GO:0004869
IBA
Genome Projectcysteine-type endopeptidase inhibitor activity
GO:0005524
ISS, ISO
IEA
Genome ProjectATP binding
GO:0042802
ISO
IEA
Genome Projectidentical protein binding
GO:0042803
ISS, ISO
IEA
Genome Projectprotein homodimerization activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IBA
Genome Projectnucleus
GO:0005737
IBA
IEA
Genome Projectcytoplasm
GO:0005829
IDA
TAS, IEA
Genome Projectcytosol
GO:0005876
IBA
Genome Projectspindle microtubule
GO:0072557
IDA
Genome ProjectIPAF inflammasome complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001315CARD domain
IPR007111NACHT nucleoside triphosphatase
IPR011029Death-like domain
IPR027417P-loop containing nucleoside triphosphate hydrolase

No MapMan annotations defined for this gene.