Gene: ENSMUSG00000037295 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000037295
Transcript Identifier
ENSMUST00000037828
Gene Type
Coding gene
Location
4 : 134747052-134767900 : negative

Family Information

Homologous gene family
HOM03P031877
(2 genes in 2 species)
specific family

Descriptions

gene_descr
low density lipoprotein receptor adaptor protein 1

Identifiers

Type Value
UniprotQ8C142
MGI2140175

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006629
IEA
Genome Projectlipid metabolic process
GO:0006897
IEA
Genome Projectendocytosis
GO:0006898
ISO
IEA
Genome Projectreceptor-mediated endocytosis
GO:0008202
IEA
Genome Projectsteroid metabolic process
GO:0008203
IEA
Genome Projectcholesterol metabolic process
GO:0009967
ISO
IEA
Genome Projectpositive regulation of signal transduction
GO:0031623
ISO
IEA
Genome Projectreceptor internalization
GO:0042632
IMP
ISO
IEA
Genome Projectcholesterol homeostasis
GO:0042982
ISO
IEA
Genome Projectamyloid precursor protein metabolic process
GO:0043393
ISO
IEA
Genome Projectregulation of protein binding
GO:0048260
ISS, ISO
IEA
Genome Projectpositive regulation of receptor-mediated endocytosis
GO:0090003
ISO
IEA
Genome Projectregulation of establishment of protein localization to plasma membrane
GO:0090118
ISO
IEA
Genome Projectreceptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001540
IPI
ISO
IEA
Genome Projectbeta-amyloid binding
GO:0001784
ISS, ISO
IEA
Genome Projectphosphotyrosine binding
GO:0005102
ISA
Genome Projectreceptor binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0005546
ISO
IEA
Genome Projectphosphatidylinositol-4,5-bisphosphate binding
GO:0030159
ISO
IEA
Genome Projectreceptor signaling complex scaffold activity
GO:0030276
ISS, ISO, ISA
IEA
Genome Projectclathrin binding
GO:0035591
ISO
IEA
Genome Projectsignaling adaptor activity
GO:0035612
ISO
IEA
Genome ProjectAP-2 adaptor complex binding
GO:0035615
ISO
IEA
Genome Projectclathrin adaptor activity
GO:0050750
ISO
IEA
Genome Projectlow-density lipoprotein particle receptor binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0005769
IDA
ISO
IEA
Genome Projectearly endosome
GO:0005829
ISS, ISO
IEA
Genome Projectcytosol
GO:0005883
IDA
Genome Projectneurofilament
GO:0009898
ISO
IEA
Genome Projectcytoplasmic side of plasma membrane
GO:0009925
ISS, ISO
IEA
Genome Projectbasal plasma membrane
GO:0030121
ISS, ISO
IEA
Genome ProjectAP-1 adaptor complex
GO:0030122
ISS, ISO
IEA
Genome ProjectAP-2 adaptor complex
GO:0030424
IEA
Genome Projectaxon
GO:0055037
ISO
IEA
Genome Projectrecycling endosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR006020PTB/PI domain
IPR011993PH domain-like

No MapMan annotations defined for this gene.