Gene: ENSMUSG00000032041 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000032041
Transcript Identifier
ENSMUST00000176685
Gene Type
Coding gene
Location
9 : 35187911-35191108 : negative

Family Information

Homologous gene family
HOM03P043586
(2 genes in 2 species)
specific family

Descriptions

gene_descr
toll-interleukin 1 receptor (TIR) domain-containing adaptor protein

Identifiers

Type Value
UniprotH3BKL1
MGI2152213

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0007165
IEA
Genome Projectsignal transduction
GO:0007166
IPI
ISO
Genome Projectcell surface receptor signaling pathway
GO:0007249
IMP
ISO
Genome ProjectI-kappaB kinase/NF-kappaB signaling
GO:0007257
ISO
Genome Projectactivation of JUN kinase activity
GO:0009617
ISO
Genome Projectresponse to bacterium
GO:0030099
IMP
Genome Projectmyeloid cell differentiation
GO:0032496
ISO
IEA
Genome Projectresponse to lipopolysaccharide
GO:0032738
ISO
IEA
Genome Projectpositive regulation of interleukin-15 production
GO:0032757
ISO
IEA
Genome Projectpositive regulation of interleukin-8 production
GO:0032760
IMP
ISO
IEA
Genome Projectpositive regulation of tumor necrosis factor production
GO:0034137
ISO
IEA
Genome Projectpositive regulation of toll-like receptor 2 signaling pathway
GO:0034145
ISO
IEA
Genome Projectpositive regulation of toll-like receptor 4 signaling pathway
GO:0035665
ISO
IEA
Genome ProjectTIRAP-dependent toll-like receptor 4 signaling pathway
GO:0043123
ISO
IEA
Genome Projectpositive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0044130
IMP
Genome Projectnegative regulation of growth of symbiont in host
GO:0045410
ISO
IEA
Genome Projectpositive regulation of interleukin-6 biosynthetic process
GO:0046330
ISO
IEA
Genome Projectpositive regulation of JNK cascade
GO:0050830
IMP
Genome Projectdefense response to Gram-positive bacterium
GO:0051092
ISO
IEA
Genome Projectpositive regulation of NF-kappaB transcription factor activity
GO:0070374
ISO
IEA
Genome Projectpositive regulation of ERK1 and ERK2 cascade
GO:0070935
ISO
IEA
Genome Project3'-UTR-mediated mRNA stabilization
GO:0071221
IMP
Genome Projectcellular response to bacterial lipopeptide
GO:0071223
IMP
Genome Projectcellular response to lipoteichoic acid
GO:0090073
ISO
IEA
Genome Projectpositive regulation of protein homodimerization activity

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005080
ISO
IEA
Genome Projectprotein kinase C binding
GO:0035662
ISO
IEA
Genome ProjectToll-like receptor 4 binding
GO:0035663
ISO
IEA
Genome ProjectToll-like receptor 2 binding
GO:0046982
ISO
IEA
Genome Projectprotein heterodimerization activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005654
ISO
IEA
Genome Projectnucleoplasm
GO:0005737
ISO
IEA
Genome Projectcytoplasm
GO:0005886
ISO
IEA
Genome Projectplasma membrane
GO:0045171
ISO
IEA
Genome Projectintercellular bridge

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000157Toll/interleukin-1 receptor homology (TIR) domain
IPR017279Toll-interleukin 1 receptor domain-containing adaptor protein, Tirap

No MapMan annotations defined for this gene.