Gene: ENSMUSG00000032405 (Mus musculus)

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Gene Identifier
ENSMUSG00000032405
Transcript Identifier
ENSMUST00000098651
Gene Type
Coding gene
Location
9 : 62881968-62980871 : negative

Family Information

Homologous gene family
HOM03P006281
(14 genes in 11 species)
specific family
Orthologous gene family
ORTHO03P015509
(6 genes in 4 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
protein inhibitor of activated STAT 1

Identifiers

Type Value
UniprotO88907
UniprotQ2M4G9
MGI1913125

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
IMP
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0007259
ISA
Genome ProjectJAK-STAT cascade
GO:0016925
IDA
ISO
IEA
Genome Projectprotein sumoylation
GO:0032436
IMP
Genome Projectpositive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0033235
ISS, ISO
IEA
Genome Projectpositive regulation of protein sumoylation
GO:0042127
IMP
Genome Projectregulation of cell proliferation
GO:0045444
IDA
Genome Projectfat cell differentiation
GO:1903507
ISA
Genome Projectnegative regulation of nucleic acid-templated transcription

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003677
IEA
Genome ProjectDNA binding
GO:0003714
ISA
Genome Projecttranscription corepressor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008134
IPI
Genome Projecttranscription factor binding
GO:0008270
IEA
Genome Projectzinc ion binding
GO:0016874
IEA
Genome Projectligase activity
GO:0019789
IEA
Genome ProjectSUMO transferase activity
GO:0019899
ISO
IEA
Genome Projectenzyme binding
GO:0031625
IPI
Genome Projectubiquitin protein ligase binding
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0061665
ISO
IEA
Genome ProjectSUMO ligase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
ISO
IEA
Genome Projectnucleus
GO:0016605
IDA
IEA
Genome ProjectPML body
GO:0016607
IEA
Genome Projectnuclear speck

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR003034SAP domain
IPR004181Zinc finger, MIZ-type
IPR023321PINIT domain
IPR027227E3 SUMO-protein ligase PIAS1

No MapMan annotations defined for this gene.