Gene: ENSMUSG00000032356 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000032356
Transcript Identifier
ENSMUST00000034912
Gene Type
Coding gene
Location
9 : 89909998-90026763 : positive

Family Information

Homologous gene family
HOM03P001034
(60 genes in 9 species)
specific family
Orthologous gene family
ORTHO03P022277
(4 genes in 2 species)
specific family

Descriptions

gene_descr
RAS protein-specific guanine nucleotide-releasing factor 1

Identifiers

Type Value
UniprotP27671
UniprotB2RS27
MGI99694

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0007264
IEA
Genome Projectsmall GTPase mediated signal transduction
GO:0008283
IMP
Genome Projectcell proliferation
GO:0035023
IEA
Genome Projectregulation of Rho protein signal transduction
GO:0035556
IEA
Genome Projectintracellular signal transduction
GO:0043547
IDA
IEA
Genome Projectpositive regulation of GTPase activity
GO:0046578
IDA
IEA
Genome Projectregulation of Ras protein signal transduction
GO:0048168
IMP
Genome Projectregulation of neuronal synaptic plasticity
GO:2000310
IGI
Genome Projectregulation of N-methyl-D-aspartate selective glutamate receptor activity
GO:0031175
IDA
Genome Projectneuron projection development
GO:0035020
IDA
Genome Projectregulation of Rac protein signal transduction
GO:0046579
ISS
Genome Projectpositive regulation of Ras protein signal transduction
GO:0048167
ISS
Genome Projectregulation of synaptic plasticity
GO:0090630
IDA
Genome Projectactivation of GTPase activity

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005085
IEA
Genome Projectguanyl-nucleotide exchange factor activity
GO:0005089
IEA
Genome ProjectRho guanyl-nucleotide exchange factor activity
GO:0035254
IPI
Genome Projectglutamate receptor binding
GO:0005515
IPI
Genome Projectprotein binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005622
IEA
Genome Projectintracellular
GO:0005829
IDA
Genome Projectcytosol
GO:0030426
IDA
Genome Projectgrowth cone

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000048IQ motif, EF-hand binding site
IPR000219Dbl homology (DH) domain
IPR000651Ras-like guanine nucleotide exchange factor, N-terminal
IPR001331Guanine-nucleotide dissociation stimulator, CDC24, conserved site
IPR001849Pleckstrin homology domain
IPR001895Ras guanine-nucleotide exchange factors catalytic domain
IPR011993PH domain-like
IPR019804Ras guanine-nucleotide exchange factor, conserved site
IPR023578Ras guanine nucleotide exchange factor domain
IPR030745Ras-specific guanine nucleotide-releasing factor 1

No MapMan annotations defined for this gene.