Gene: ENSMUSG00000035960 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000035960
Transcript Identifier
ENSMUST00000049411
Gene Type
Coding gene
Location
14 : 50925270-50926973 : positive

Family Information

Homologous gene family
HOM03P000925
(65 genes in 35 species)
specific family
Orthologous gene family
ORTHO03P000453
(50 genes in 35 species)
specific family

Descriptions

gene_descr
apurinic/apyrimidinic endonuclease 1

Identifiers

Type Value
UniprotP28352
UniprotQ544Z7
MGI88042

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006281
ISS, ISO
IEA
Genome ProjectDNA repair
GO:0006284
IBA
Genome Projectbase-excision repair
GO:0006310
IEA
Genome ProjectDNA recombination
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006974
IEA
Genome Projectcellular response to DNA damage stimulus
GO:0043488
ISS, ISO
IEA
Genome Projectregulation of mRNA stability
GO:0045454
IDA
Genome Projectcell redox homeostasis
GO:0045739
ISS, ISO
IEA
Genome Projectpositive regulation of DNA repair
GO:0055114
ISO
IEA
Genome Projectoxidation-reduction process
GO:0080111
ISS, ISO
IEA
Genome ProjectDNA demethylation
GO:0090305
ISO
Genome Projectnucleic acid phosphodiester bond hydrolysis
GO:1903506
ISO
IEA
Genome Projectregulation of nucleic acid-templated transcription

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003677
ISS, ISO
IEA
Genome ProjectDNA binding
GO:0003684
ISS, ISO
IEA
Genome Projectdamaged DNA binding
GO:0003713
ISS, ISO
IEA
Genome Projecttranscription coactivator activity
GO:0003723
IEA
Genome ProjectRNA binding
GO:0003906
ISS, ISO, IBA
IEA
Genome ProjectDNA-(apurinic or apyrimidinic site) lyase activity
GO:0004518
IEA
Genome Projectnuclease activity
GO:0004519
IEA
Genome Projectendonuclease activity
GO:0004527
IEA
Genome Projectexonuclease activity
GO:0008081
IEA
Genome Projectphosphoric diester hydrolase activity
GO:0008311
IBA
Genome Projectdouble-stranded DNA 3'-5' exodeoxyribonuclease activity
GO:0008408
ISS, ISO
Genome Project3'-5' exonuclease activity
GO:0016491
ISS, ISO
IEA
Genome Projectoxidoreductase activity
GO:0016787
IEA
Genome Projecthydrolase activity
GO:0016829
IEA
Genome Projectlyase activity
GO:0016890
ISS, ISO
IEA
Genome Projectsite-specific endodeoxyribonuclease activity, specific for altered base
GO:0031490
ISS, ISO
IEA
Genome Projectchromatin DNA binding
GO:0044822
ISO
IEA
Genome Projectpoly(A) RNA binding
GO:0046872
ISS, ISO
IEA
Genome Projectmetal ion binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005622
IEA
Genome Projectintracellular
GO:0005634
IDA
ISS, ISO
IEA
Genome Projectnucleus
GO:0005654
ISS, ISO
IEA
Genome Projectnucleoplasm
GO:0005730
ISS, ISO
IEA
Genome Projectnucleolus
GO:0005737
IDA
ISO
IEA
Genome Projectcytoplasm
GO:0005739
ISS, ISO
IEA
Genome Projectmitochondrion
GO:0005783
IEA
Genome Projectendoplasmic reticulum
GO:0005813
ISO
IEA
Genome Projectcentrosome
GO:0016607
ISS, ISO
IEA
Genome Projectnuclear speck
GO:0048471
ISS, ISO
IEA
Genome Projectperinuclear region of cytoplasm

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR004808AP endonuclease 1
IPR005135Endonuclease/exonuclease/phosphatase
IPR020847AP endonuclease 1, binding site
IPR020848AP endonuclease 1, conserved site

No MapMan annotations defined for this gene.