Gene: ENSMUSG00000033335 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000033335
Transcript Identifier
ENSMUST00000172482
Gene Type
Coding gene
Location
9 : 21425096-21506402 : positive

Family Information

Homologous gene family
HOM03P000185
(176 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P000310
(55 genes in 38 species)
specific family

Descriptions

gene_descr
dynamin 2

Identifiers

Type Value
UniprotP39054
MGI109547

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002031
IEA
Genome ProjectG-protein coupled receptor internalization
GO:0006893
IEA
Genome ProjectGolgi to plasma membrane transport
GO:0006897
IEA
Genome Projectendocytosis
GO:0006898
ISS
IEA
Genome Projectreceptor-mediated endocytosis
GO:0007283
IEA
Genome Projectspermatogenesis
GO:0009416
IEA
Genome Projectresponse to light stimulus
GO:0010592
IEA
Genome Projectpositive regulation of lamellipodium assembly
GO:0030512
IEA
Genome Projectnegative regulation of transforming growth factor beta receptor signaling pathway
GO:0030516
ISS
IEA
Genome Projectregulation of axon extension
GO:0031623
ISO
IEA
Genome Projectreceptor internalization
GO:0033572
ISO
IEA
Genome Projecttransferrin transport
GO:0035020
IEA
Genome Projectregulation of Rac protein signal transduction
GO:0042220
IEA
Genome Projectresponse to cocaine
GO:0044351
IEA
Genome Projectmacropinocytosis
GO:0045429
IEA
Genome Projectpositive regulation of nitric oxide biosynthetic process
GO:0045807
IEA
Genome Projectpositive regulation of endocytosis
GO:0048812
ISS
IEA
Genome Projectneuron projection morphogenesis
GO:0050766
IEA
Genome Projectpositive regulation of phagocytosis
GO:0060271
IEA
Genome Projectcilium morphogenesis
GO:0071245
IEA
Genome Projectcellular response to carbon monoxide
GO:0071481
IEA
Genome Projectcellular response to X-ray
GO:0071732
IEA
Genome Projectcellular response to nitric oxide
GO:1900026
IEA
Genome Projectpositive regulation of substrate adhesion-dependent cell spreading
GO:1903351
IEA
Genome Projectcellular response to dopamine
GO:1903358
IEA
Genome Projectregulation of Golgi organization
GO:1903408
IEA
Genome Projectpositive regulation of sodium:potassium-exchanging ATPase activity
GO:1903526
ISO
IEA
Genome Projectnegative regulation of membrane tubulation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0003924
IEA
Genome ProjectGTPase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005525
IEA
Genome ProjectGTP binding
GO:0016787
IEA
Genome Projecthydrolase activity
GO:0017124
ISO
IEA
Genome ProjectSH3 domain binding
GO:0019901
IEA
Genome Projectprotein kinase binding
GO:0031749
IEA
Genome ProjectD2 dopamine receptor binding
GO:0032403
IEA
Genome Projectprotein complex binding
GO:0036312
IEA
Genome Projectphosphatidylinositol 3-kinase regulatory subunit binding
GO:0050699
IEA
Genome ProjectWW domain binding
GO:0050998
IEA
Genome Projectnitric-oxide synthase binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000139
IEA
Genome ProjectGolgi membrane
GO:0001891
IEA
Genome Projectphagocytic cup
GO:0001917
IDA
Genome Projectphotoreceptor inner segment
GO:0005634
IEA
Genome Projectnucleus
GO:0005737
ISO
IEA
Genome Projectcytoplasm
GO:0005768
IEA
Genome Projectendosome
GO:0005794
ISO
IEA
Genome ProjectGolgi apparatus
GO:0005802
IEA
Genome Projecttrans-Golgi network
GO:0005813
IEA
Genome Projectcentrosome
GO:0005829
ISO
IEA
Genome Projectcytosol
GO:0005856
IEA
Genome Projectcytoskeleton
GO:0005874
ISO
IEA
Genome Projectmicrotubule
GO:0005886
IEA
Genome Projectplasma membrane
GO:0005905
ISS
IEA
Genome Projectcoated pit
GO:0005925
ISO
IEA
Genome Projectfocal adhesion
GO:0014069
IEA
Genome Projectpostsynaptic density
GO:0016020
IEA
Genome Projectmembrane
GO:0030027
IEA
Genome Projectlamellipodium
GO:0030054
ISS
IEA
Genome Projectcell junction
GO:0030426
ISS
IEA
Genome Projectgrowth cone
GO:0030496
IEA
Genome Projectmidbody
GO:0032587
IEA
Genome Projectruffle membrane
GO:0043234
IEA
Genome Projectprotein complex
GO:0045202
IEA
Genome Projectsynapse
GO:0045211
ISO
IEA
Genome Projectpostsynaptic membrane
GO:0045334
IEA
Genome Projectclathrin-coated endocytic vesicle
GO:0048471
IEA
Genome Projectperinuclear region of cytoplasm
GO:0070062
ISO
IEA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000375Dynamin central domain
IPR001401Dynamin, GTPase domain
IPR001849Pleckstrin homology domain
IPR003130Dynamin GTPase effector
IPR011993PH domain-like
IPR019762Dynamin, GTPase region, conserved site
IPR020850GTPase effector domain
IPR022812Dynamin superfamily
IPR027188Dynamin-2
IPR027417P-loop containing nucleoside triphosphate hydrolase
IPR030381Dynamin-type guanine nucleotide-binding (G) domain

No MapMan annotations defined for this gene.