Gene: ENSMUSG00000032093 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000032093
Transcript Identifier
ENSMUST00000102832
Gene Type
Coding gene
Location
9 : 44999531-45009396 : negative

Family Information

Homologous gene family
HOM03P043035
(2 genes in 2 species)
specific family

Descriptions

gene_descr
CD3 antigen, epsilon polypeptide

Identifiers

Type Value
UniprotP22646
UniprotA6H6M1
MGI88332

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002669
IDA
Genome Projectpositive regulation of T cell anergy
GO:0007166
IDA
IEA
Genome Projectcell surface receptor signaling pathway
GO:0007584
IEA
Genome Projectresponse to nutrient
GO:0010628
ISO
Genome Projectpositive regulation of gene expression
GO:0010629
ISO
Genome Projectnegative regulation of gene expression
GO:0031295
IGI
Genome ProjectT cell costimulation
GO:0032729
IDA
Genome Projectpositive regulation of interferon-gamma production
GO:0032753
IDA
Genome Projectpositive regulation of interleukin-4 production
GO:0033077
IEA
Genome ProjectT cell differentiation in thymus
GO:0042102
IDA
ISO
IEA
Genome Projectpositive regulation of T cell proliferation
GO:0045060
IDA
Genome Projectnegative thymic T cell selection
GO:0045086
IDA
Genome Projectpositive regulation of interleukin-2 biosynthetic process
GO:0045879
IDA
Genome Projectnegative regulation of smoothened signaling pathway
GO:0046641
IDA
Genome Projectpositive regulation of alpha-beta T cell proliferation
GO:0046649
IMP
Genome Projectlymphocyte activation
GO:0050731
IDA
Genome Projectpositive regulation of peptidyl-tyrosine phosphorylation
GO:0050850
IDA
Genome Projectpositive regulation of calcium-mediated signaling
GO:0050852
IDA
Genome ProjectT cell receptor signaling pathway
GO:0050870
IDA
Genome Projectpositive regulation of T cell activation
GO:0097190
IDA
Genome Projectapoptotic signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004871
IDA
Genome Projectsignal transducer activity
GO:0004888
IEA
Genome Projecttransmembrane signaling receptor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0017124
ISO
IEA
Genome ProjectSH3 domain binding
GO:0046982
ISO
IEA
Genome Projectprotein heterodimerization activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001772
IDA
Genome Projectimmunological synapse
GO:0005886
ISO
IEA
Genome Projectplasma membrane
GO:0005911
IDA
Genome Projectcell-cell junction
GO:0009897
IDA
ISO
IEA
Genome Projectexternal side of plasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0042101
ISO
IEA
Genome ProjectT cell receptor complex
GO:0042105
IDA
Genome Projectalpha-beta T cell receptor complex
GO:0016021
IEA
Genome Projectintegral component of membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR003110Phosphorylated immunoreceptor signalling ITAM
IPR003598Immunoglobulin subtype 2
IPR007110Immunoglobulin-like domain
IPR013783Immunoglobulin-like fold
IPR015484CD3 protein, epsilon/gamma/delta subunit

No MapMan annotations defined for this gene.