Gene: ENSMUSG00000036940 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000036940
Transcript Identifier
ENSMUST00000105847
Gene Type
Coding gene
Location
4 : 136550848-136602585 : negative

Family Information

Homologous gene family
HOM03P000222
(160 genes in 36 species)
specific family
Orthologous gene family
ORTHO03P003422
(24 genes in 22 species)
specific family

Descriptions

gene_descr
lysine (K)-specific demethylase 1A

Identifiers

Type Value
UniprotA3KG93
MGI1196256

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
IMP
ISO
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0001701
IMP
Genome Projectin utero embryonic development
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006357
ISO
Genome Projectregulation of transcription from RNA polymerase II promoter
GO:0006482
ISO
Genome Projectprotein demethylation
GO:0008283
IMP
Genome Projectcell proliferation
GO:0021983
IMP
Genome Projectpituitary gland development
GO:0032091
ISO
Genome Projectnegative regulation of protein binding
GO:0033169
ISO
Genome Projecthistone H3-K9 demethylation
GO:0034720
IDA
ISO
IEA
Genome Projecthistone H3-K4 demethylation
GO:0043433
ISO
Genome Projectnegative regulation of sequence-specific DNA binding transcription factor activity
GO:0043518
ISO
Genome Projectnegative regulation of DNA damage response, signal transduction by p53 class mediator
GO:0045892
ISO
Genome Projectnegative regulation of transcription, DNA-templated
GO:0045944
IMP
ISO
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0046886
IMP
Genome Projectpositive regulation of hormone biosynthetic process
GO:0051091
ISO
Genome Projectpositive regulation of sequence-specific DNA binding transcription factor activity
GO:0055114
IEA
Genome Projectoxidation-reduction process
GO:1902166
ISO
Genome Projectnegative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002039
ISO
Genome Projectp53 binding
GO:0003677
IEA
Genome ProjectDNA binding
GO:0003682
ISO
Genome Projectchromatin binding
GO:0003700
IDA
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0008134
IPI
ISO
Genome Projecttranscription factor binding
GO:0016491
ISO
IEA
Genome Projectoxidoreductase activity
GO:0019899
ISO
Genome Projectenzyme binding
GO:0030374
ISO
Genome Projectligand-dependent nuclear receptor transcription coactivator activity
GO:0032451
ISO
Genome Projectdemethylase activity
GO:0032452
ISO
Genome Projecthistone demethylase activity
GO:0032453
ISO
Genome Projecthistone demethylase activity (H3-K4 specific)
GO:0032454
ISO
Genome Projecthistone demethylase activity (H3-K9 specific)
GO:0034648
IDA
ISO
Genome Projecthistone demethylase activity (H3-dimethyl-K4 specific)
GO:0043426
ISO
Genome ProjectMRF binding
GO:0050660
ISO
IEA
Genome Projectflavin adenine dinucleotide binding
GO:0050681
ISO
Genome Projectandrogen receptor binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000790
ISO
Genome Projectnuclear chromatin
GO:0005634
ISO
IEA
Genome Projectnucleus
GO:0005654
ISO
Genome Projectnucleoplasm
GO:0005667
IDA
Genome Projecttranscription factor complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR002937Amine oxidase
IPR007526SWIRM domain
IPR009057Homeodomain-like
IPR011991Winged helix-turn-helix DNA-binding domain
IPR017366Histone lysine-specific demethylase
IPR023753FAD/NAD(P)-binding domain

No MapMan annotations defined for this gene.