Gene: ENSMUSG00000031980 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000031980
Transcript Identifier
ENSMUST00000063278
Gene Type
Coding gene
Location
8 : 124556930-124564566 : negative

Family Information

Homologous gene family
HOM03P032465
(2 genes in 2 species)
specific family

Descriptions

gene_descr
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)

Identifiers

Type Value
UniprotQ3UTR7
MGI87963

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001543
IMP
Genome Projectovarian follicle rupture
GO:0001568
IMP
Genome Projectblood vessel development
GO:0001658
IDA
Genome Projectbranching involved in ureteric bud morphogenesis
GO:0001822
IMP
ISO
IEA
Genome Projectkidney development
GO:0001991
IMP
Genome Projectregulation of systemic arterial blood pressure by circulatory renin-angiotensin
GO:0001998
IDA
Genome Projectangiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure
GO:0001999
IMP
Genome Projectrenal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure
GO:0002018
IMP
IEA
Genome Projectrenin-angiotensin regulation of aldosterone production
GO:0002019
IMP
Genome Projectregulation of renal output by angiotensin
GO:0002027
IEA
Genome Projectregulation of heart rate
GO:0002035
IDA
Genome Projectbrain renin-angiotensin system
GO:0003014
ISO
IEA
Genome Projectrenal system process
GO:0003051
IEA
Genome Projectangiotensin-mediated drinking behavior
GO:0003081
IEA
Genome Projectregulation of systemic arterial blood pressure by renin-angiotensin
GO:0003331
IEA
Genome Projectpositive regulation of extracellular matrix constituent secretion
GO:0006883
IEA
Genome Projectcellular sodium ion homeostasis
GO:0007160
IMP
Genome Projectcell-matrix adhesion
GO:0007166
IEA
Genome Projectcell surface receptor signaling pathway
GO:0007186
ISO
IEA
Genome ProjectG-protein coupled receptor signaling pathway
GO:0007202
IEA
Genome Projectactivation of phospholipase C activity
GO:0007250
IDA
Genome Projectactivation of NF-kappaB-inducing kinase activity
GO:0007565
IEA
Genome Projectfemale pregnancy
GO:0007568
IEA
Genome Projectaging
GO:0007588
IMP
Genome Projectexcretion
GO:0008065
IMP
Genome Projectestablishment of blood-nerve barrier
GO:0008217
IMP
ISO
IEA
Genome Projectregulation of blood pressure
GO:0008284
IEA
Genome Projectpositive regulation of cell proliferation
GO:0008285
IMP
Genome Projectnegative regulation of cell proliferation
GO:0009409
IMP
Genome Projectresponse to cold
GO:0009651
IMP
Genome Projectresponse to salt stress
GO:0010468
IDA
Genome Projectregulation of gene expression
GO:0010535
ISO
IEA
Genome Projectpositive regulation of activation of JAK2 kinase activity
GO:0010595
ISO
IEA
Genome Projectpositive regulation of endothelial cell migration
GO:0010613
IEA
Genome Projectpositive regulation of cardiac muscle hypertrophy
GO:0010628
IDA
Genome Projectpositive regulation of gene expression
GO:0010873
ISO
IEA
Genome Projectpositive regulation of cholesterol esterification
GO:0010951
IBA
Genome Projectnegative regulation of endopeptidase activity
GO:0014061
IEA
Genome Projectregulation of norepinephrine secretion
GO:0014068
ISO
IEA
Genome Projectpositive regulation of phosphatidylinositol 3-kinase signaling
GO:0014824
IEA
Genome Projectartery smooth muscle contraction
GO:0014873
IEA
Genome Projectresponse to muscle activity involved in regulation of muscle adaptation
GO:0016525
IEA
Genome Projectnegative regulation of angiogenesis
GO:0030198
IMP
Genome Projectextracellular matrix organization
GO:0030308
IEA
Genome Projectnegative regulation of cell growth
GO:0030432
IMP
Genome Projectperistalsis
GO:0032270
ISO
IEA
Genome Projectpositive regulation of cellular protein metabolic process
GO:0032930
IEA
Genome Projectpositive regulation of superoxide anion generation
GO:0033138
IDA
Genome Projectpositive regulation of peptidyl-serine phosphorylation
GO:0034104
IEA
Genome Projectnegative regulation of tissue remodeling
GO:0035411
IEA
