Gene: ENSMUSG00000036986 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000036986
Transcript Identifier
ENSMUST00000085673
Gene Type
Coding gene
Location
9 : 58219803-58249690 : negative

Family Information

Homologous gene family
HOM03P034492
(2 genes in 2 species)
specific family

Descriptions

gene_descr
promyelocytic leukemia

Identifiers

Type Value
UniprotQ60953
UniprotA0A068EW80
MGI104662

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001666
IMP
ISS, ISO
IEA
Genome Projectresponse to hypoxia
GO:0002230
ISO
IEA
Genome Projectpositive regulation of defense response to virus by host
GO:0006355
IDA
ISO
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006461
ISS, ISO
IEA
Genome Projectprotein complex assembly
GO:0006605
ISS, ISO
IEA
Genome Projectprotein targeting
GO:0006915
ISO
IEA
Genome Projectapoptotic process
GO:0006919
IMP
Genome Projectactivation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007050
IMP
ISO
IEA
Genome Projectcell cycle arrest
GO:0007179
IMP
Genome Projecttransforming growth factor beta receptor signaling pathway
GO:0007182
IMP
Genome Projectcommon-partner SMAD protein phosphorylation
GO:0007184
IMP
Genome ProjectSMAD protein import into nucleus
GO:0008285
IMP
ISO
IEA
Genome Projectnegative regulation of cell proliferation
GO:0008630
IMP
ISO
IEA
Genome Projectintrinsic apoptotic signaling pathway in response to DNA damage
GO:0008631
IMP
Genome Projectintrinsic apoptotic signaling pathway in response to oxidative stress
GO:0009411
IMP
Genome Projectresponse to UV
GO:0010332
IMP
Genome Projectresponse to gamma radiation
GO:0016525
IMP
ISS, ISO
IEA
Genome Projectnegative regulation of angiogenesis
GO:0030099
IMP
Genome Projectmyeloid cell differentiation
GO:0030308
ISS, ISO
IEA
Genome Projectnegative regulation of cell growth
GO:0030578
IDA
ISO
IEA
Genome ProjectPML body organization
GO:0031065
ISS, ISO
IEA
Genome Projectpositive regulation of histone deacetylation
GO:0032211
ISO
IEA
Genome Projectnegative regulation of telomere maintenance via telomerase
GO:0032938
ISO
IEA
Genome Projectnegative regulation of translation in response to oxidative stress
GO:0034097
ISO
IEA
Genome Projectresponse to cytokine
GO:0043161
ISS, ISO
IEA
Genome Projectproteasome-mediated ubiquitin-dependent protein catabolic process
GO:0045087
IDA
ISO
IEA
Genome Projectinnate immune response
GO:0045165
IMP
Genome Projectcell fate commitment
GO:0045892
ISS, ISO
IEA
Genome Projectnegative regulation of transcription, DNA-templated
GO:0045930
ISO
IEA
Genome Projectnegative regulation of mitotic cell cycle
GO:0048384
IMP
Genome Projectretinoic acid receptor signaling pathway
GO:0050821
ISO
IEA
Genome Projectprotein stabilization
GO:0051457
ISO
IEA
Genome Projectmaintenance of protein location in nucleus
GO:0051974
ISO
IEA
Genome Projectnegative regulation of telomerase activity
GO:0060058
ISO
IEA
Genome Projectpositive regulation of apoptotic process involved in mammary gland involution
GO:0060444
IMP
Genome Projectbranching involved in mammary gland duct morphogenesis
GO:0070059
IMP
Genome Projectintrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0071353
IDA
Genome Projectcellular response to interleukin-4
GO:0072332
IMP
Genome Projectintrinsic apoptotic signaling pathway by p53 class mediator
GO:0090398
ISS, ISO
IEA
Genome Projectcellular senescence
GO:0097191
IMP
Genome Projectextrinsic apoptotic signaling pathway
GO:1902187
IDA
ISO
IEA
Genome Projectnegative regulation of viral release from host cell
GO:2000059
ISO
IEA
Genome Projectnegative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:2000779
ISS, ISO
IEA
Genome Projectregulation of double-strand break repair
GO:2001235
IMP, IGI
Genome Projectpositive regulation of apoptotic signaling pathway
GO:2001238
ISO
IEA
Genome Projectpositive regulation of extrinsic apoptotic signaling pathway
GO:0001932
IMP
Genome Projectregulation of protein phosphorylation
GO:0002376
IEA
Genome Projectimmune system process
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006977
IMP
Genome ProjectDNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0007569
IMP
Genome Projectcell aging
GO:0010522
IMP
Genome Projectregulation of calcium ion transport into cytosol
GO:0010761
IMP
Genome Projectfibroblast migration
GO:0016032
IEA
Genome Projectviral process
GO:0030155
IMP
Genome Projectregulation of cell adhesion
GO:0032469
IMP
Genome Projectendoplasmic reticulum calcium ion homeostasis
GO:0032922
IDA
Genome Projectcircadian regulation of gene expression
GO:0042752
IDA
Genome Projectregulation of circadian rhythm
GO:0042771
IMP
Genome Projectintrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0043153
IDA
Genome Projectentrainment of circadian clock by photoperiod
GO:0045343
IDA
Genome Projectregulation of MHC class I biosynthetic process
GO:0048146
IMP
Genome Projectpositive regulation of fibroblast proliferation
GO:0048511
IEA
Genome Projectrhythmic process
GO:0050711
IMP
Genome Projectnegative regulation of interleukin-1 secretion
GO:0050713
IMP
Genome Projectnegative regulation of interleukin-1 beta secretion
GO:0051607
IEA
Genome Projectdefense response to virus

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003713
ISO
TAS, IEA
Genome Projecttranscription coactivator activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008270
ISO
IEA
Genome Projectzinc ion binding
GO:0031625
ISO
IEA
Genome Projectubiquitin protein ligase binding
GO:0032183
ISO
IEA
Genome ProjectSUMO binding
GO:0042803
ISO
IEA
Genome Projectprotein homodimerization activity
GO:0046332
IDA
Genome ProjectSMAD binding
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0046982
ISO
IEA
Genome Projectprotein heterodimerization activity
GO:0050897
ISO
IEA
Genome Projectcobalt ion binding
GO:0003677
IEA
Genome ProjectDNA binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005622
IEA
Genome Projectintracellular
GO:0005634
IDA
ISO
IEA
Genome Projectnucleus
GO:0005654
ISS, ISO
IEA
Genome Projectnucleoplasm
GO:0005730
ISS, ISO
IEA
Genome Projectnucleolus
GO:0005737
ISO
IEA
Genome Projectcytoplasm
GO:0016363
IDA
ISO
IEA
Genome Projectnuclear matrix
GO:0016605
IDA, IMP
ISS, ISO
IEA
Genome ProjectPML body
GO:0031965
ISO
IEA
Genome Projectnuclear membrane
GO:0005768
IEA
Genome Projectendosome
GO:0005783
IEA
Genome Projectendoplasmic reticulum
GO:0005789
IEA
Genome Projectendoplasmic reticulum membrane
GO:0005829
IDA
Genome Projectcytosol
GO:0016020
IEA
Genome Projectmembrane
GO:0031901
IEA
Genome Projectearly endosome membrane
GO:0042406
IDA
Genome Projectextrinsic component of endoplasmic reticulum membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000315B-box-type zinc finger
IPR001841Zinc finger, RING-type
IPR013083Zinc finger, RING/FYVE/PHD-type
IPR017907Zinc finger, RING-type, conserved site
IPR021978Protein of unknown function DUF3583

No MapMan annotations defined for this gene.