Gene: ENSMUSG00000031987 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000031987
Transcript Identifier
ENSMUST00000034469
Gene Type
Coding gene
Location
8 : 124910708-124949054 : negative

Family Information

Homologous gene family
HOM03P003570
(27 genes in 15 species)
specific family
Orthologous gene family
ORTHO03P028606
(4 genes in 4 species)
specific family

Descriptions

gene_descr
egl-9 family hypoxia-inducible factor 1

Identifiers

Type Value
UniprotQ91YE3
MGI1932286

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001666
ISO
IEA
Genome Projectresponse to hypoxia
GO:0018401
ISO
IEA
Genome Projectpeptidyl-proline hydroxylation to 4-hydroxy-L-proline
GO:0032364
ISO
IEA
Genome Projectoxygen homeostasis
GO:0043433
ISO
IEA
Genome Projectnegative regulation of sequence-specific DNA binding transcription factor activity
GO:0045765
IMP
Genome Projectregulation of angiogenesis
GO:0055008
IMP
Genome Projectcardiac muscle tissue morphogenesis
GO:0055114
IEA
Genome Projectoxidation-reduction process
GO:0060347
IMP
Genome Projectheart trabecula formation
GO:0060412
IMP
Genome Projectventricular septum morphogenesis
GO:0060711
IMP
Genome Projectlabyrinthine layer development
GO:0071731
ISS, ISO
IEA
Genome Projectresponse to nitric oxide

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005506
IEA
Genome Projectiron ion binding
GO:0016491
IEA
Genome Projectoxidoreductase activity
GO:0016705
IEA
Genome Projectoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0016706
ISO
IEA
Genome Projectoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0031418
IEA
Genome ProjectL-ascorbic acid binding
GO:0031545
ISO
IEA
Genome Projectpeptidyl-proline 4-dioxygenase activity
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0051213
IEA
Genome Projectdioxygenase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IEA
Genome Projectnucleus
GO:0005737
ISO
IEA
Genome Projectcytoplasm

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR002893Zinc finger, MYND-type
IPR005123Oxoglutarate/iron-dependent dioxygenase
IPR006620Prolyl 4-hydroxylase, alpha subunit

No MapMan annotations defined for this gene.