Pico-PLAZA 3.0 gene overview : ENSMUSG00000036986

Gene: ENSMUSG00000036986 (Mus musculus)

Overview

Gene Identifier: ENSMUSG00000036986
Transcript Identifier: ENSMUST00000085673
Gene Type: Coding gene
Location: 9 : 58219803-58249690 : negative

Family Information

Homologous gene family: HOM03P034492
(2 genes in 2 species)
specific family

Descriptions

gene_descr: promyelocytic leukemia

Identifiers

Type	Value
Uniprot	Q60953
Uniprot	A0A068EW80
MGI	104662

Toolbox

Biological Process

GO term	Evidence(s)	Provider(s)	Description
GO:0001666	IMP ISS, ISO IEA	Genome Project	response to hypoxia
GO:0002230	ISO IEA	Genome Project	positive regulation of defense response to virus by host
GO:0006355	IDA ISO IEA	Genome Project	regulation of transcription, DNA-templated
GO:0006461	ISS, ISO IEA	Genome Project	protein complex assembly
GO:0006605	ISS, ISO IEA	Genome Project	protein targeting
GO:0006915	ISO IEA	Genome Project	apoptotic process
GO:0006919	IMP	Genome Project	activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007050	IMP ISO IEA	Genome Project	cell cycle arrest
GO:0007179	IMP	Genome Project	transforming growth factor beta receptor signaling pathway
GO:0007182	IMP	Genome Project	common-partner SMAD protein phosphorylation
GO:0007184	IMP	Genome Project	SMAD protein import into nucleus
GO:0008285	IMP ISO IEA	Genome Project	negative regulation of cell proliferation
GO:0008630	IMP ISO IEA	Genome Project	intrinsic apoptotic signaling pathway in response to DNA damage
GO:0008631	IMP	Genome Project	intrinsic apoptotic signaling pathway in response to oxidative stress
GO:0009411	IMP	Genome Project	response to UV
GO:0010332	IMP	Genome Project	response to gamma radiation
GO:0016525	IMP ISS, ISO IEA	Genome Project	negative regulation of angiogenesis
GO:0030099	IMP	Genome Project	myeloid cell differentiation
GO:0030308	ISS, ISO IEA	Genome Project	negative regulation of cell growth
GO:0030578	IDA ISO IEA	Genome Project	PML body organization
GO:0031065	ISS, ISO IEA	Genome Project	positive regulation of histone deacetylation
GO:0032211	ISO IEA	Genome Project	negative regulation of telomere maintenance via telomerase
GO:0032938	ISO IEA	Genome Project	negative regulation of translation in response to oxidative stress
GO:0034097	ISO IEA	Genome Project	response to cytokine
GO:0043161	ISS, ISO IEA	Genome Project	proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0045087	IDA ISO IEA	Genome Project	innate immune response
GO:0045165	IMP	Genome Project	cell fate commitment
GO:0045892	ISS, ISO IEA	Genome Project	negative regulation of transcription, DNA-templated
GO:0045930	ISO IEA	Genome Project	negative regulation of mitotic cell cycle
GO:0048384	IMP	Genome Project	retinoic acid receptor signaling pathway
GO:0050821	ISO IEA	Genome Project	protein stabilization
GO:0051457	ISO IEA	Genome Project	maintenance of protein location in nucleus
GO:0051974	ISO IEA	Genome Project	negative regulation of telomerase activity
GO:0060058	ISO IEA	Genome Project	positive regulation of apoptotic process involved in mammary gland involution
GO:0060444	IMP	Genome Project	branching involved in mammary gland duct morphogenesis
GO:0070059	IMP	Genome Project	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0071353	IDA	Genome Project	cellular response to interleukin-4
GO:0072332	IMP	Genome Project	intrinsic apoptotic signaling pathway by p53 class mediator
GO:0090398	ISS, ISO IEA	Genome Project	cellular senescence
GO:0097191	IMP	Genome Project	extrinsic apoptotic signaling pathway
GO:1902187	IDA ISO IEA	Genome Project	negative regulation of viral release from host cell
GO:2000059	ISO IEA	Genome Project	negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:2000779	ISS, ISO IEA	Genome Project	regulation of double-strand break repair
GO:2001235	IMP, IGI	Genome Project	positive regulation of apoptotic signaling pathway
GO:2001238	ISO IEA	Genome Project	positive regulation of extrinsic apoptotic signaling pathway
GO:0001932	IMP	Genome Project	regulation of protein phosphorylation
GO:0002376	IEA	Genome Project	immune system process
GO:0006351	IEA	Genome Project	transcription, DNA-templated
GO:0006977	IMP	Genome Project	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0007569	IMP	Genome Project	cell aging
GO:0010522	IMP	Genome Project	regulation of calcium ion transport into cytosol
GO:0010761	IMP	Genome Project	fibroblast migration
GO:0016032	IEA	Genome Project	viral process
GO:0030155	IMP	Genome Project	regulation of cell adhesion
GO:0032469	IMP	Genome Project	endoplasmic reticulum calcium ion homeostasis
GO:0032922	IDA	Genome Project	circadian regulation of gene expression
GO:0042752	IDA	Genome Project	regulation of circadian rhythm
GO:0042771	IMP	Genome Project	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0043153	IDA	Genome Project	entrainment of circadian clock by photoperiod
GO:0045343	IDA	Genome Project	regulation of MHC class I biosynthetic process
GO:0048146	IMP	Genome Project	positive regulation of fibroblast proliferation
GO:0048511	IEA	Genome Project	rhythmic process
GO:0050711	IMP	Genome Project	negative regulation of interleukin-1 secretion
GO:0050713	IMP	Genome Project	negative regulation of interleukin-1 beta secretion
GO:0051607	IEA	Genome Project	defense response to virus

