Gene: ENSMUSG00000032537 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000032537
Transcript Identifier
ENSMUST00000035129
Gene Type
Coding gene
Location
9 : 101923486-102354339 : negative

Family Information

Homologous gene family
HOM03P000004
(1817 genes in 37 species)
specific family
Orthologous gene family
ORTHO03P003318
(24 genes in 4 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
Eph receptor B1

Identifiers

Type Value
UniprotQ8CBF3
MGI1096337

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001525
ISS, ISO
IEA
Genome Projectangiogenesis
GO:0001771
ISO
IEA
Genome Projectimmunological synapse formation
GO:0006468
IEA
Genome Projectprotein phosphorylation
GO:0007155
IEA
Genome Projectcell adhesion
GO:0007169
IEA
Genome Projecttransmembrane receptor protein tyrosine kinase signaling pathway
GO:0007399
IEA
Genome Projectnervous system development
GO:0007411
IDA, IMP
Genome Projectaxon guidance
GO:0016310
IEA
Genome Projectphosphorylation
GO:0018108
IEA
Genome Projectpeptidyl-tyrosine phosphorylation
GO:0021545
IMP
Genome Projectcranial nerve development
GO:0021631
IMP
Genome Projectoptic nerve morphogenesis
GO:0021952
IDA, IMP
Genome Projectcentral nervous system projection neuron axonogenesis
GO:0022008
IMP
Genome Projectneurogenesis
GO:0030010
IMP
Genome Projectestablishment of cell polarity
GO:0031290
IDA
Genome Projectretinal ganglion cell axon guidance
GO:0031589
ISS, ISO
IEA
Genome Projectcell-substrate adhesion
GO:0046328
ISS, ISO
IEA
Genome Projectregulation of JNK cascade
GO:0046777
ISS, ISO
IEA
Genome Projectprotein autophosphorylation
GO:0048013
IDA
ISS, ISO
IEA
Genome Projectephrin receptor signaling pathway
GO:0048593
IMP
Genome Projectcamera-type eye morphogenesis
GO:0050965
IMP
Genome Projectdetection of temperature stimulus involved in sensory perception of pain
GO:0051965
IMP
Genome Projectpositive regulation of synapse assembly
GO:0060326
IMP
ISO
IEA
Genome Projectcell chemotaxis
GO:0060996
IMP
ISO
Genome Projectdendritic spine development
GO:0060997
IMP
Genome Projectdendritic spine morphogenesis
GO:0061351
IMP
Genome Projectneural precursor cell proliferation
GO:0070372
ISS, ISO
IEA
Genome Projectregulation of ERK1 and ERK2 cascade
GO:1901214
ISO
IEA
Genome Projectregulation of neuron death

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0004672
IEA
Genome Projectprotein kinase activity
GO:0004713
IEA
Genome Projectprotein tyrosine kinase activity
GO:0004714
IEA
Genome Projecttransmembrane receptor protein tyrosine kinase activity
GO:0005003
IEA
Genome Projectephrin receptor activity
GO:0005005
ISS, ISO
TAS, IEA
Genome Projecttransmembrane-ephrin receptor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005524
IEA
Genome ProjectATP binding
GO:0008046
IDA
Genome Projectaxon guidance receptor activity
GO:0016301
IEA
Genome Projectkinase activity
GO:0016740
IEA
Genome Projecttransferase activity
GO:0032403
IPI
Genome Projectprotein complex binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IDA
Genome Projectcytoplasm
GO:0005768
IEA
Genome Projectendosome
GO:0005886
IEA
Genome Projectplasma membrane
GO:0005887
ISS, ISO
TAS, IEA
Genome Projectintegral component of plasma membrane
GO:0016020
IDA
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0030424
IDA
Genome Projectaxon
GO:0030425
IEA
Genome Projectdendrite
GO:0031901
ISS, ISO
IEA
Genome Projectearly endosome membrane
GO:0032433
IDA
Genome Projectfilopodium tip
GO:0042995
IEA
Genome Projectcell projection
GO:0045121
IDA
Genome Projectmembrane raft
GO:0070062
ISO
IEA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000719Protein kinase domain
IPR001090Ephrin receptor ligand binding domain
IPR001245Serine-threonine/tyrosine-protein kinase catalytic domain
IPR001426Tyrosine-protein kinase, receptor class V, conserved site
IPR001660Sterile alpha motif domain
IPR003961Fibronectin type III
IPR008266Tyrosine-protein kinase, active site
IPR008979Galactose-binding domain-like
IPR009030Growth factor receptor cysteine-rich domain
IPR011009Protein kinase-like domain
IPR013761Sterile alpha motif/pointed domain
IPR013783Immunoglobulin-like fold
IPR016257Ephrin receptor type-A /type-B
IPR017441Protein kinase, ATP binding site
IPR020635Tyrosine-protein kinase, catalytic domain
IPR027936Ephrin receptor, transmembrane domain

No MapMan annotations defined for this gene.