Gene: ENSMUSG00000038612 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000038612
Transcript Identifier
ENSMUST00000037947
Gene Type
Coding gene
Location
3 : 95658857-95660823 : positive

Family Information

Homologous gene family
HOM03P039085
(2 genes in 2 species)
specific family

Descriptions

gene_descr
myeloid cell leukemia sequence 1

Identifiers

Type Value
UniprotP97287
MGI101769

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006915
IEA
Genome Projectapoptotic process
GO:0007275
IEA
Genome Projectmulticellular organismal development
GO:0008630
IDA
Genome Projectintrinsic apoptotic signaling pathway in response to DNA damage
GO:0008637
IDA
Genome Projectapoptotic mitochondrial changes
GO:0030154
IEA
Genome Projectcell differentiation
GO:0034097
ISO
IEA
Genome Projectresponse to cytokine
GO:0042981
IEA
Genome Projectregulation of apoptotic process
GO:0043066
IMP
Genome Projectnegative regulation of apoptotic process
GO:0097192
IMP
ISO
IEA
Genome Projectextrinsic apoptotic signaling pathway in absence of ligand
GO:1903378
IMP
ISO
IEA
Genome Projectpositive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
GO:2000811
ISO
IEA
Genome Projectnegative regulation of anoikis
GO:2001020
ISO
IEA
Genome Projectregulation of response to DNA damage stimulus
GO:2001240
ISO
IEA
Genome Projectnegative regulation of extrinsic apoptotic signaling pathway in absence of ligand
GO:2001243
IBA
Genome Projectnegative regulation of intrinsic apoptotic signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005515
IPI
Genome Projectprotein binding
GO:0042803
IBA
Genome Projectprotein homodimerization activity
GO:0046982
ISO, IBA
IEA
Genome Projectprotein heterodimerization activity
GO:0051434
IPI
ISO
IEA
Genome ProjectBH3 domain binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
ISO
IEA
Genome Projectnucleus
GO:0005654
IEA
Genome Projectnucleoplasm
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0005739
IDA
ISO
IEA
Genome Projectmitochondrion
GO:0005741
IBA
Genome Projectmitochondrial outer membrane
GO:0005759
IDA
Genome Projectmitochondrial matrix
GO:0005829
IDA
Genome Projectcytosol
GO:0016020
IDA
ISO
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0097136
ISO
IEA
Genome ProjectBcl-2 family protein complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR002475Bcl2-like
IPR013281Apoptosis regulator, Mcl-1
IPR020717Apoptosis regulator, Bcl-2, BH1 motif, conserved site
IPR020726Apoptosis regulator, Bcl-2, BH2 motif, conserved site
IPR020728Apoptosis regulator, Bcl-2, BH3 motif, conserved site
IPR026298Blc2 family

No MapMan annotations defined for this gene.