Gene: ENSMUSG00000032501 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000032501
Transcript Identifier
ENSMUST00000067543
Gene Type
Coding gene
Location
15 : 59649163-59654701 : positive

Family Information

Homologous gene family
HOM03P000001
(4368 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P069060
(2 genes in 2 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
tribbles homolog 1 (Drosophila)

Identifiers

Type Value
UniprotQ8K4K4
MGI2443397

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006469
ISO
IEA
Genome Projectnegative regulation of protein kinase activity
GO:0007254
ISO
Genome ProjectJNK cascade
GO:0014912
ISO
IEA
Genome Projectnegative regulation of smooth muscle cell migration
GO:0031665
ISO
IEA
Genome Projectnegative regulation of lipopolysaccharide-mediated signaling pathway
GO:0032436
IDA
Genome Projectpositive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032496
IMP
ISO
IEA
Genome Projectresponse to lipopolysaccharide
GO:0043405
ISS, ISO, IBA
IEA
Genome Projectregulation of MAP kinase activity
GO:0043433
IDA
ISO
IEA
Genome Projectnegative regulation of sequence-specific DNA binding transcription factor activity
GO:0045645
IMP
Genome Projectpositive regulation of eosinophil differentiation
GO:0045651
IMP
Genome Projectpositive regulation of macrophage differentiation
GO:0045659
IMP
Genome Projectnegative regulation of neutrophil differentiation
GO:0048662
ISO
IEA
Genome Projectnegative regulation of smooth muscle cell proliferation
GO:0051443
IC
Genome Projectpositive regulation of ubiquitin-protein transferase activity
GO:1904030
ISO
Genome Projectnegative regulation of cyclin-dependent protein kinase activity
GO:0006468
TAS
Genome Projectprotein phosphorylation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004860
ISO
IEA
Genome Projectprotein kinase inhibitor activity
GO:0008134
IDA, IPI
ISO
IEA
Genome Projecttranscription factor binding
GO:0031434
ISO, IBA
IEA
Genome Projectmitogen-activated protein kinase kinase binding
GO:0031625
IDA
Genome Projectubiquitin protein ligase binding
GO:0055106
IDA
Genome Projectubiquitin-protein transferase regulator activity
GO:0004672
TAS
Genome Projectprotein kinase activity
GO:0005524
TAS
Genome ProjectATP binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
ISO, IBA
IEA
Genome Projectnucleus
GO:0005737
ISO
IEA
Genome Projectcytoplasm

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000719Protein kinase domain
IPR011009Protein kinase-like domain
IPR024104Pseudokinase tribbles family/serine-threonine-protein kinase 40
IPR024105Tribbles homologue 1

No MapMan annotations defined for this gene.