Molecular Function

GO term	Evidence(s)	Provider(s)	Description
GO:0003713	ISO TAS, IEA	Genome Project	transcription coactivator activity
GO:0005515	IPI	Genome Project	protein binding
GO:0008270	ISO IEA	Genome Project	zinc ion binding
GO:0031625	ISO IEA	Genome Project	ubiquitin protein ligase binding
GO:0032183	ISO IEA	Genome Project	SUMO binding
GO:0042803	ISO IEA	Genome Project	protein homodimerization activity
GO:0046332	IDA	Genome Project	SMAD binding
GO:0046872	IEA	Genome Project	metal ion binding
GO:0046982	ISO IEA	Genome Project	protein heterodimerization activity
GO:0050897	ISO IEA	Genome Project	cobalt ion binding
GO:0003677	IEA	Genome Project	DNA binding

Cellular Component

GO term	Evidence(s)	Provider(s)	Description
GO:0005622	IEA	Genome Project	intracellular
GO:0005634	IDA ISO IEA	Genome Project	nucleus
GO:0005654	ISS, ISO IEA	Genome Project	nucleoplasm
GO:0005730	ISS, ISO IEA	Genome Project	nucleolus
GO:0005737	ISO IEA	Genome Project	cytoplasm
GO:0016363	IDA ISO IEA	Genome Project	nuclear matrix
GO:0016605	IDA, IMP ISS, ISO IEA	Genome Project	PML body
GO:0031965	ISO IEA	Genome Project	nuclear membrane
GO:0005768	IEA	Genome Project	endosome
GO:0005783	IEA	Genome Project	endoplasmic reticulum
GO:0005789	IEA	Genome Project	endoplasmic reticulum membrane
GO:0005829	IDA	Genome Project	cytosol
GO:0016020	IEA	Genome Project	membrane
GO:0031901	IEA	Genome Project	early endosome membrane
GO:0042406	IDA	Genome Project	extrinsic component of endoplasmic reticulum membrane

Color Legend

Experimental Evidence

Computational Reviewed Evidence

Electronic Evidence

InterPro	Description
IPR000315	B-box-type zinc finger
IPR001841	Zinc finger, RING-type
IPR013083	Zinc finger, RING/FYVE/PHD-type
IPR017907	Zinc finger, RING-type, conserved site
IPR021978	Protein of unknown function DUF3583

No MapMan annotations defined for this gene.

Gene: ENSMUSG00000036986 (Mus musculus)

Overview

Family Information

Descriptions

Identifiers

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Biological Process

Molecular Function

Cellular Component

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