Gene: ENSMUSG00000032855 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000032855
Transcript Identifier
ENSMUST00000035565
Gene Type
Coding gene
Location
17 : 24550263-24595539 : positive

Family Information

Homologous gene family
HOM03P007044
(12 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P073360
(2 genes in 2 species)
specific family

Descriptions

gene_descr
polycystic kidney disease 1 homolog

Identifiers

Type Value
UniprotO08852
MGI97603

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001502
IMP
Genome Projectcartilage condensation
GO:0001568
IMP
Genome Projectblood vessel development
GO:0001701
IMP, IGI
Genome Projectin utero embryonic development
GO:0001822
IMP, IGI
IEA
Genome Projectkidney development
GO:0001889
IGI
Genome Projectliver development
GO:0001892
IMP
Genome Projectembryonic placenta development
GO:0006611
IMP
Genome Projectprotein export from nucleus
GO:0006807
IGI
Genome Projectnitrogen compound metabolic process
GO:0006816
IMP
Genome Projectcalcium ion transport
GO:0007050
IDA
Genome Projectcell cycle arrest
GO:0007204
IEA
Genome Projectpositive regulation of cytosolic calcium ion concentration
GO:0007259
IDA
Genome ProjectJAK-STAT cascade
GO:0007507
IMP
IEA
Genome Projectheart development
GO:0016337
IMP
Genome Projectsingle organismal cell-cell adhesion
GO:0018105
IMP
Genome Projectpeptidyl-serine phosphorylation
GO:0021510
IEA
Genome Projectspinal cord development
GO:0021915
IEA
Genome Projectneural tube development
GO:0030010
IMP
Genome Projectestablishment of cell polarity
GO:0030155
IMP
Genome Projectregulation of cell adhesion
GO:0031659
ISO
IEA
Genome Projectpositive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle
GO:0032092
IMP
Genome Projectpositive regulation of protein binding
GO:0034405
IMP
Genome Projectresponse to fluid shear stress
GO:0036303
IMP
Genome Projectlymph vessel morphogenesis
GO:0042994
IMP
Genome Projectcytoplasmic sequestering of transcription factor
GO:0043588
IEA
Genome Projectskin development
GO:0045944
ISO
IEA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0048565
IEA
Genome Projectdigestive tract development
GO:0048754
IDA
ISO
IEA
Genome Projectbranching morphogenesis of an epithelial tube
GO:0048806
IEA
Genome Projectgenitalia development
GO:0050982
IDA, IMP
Genome Projectdetection of mechanical stimulus
GO:0051216
IEA
Genome Projectcartilage development
GO:0060236
IMP
Genome Projectregulation of mitotic spindle organization
GO:0060428
IEA
Genome Projectlung epithelium development
GO:0060674
IMP
Genome Projectplacenta blood vessel development
GO:0061136
IMP
ISO
IEA
Genome Projectregulation of proteasomal protein catabolic process
GO:0070588
IMP
Genome Projectcalcium ion transmembrane transport
GO:0072001
IGI
Genome Projectrenal system development
GO:0072164
IEA
Genome Projectmesonephric tubule development
GO:0072177
IEA
Genome Projectmesonephric duct development
GO:0072205
IEA
Genome Projectmetanephric collecting duct development
GO:0072218
IEA
Genome Projectmetanephric ascending thin limb development
GO:0072237
IEA
Genome Projectmetanephric proximal tubule development
GO:0072287
IEA
Genome Projectmetanephric distal tubule morphogenesis

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005262
IMP
TAS
Genome Projectcalcium channel activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0019901
ISO
IEA
Genome Projectprotein kinase binding
GO:0019904
ISO
IEA
Genome Projectprotein domain specific binding
GO:0030246
IEA
Genome Projectcarbohydrate binding
GO:0044325
ISO
IEA
Genome Projection channel binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002133
IDA
Genome Projectpolycystin complex
GO:0005634
IDA
Genome Projectnucleus
GO:0005737
IMP
Genome Projectcytoplasm
GO:0005794
IEA
Genome ProjectGolgi apparatus
GO:0005829
IEA
Genome Projectcytosol
GO:0005886
ISO
IEA
Genome Projectplasma membrane
GO:0005929
IDA
IEA
Genome Projectcilium
GO:0009986
IDA
Genome Projectcell surface
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0016323
ISO
IEA
Genome Projectbasolateral plasma membrane
GO:0016328
IEA
Genome Projectlateral plasma membrane
GO:0031512
IDA
Genome Projectmotile primary cilium
GO:0042995
IEA
Genome Projectcell projection
GO:0070062
ISO
IEA
Genome Projectextracellular exosome
GO:0072372
IDA
Genome Projectprimary cilium

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000203GPS motif
IPR000372Leucine-rich repeat N-terminal domain
IPR000434Polycystic kidney disease type 1 protein
IPR000483Cysteine-rich flanking region, C-terminal
IPR000601PKD domain
IPR001024PLAT/LH2 domain
IPR001304C-type lectin
IPR001611Leucine-rich repeat
IPR002859PKD/REJ-like domain
IPR002889Carbohydrate-binding WSC
IPR003591Leucine-rich repeat, typical subtype
IPR006228Polycystin cation channel
IPR013122Polycystin cation channel, PKD1/PKD2
IPR013994Carbohydrate-binding WSC, subgroup
IPR014010REJ domain
IPR016186C-type lectin-like
IPR016187C-type lectin fold
IPR022409PKD/Chitinase domain

No MapMan annotations defined for this gene.