Gene: ENSMUSG00000032193 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000032193
Transcript Identifier
ENSMUST00000034713
Gene Type
Coding gene
Location
9 : 21723778-21748176 : positive

Family Information

Homologous gene family
HOM03P001101
(58 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P011790
(7 genes in 4 species)
specific family

Descriptions

gene_descr
low density lipoprotein receptor

Identifiers

Type Value
UniprotP35951
MGI96765

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006629
IGI
IEA
Genome Projectlipid metabolic process
GO:0006810
IEA
Genome Projecttransport
GO:0006869
IEA
Genome Projectlipid transport
GO:0006897
IEA
Genome Projectendocytosis
GO:0006898
IDA, IMP
ISO
IEA
Genome Projectreceptor-mediated endocytosis
GO:0008202
IEA
Genome Projectsteroid metabolic process
GO:0008203
IMP
IEA
Genome Projectcholesterol metabolic process
GO:0010867
IMP
Genome Projectpositive regulation of triglyceride biosynthetic process
GO:0010899
IMP
Genome Projectregulation of phosphatidylcholine catabolic process
GO:0015914
IMP
Genome Projectphospholipid transport
GO:0030299
ISO
IEA
Genome Projectintestinal cholesterol absorption
GO:0030301
IMP
ISO
IEA
Genome Projectcholesterol transport
GO:0034383
IMP
ISO
IEA
Genome Projectlow-density lipoprotein particle clearance
GO:0042157
IGI
Genome Projectlipoprotein metabolic process
GO:0042159
IDA, IMP
Genome Projectlipoprotein catabolic process
GO:0042632
IMP, IGI
ISO
IEA
Genome Projectcholesterol homeostasis
GO:0070508
IMP
Genome Projectcholesterol import
GO:2000188
IMP
Genome Projectregulation of cholesterol homeostasis

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001948
ISO
IEA
Genome Projectglycoprotein binding
GO:0005041
IDA, IMP
ISO
IEA
Genome Projectlow-density lipoprotein receptor activity
GO:0005509
IEA
Genome Projectcalcium ion binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0030169
IDA
Genome Projectlow-density lipoprotein particle binding
GO:0030229
IDA
ISO
IEA
Genome Projectvery-low-density lipoprotein particle receptor activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005764
ISS, ISO
IEA
Genome Projectlysosome
GO:0005768
IDA
IEA
Genome Projectendosome
GO:0005769
ISS, ISO
IEA
Genome Projectearly endosome
GO:0005770
ISS, ISO
IEA
Genome Projectlate endosome
GO:0005794
ISS, ISO
IEA
Genome ProjectGolgi apparatus
GO:0005886
TAS, IEA
Genome Projectplasma membrane
GO:0005905
ISO
IEA
Genome Projectcoated pit
GO:0009897
ISO
IEA
Genome Projectexternal side of plasma membrane
GO:0009986
IDA
ISS, ISO
IEA
Genome Projectcell surface
GO:0012505
IEA
Genome Projectendomembrane system
GO:0016020
ISO
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0016323
IDA
Genome Projectbasolateral plasma membrane
GO:0034362
IEA
Genome Projectlow-density lipoprotein particle
GO:0043235
ISO
IEA
Genome Projectreceptor complex
GO:0045177
IDA
Genome Projectapical part of cell
GO:1990666
ISS, ISO
Genome ProjectPCSK9-LDLR complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000033LDLR class B repeat
IPR000152EGF-type aspartate/asparagine hydroxylation site
IPR000742EGF-like domain
IPR001881EGF-like calcium-binding domain
IPR002172Low-density lipoprotein (LDL) receptor class A repeat
IPR009030Growth factor receptor cysteine-rich domain
IPR011042Six-bladed beta-propeller, TolB-like
IPR013032EGF-like, conserved site
IPR018097EGF-like calcium-binding, conserved site
IPR023415Low-density lipoprotein (LDL) receptor class A, conserved site

No MapMan annotations defined for this gene.