Gene: ENSMUSG00000031928 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000031928
Transcript Identifier
ENSMUST00000034405
Gene Type
Coding gene
Location
9 : 14785509-14833663 : positive

Family Information

Homologous gene family
HOM03P002003
(42 genes in 39 species)
specific family

Descriptions

gene_descr
meiotic recombination 11 homolog A (S. cerevisiae)

Identifiers

Type Value
UniprotQ61216
UniprotQ3URU4
MGI1100512

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000723
IBA
Genome Projecttelomere maintenance
GO:0006259
IEA
Genome ProjectDNA metabolic process
GO:0006281
IEA
Genome ProjectDNA repair
GO:0006284
IBA
Genome Projectbase-excision repair
GO:0006302
IMP
IEA
Genome Projectdouble-strand break repair
GO:0006303
ISO
IEA
Genome Projectdouble-strand break repair via nonhomologous end joining
GO:0006974
ISO
IEA
Genome Projectcellular response to DNA damage stimulus
GO:0007062
ISO
IEA
Genome Projectsister chromatid cohesion
GO:0007095
IMP
Genome Projectmitotic G2 DNA damage checkpoint
GO:0007129
IMP
Genome Projectsynapsis
GO:0007507
IEA
Genome Projectheart development
GO:0008283
IMP
Genome Projectcell proliferation
GO:0031573
IMP
Genome Projectintra-S DNA damage checkpoint
GO:0031954
ISO
IEA
Genome Projectpositive regulation of protein autophosphorylation
GO:0032508
ISO
IEA
Genome ProjectDNA duplex unwinding
GO:0032876
ISO
IEA
Genome Projectnegative regulation of DNA endoreduplication
GO:0033674
ISO
IEA
Genome Projectpositive regulation of kinase activity
GO:0046597
IEA
Genome Projectnegative regulation of viral entry into host cell
GO:0051276
IMP
Genome Projectchromosome organization
GO:0051321
IEA
Genome Projectmeiotic cell cycle
GO:0090305
ISO
Genome Projectnucleic acid phosphodiester bond hydrolysis

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000014
ISO
IEA
Genome Projectsingle-stranded DNA endodeoxyribonuclease activity
GO:0003677
ISO
IEA
Genome ProjectDNA binding
GO:0004003
ISO
IEA
Genome ProjectATP-dependent DNA helicase activity
GO:0004518
IEA
Genome Projectnuclease activity
GO:0004519
IBA
IEA
Genome Projectendonuclease activity
GO:0004520
ISO
IEA
Genome Projectendodeoxyribonuclease activity
GO:0004527
IEA
Genome Projectexonuclease activity
GO:0008022
ISO
IEA
Genome Projectprotein C-terminus binding
GO:0008408
ISO, IBA
Genome Project3'-5' exonuclease activity
GO:0016787
IEA
Genome Projecthydrolase activity
GO:0030145
IEA
Genome Projectmanganese ion binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000781
ISO
IEA
Genome Projectchromosome, telomeric region
GO:0000785
IBA
Genome Projectchromatin
GO:0000790
IEA
Genome Projectnuclear chromatin
GO:0000794
IEA
Genome Projectcondensed nuclear chromosome
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005654
ISO
IEA
Genome Projectnucleoplasm
GO:0030870
ISO, IBA
Genome ProjectMre11 complex
GO:0035861
ISO, IBA
IEA
Genome Projectsite of double-strand break
GO:0048471
IEA
Genome Projectperinuclear region of cytoplasm

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR003701DNA double-strand break repair protein Mre11
IPR004843Calcineurin-like phosphoesterase domain, apaH type
IPR007281Mre11, DNA-binding
IPR029052Metallo-dependent phosphatase-like

No MapMan annotations defined for this gene.