Gene: ENSMUSG00000034330 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000034330
Transcript Identifier
ENSMUST00000081232
Gene Type
Coding gene
Location
8 : 117504181-117634827 : positive

Family Information

Homologous gene family
HOM03P000424
(107 genes in 28 species)
specific family
Orthologous gene family
ORTHO03P014366
(6 genes in 4 species)
specific family

Descriptions

gene_descr
phospholipase C, gamma 2

Identifiers

Type Value
UniprotQ8CIH5
MGI97616

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002092
IMP
Genome Projectpositive regulation of receptor internalization
GO:0002316
IMP
Genome Projectfollicular B cell differentiation
GO:0006629
IEA
Genome Projectlipid metabolic process
GO:0006661
ISS, ISO
IEA
Genome Projectphosphatidylinositol biosynthetic process
GO:0007165
IEA
Genome Projectsignal transduction
GO:0009395
IEA
Genome Projectphospholipid catabolic process
GO:0010468
IMP
Genome Projectregulation of gene expression
GO:0016042
IEA
Genome Projectlipid catabolic process
GO:0030183
IMP
Genome ProjectB cell differentiation
GO:0032237
IMP
Genome Projectactivation of store-operated calcium channel activity
GO:0032481
IMP
Genome Projectpositive regulation of type I interferon production
GO:0032496
IDA
Genome Projectresponse to lipopolysaccharide
GO:0032959
IDA
Genome Projectinositol trisphosphate biosynthetic process
GO:0035556
IEA
Genome Projectintracellular signal transduction
GO:0043069
IMP
Genome Projectnegative regulation of programmed cell death
GO:0050852
IDA
Genome ProjectT cell receptor signaling pathway
GO:0050853
IMP
Genome ProjectB cell receptor signaling pathway
GO:0051209
IMP
ISO
IEA
Genome Projectrelease of sequestered calcium ion into cytosol

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004435
ISS, ISO
IEA
Genome Projectphosphatidylinositol phospholipase C activity
GO:0004629
TAS
Genome Projectphospholipase C activity
GO:0004871
IEA
Genome Projectsignal transducer activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008081
IEA
Genome Projectphosphoric diester hydrolase activity
GO:0016787
IEA
Genome Projecthydrolase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005829
IMP
TAS
Genome Projectcytosol
GO:0005886
ISS, ISO
IEA
Genome Projectplasma membrane
GO:0070062
ISO
IEA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000008C2 domain
IPR000909Phosphatidylinositol-specific phospholipase C, X domain
IPR000980SH2 domain
IPR001192Phosphoinositide phospholipase C family
IPR001452SH3 domain
IPR001711Phospholipase C, phosphatidylinositol-specific, Y domain
IPR001849Pleckstrin homology domain
IPR011993PH domain-like
IPR016279Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma
IPR017946PLC-like phosphodiesterase, TIM beta/alpha-barrel domain
IPR0283811-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2

No MapMan annotations defined for this gene.