Gene: ENSMUSG00000033307 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000033307
Transcript Identifier
ENSMUST00000038169
Gene Type
Coding gene
Location
10 : 75859477-75860168 : negative

Family Information

Homologous gene family
HOM03P002612
(35 genes in 25 species)
specific family

Descriptions

gene_descr
macrophage migration inhibitory factor

Identifiers

Type Value
UniprotP34884
UniprotQ545F0
MGI96982

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001516
ISO
IEA
Genome Projectprostaglandin biosynthetic process
GO:0001934
IDA
Genome Projectpositive regulation of protein phosphorylation
GO:0002376
IEA
Genome Projectimmune system process
GO:0002821
NAS
Genome Projectpositive regulation of adaptive immune response
GO:0002906
IDA
Genome Projectnegative regulation of mature B cell apoptotic process
GO:0006954
IEA
Genome Projectinflammatory response
GO:0007166
ISO
IEA
Genome Projectcell surface receptor signaling pathway
GO:0007569
IMP
Genome Projectcell aging
GO:0008283
ISO
IEA
Genome Projectcell proliferation
GO:0010629
ISO
IEA
Genome Projectnegative regulation of gene expression
GO:0010739
ISO
IEA
Genome Projectpositive regulation of protein kinase A signaling
GO:0019752
ISO
IEA
Genome Projectcarboxylic acid metabolic process
GO:0030330
IMP
Genome ProjectDNA damage response, signal transduction by p53 class mediator
GO:0030890
ISO
IEA
Genome Projectpositive regulation of B cell proliferation
GO:0031666
IMP
Genome Projectpositive regulation of lipopolysaccharide-mediated signaling pathway
GO:0032269
IDA
Genome Projectnegative regulation of cellular protein metabolic process
GO:0033033
IMP
Genome Projectnegative regulation of myeloid cell apoptotic process
GO:0033138
IDA
ISO
IEA
Genome Projectpositive regulation of peptidyl-serine phosphorylation
GO:0042127
IMP
Genome Projectregulation of cell proliferation
GO:0042327
ISO
IEA
Genome Projectpositive regulation of phosphorylation
GO:0043066
IDA
ISO
IEA
Genome Projectnegative regulation of apoptotic process
GO:0043406
IDA
Genome Projectpositive regulation of MAP kinase activity
GO:0043518
IDA
ISO
IEA
Genome Projectnegative regulation of DNA damage response, signal transduction by p53 class mediator
GO:0045087
IEA
Genome Projectinnate immune response
GO:0048146
IDA
ISO
IEA
Genome Projectpositive regulation of fibroblast proliferation
GO:0050715
ISO
IEA
Genome Projectpositive regulation of cytokine secretion
GO:0050731
IDA
ISO
IEA
Genome Projectpositive regulation of peptidyl-tyrosine phosphorylation
GO:0050918
ISO
IEA
Genome Projectpositive chemotaxis
GO:0061078
IMP
Genome Projectpositive regulation of prostaglandin secretion involved in immune response
GO:0061081
IMP
Genome Projectpositive regulation of myeloid leukocyte cytokine production involved in immune response
GO:0070207
ISO
IEA
Genome Projectprotein homotrimerization
GO:0070374
IDA
ISO
IEA
Genome Projectpositive regulation of ERK1 and ERK2 cascade
GO:0071157
ISO
IEA
Genome Projectnegative regulation of cell cycle arrest
GO:0090238
IDA
Genome Projectpositive regulation of arachidonic acid secretion
GO:0090344
ISO
IEA
Genome Projectnegative regulation of cell aging
GO:1902166
ISO
IEA
Genome Projectnegative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:2000343
IDA
Genome Projectpositive regulation of chemokine (C-X-C motif) ligand 2 production

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004167
ISS, ISO
IEA
Genome Projectdopachrome isomerase activity
GO:0005102
ISO
IEA
Genome Projectreceptor binding
GO:0005125
IDA
ISO
IEA
Genome Projectcytokine activity
GO:0005126
ISO
IEA
Genome Projectcytokine receptor binding
GO:0016853
IEA
Genome Projectisomerase activity
GO:0042056
ISO
IEA
Genome Projectchemoattractant activity
GO:0050178
IMP
ISO
IEA
Genome Projectphenylpyruvate tautomerase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
ISO
IEA
Genome Projectextracellular region
GO:0005615
IDA
IEA
Genome Projectextracellular space
GO:0005654
ISO
IEA
Genome Projectnucleoplasm
GO:0005737
ISO
IEA
Genome Projectcytoplasm
GO:0009986
ISO
IEA
Genome Projectcell surface
GO:0031982
ISO
IEA
Genome Projectvesicle
GO:0043209
IDA
Genome Projectmyelin sheath
GO:0070062
ISO
IEA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001398Macrophage migration inhibitory factor
IPR014347Tautomerase/MIF superfamily
IPR019829Macrophage migration inhibitory factor, conserved site

No MapMan annotations defined for this gene.