Genome Projectcatenin import into nucleus
GO:0035813
IEA
Genome Projectregulation of renal sodium excretion
GO:0035815
IEA
Genome Projectpositive regulation of renal sodium excretion
GO:0040018
IMP
Genome Projectpositive regulation of multicellular organism growth
GO:0042310
IEA
Genome Projectvasoconstriction
GO:0042311
IEA
Genome Projectvasodilation
GO:0042445
IMP
Genome Projecthormone metabolic process
GO:0042756
IMP
Genome Projectdrinking behavior
GO:0042981
IDA
Genome Projectregulation of apoptotic process
GO:0043085
IEA
Genome Projectpositive regulation of catalytic activity
GO:0043410
IMP
Genome Projectpositive regulation of MAPK cascade
GO:0043524
IMP
Genome Projectnegative regulation of neuron apoptotic process
GO:0045429
IEA
Genome Projectpositive regulation of nitric oxide biosynthetic process
GO:0045723
IMP
Genome Projectpositive regulation of fatty acid biosynthetic process
GO:0045742
ISO
IEA
Genome Projectpositive regulation of epidermal growth factor receptor signaling pathway
GO:0045777
IEA
Genome Projectpositive regulation of blood pressure
GO:0045893
ISO
IEA
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045909
IEA
Genome Projectpositive regulation of vasodilation
GO:0046622
IDA, IMP
Genome Projectpositive regulation of organ growth
GO:0048143
IMP
Genome Projectastrocyte activation
GO:0048144
IEA
Genome Projectfibroblast proliferation
GO:0048146
IEA
Genome Projectpositive regulation of fibroblast proliferation
GO:0048169
IEA
Genome Projectregulation of long-term neuronal synaptic plasticity
GO:0048659
IDA, IMP
IEA
Genome Projectsmooth muscle cell proliferation
GO:0050663
IEA
Genome Projectcytokine secretion
GO:0050727
IDA, IGI
Genome Projectregulation of inflammatory response
GO:0050731
ISO
IEA
Genome Projectpositive regulation of peptidyl-tyrosine phosphorylation
GO:0051145
IDA, IMP
Genome Projectsmooth muscle cell differentiation
GO:0051387
ISO
IEA
Genome Projectnegative regulation of neurotrophin TRK receptor signaling pathway
GO:0051403
IEA
Genome Projectstress-activated MAPK cascade
GO:0051924
IEA
Genome Projectregulation of calcium ion transport
GO:0051969
IEA
Genome Projectregulation of transmission of nerve impulse
GO:0061049
IEA
Genome Projectcell growth involved in cardiac muscle cell development
GO:0061098
ISO
IEA
Genome Projectpositive regulation of protein tyrosine kinase activity
GO:0070371
IEA
Genome ProjectERK1 and ERK2 cascade
GO:0070471
IEA
Genome Projectuterine smooth muscle contraction
GO:0071260
IEA
Genome Projectcellular response to mechanical stimulus
GO:0090190
ISO
IEA
Genome Projectpositive regulation of branching involved in ureteric bud morphogenesis
GO:1900020
IDA
Genome Projectpositive regulation of protein kinase C activity
GO:1901201
ISO
IEA
Genome Projectregulation of extracellular matrix assembly
GO:1902632
ISO
IEA
Genome Projectpositive regulation of membrane hyperpolarization
GO:1903598
ISO
IEA
Genome Projectpositive regulation of gap junction assembly
GO:1903779
ISO
IEA
Genome Projectregulation of cardiac conduction
GO:2001238
ISO
IEA
Genome Projectpositive regulation of extrinsic apoptotic signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004867
IBA
Genome Projectserine-type endopeptidase inhibitor activity
GO:0005179
IEA
Genome Projecthormone activity
GO:0017080
ISO
IEA
Genome Projectsodium channel regulator activity
GO:0031701
IEA
Genome Projectangiotensin receptor binding
GO:0031702
IDA
ISO
IEA
Genome Projecttype 1 angiotensin receptor binding
GO:0031703
IPI
ISO
IEA
Genome Projecttype 2 angiotensin receptor binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005615
IDA
ISO
IEA
Genome Projectextracellular space
GO:0005737
IEA
Genome Projectcytoplasm
GO:0070062
ISO
IEA
Genome Projectextracellular exosome
GO:0072562
ISO
IEA
Genome Projectblood microparticle

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000215Serpin family
IPR000227Angiotensinogen
IPR023796Serpin domain

No MapMan annotations defined for this gene.