Gene: ENSMUSG00000032715 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000032715
Transcript Identifier
ENSMUST00000040312
Gene Type
Coding gene
Location
2 : 152338207-152343327 : negative

Family Information

Homologous gene family
HOM03P000001
(4368 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P076262
(2 genes in 2 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
tribbles homolog 3 (Drosophila)

Identifiers

Type Value
UniprotQ8K4K2
MGI1345675

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
ISO
IEA
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006468
IEA
Genome Projectprotein phosphorylation
GO:0006469
IDA
ISO
IEA
Genome Projectnegative regulation of protein kinase activity
GO:0006915
IEA
Genome Projectapoptotic process
GO:0010827
IDA
Genome Projectregulation of glucose transport
GO:0032092
IDA
Genome Projectpositive regulation of protein binding
GO:0032436
TAS
Genome Projectpositive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032869
IDA
Genome Projectcellular response to insulin stimulus
GO:0034976
ISS, ISO
IEA
Genome Projectresponse to endoplasmic reticulum stress
GO:0043405
ISS, ISO, IBA
IEA
Genome Projectregulation of MAP kinase activity
GO:0045599
IMP
Genome Projectnegative regulation of fat cell differentiation
GO:0045717
IMP
Genome Projectnegative regulation of fatty acid biosynthetic process
GO:0045732
IC
Genome Projectpositive regulation of protein catabolic process
GO:0045892
ISS, ISO
IEA
Genome Projectnegative regulation of transcription, DNA-templated
GO:0051443
IDA
Genome Projectpositive regulation of ubiquitin-protein transferase activity
GO:0070059
ISS, ISO
IEA
Genome Projectintrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:1904030
IEA
Genome Projectnegative regulation of cyclin-dependent protein kinase activity

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003714
IDA
IEA
Genome Projecttranscription corepressor activity
GO:0004860
IEA
Genome Projectprotein kinase inhibitor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005524
IEA
Genome ProjectATP binding
GO:0019899
IPI
Genome Projectenzyme binding
GO:0019901
IPI
ISS, ISO
Genome Projectprotein kinase binding
GO:0031434
IBA
Genome Projectmitogen-activated protein kinase kinase binding
GO:0031625
IDA, IPI
Genome Projectubiquitin protein ligase binding
GO:0055106
IDA
Genome Projectubiquitin-protein transferase regulator activity
GO:0016301
ISS
Genome Projectkinase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005654
ISO
IEA
Genome Projectnucleoplasm

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000719Protein kinase domain
IPR011009Protein kinase-like domain
IPR024104Pseudokinase tribbles family/serine-threonine-protein kinase 40
IPR024106Pseudokinase tribbles, TRB3

No MapMan annotations defined for this gene.