Gene: ENSMUSG00000031760 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000031760
Transcript Identifier
ENSMUST00000034211
Gene Type
Coding gene
Location
8 : 94152800-94154010 : positive

Family Information

Homologous gene family
HOM03P027106
(3 genes in 2 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
metallothionein 3

Identifiers

Type Value
UniprotP28184
UniprotQ3USP9
MGI97173

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000060
ISS
IEA
Genome Projectprotein import into nucleus, translocation
GO:0001666
ISS
IEA
Genome Projectresponse to hypoxia
GO:0001934
ISS
IEA
Genome Projectpositive regulation of protein phosphorylation
GO:0006112
IMP
Genome Projectenergy reserve metabolic process
GO:0006707
IMP
Genome Projectcholesterol catabolic process
GO:0006829
IDA
Genome Projectzinc II ion transport
GO:0006875
IDA
Genome Projectcellular metal ion homeostasis
GO:0006882
IDA, IMP
Genome Projectcellular zinc ion homeostasis
GO:0006979
IMP
Genome Projectresponse to oxidative stress
GO:0007420
IEA
Genome Projectbrain development
GO:0010507
IMP
Genome Projectnegative regulation of autophagy
GO:0010628
IMP
Genome Projectpositive regulation of gene expression
GO:0010940
ISS
IEA
Genome Projectpositive regulation of necrotic cell death
GO:0010942
IMP
Genome Projectpositive regulation of cell death
GO:0014002
IDA
Genome Projectastrocyte development
GO:0016570
ISS
IEA
Genome Projecthistone modification
GO:0019430
ISS
IEA
Genome Projectremoval of superoxide radicals
GO:0030308
ISS
IEA
Genome Projectnegative regulation of cell growth
GO:0030517
ISS
IEA
Genome Projectnegative regulation of axon extension
GO:0030949
ISS
IEA
Genome Projectpositive regulation of vascular endothelial growth factor receptor signaling pathway
GO:0032095
IMP
Genome Projectregulation of response to food
GO:0032148
ISS
IEA
Genome Projectactivation of protein kinase B activity
GO:0033210
IMP
Genome Projectleptin-mediated signaling pathway
GO:0034599
IDA
IEA
Genome Projectcellular response to oxidative stress
GO:0035690
ISS
IEA
Genome Projectcellular response to drug
GO:0036091
ISS
IEA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter in response to oxidative stress
GO:0043066
IMP
IEA
Genome Projectnegative regulation of apoptotic process
GO:0043085
IMP
Genome Projectpositive regulation of catalytic activity
GO:0043154
ISS
IEA
Genome Projectnegative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043491
ISS
IEA
Genome Projectprotein kinase B signaling
GO:0043524
IDA
Genome Projectnegative regulation of neuron apoptotic process
GO:0044242
IMP
Genome Projectcellular lipid catabolic process
GO:0045892
IMP
Genome Projectnegative regulation of transcription, DNA-templated
GO:0045893
IMP
Genome Projectpositive regulation of transcription, DNA-templated
GO:0050768
IDA
Genome Projectnegative regulation of neurogenesis
GO:0050821
ISS
IEA
Genome Projectprotein stabilization
GO:0051354
ISS
IEA
Genome Projectnegative regulation of oxidoreductase activity
GO:0055069
ISS
IEA
Genome Projectzinc ion homeostasis
GO:0055073
IMP
IEA
Genome Projectcadmium ion homeostasis
GO:0060049
IMP
Genome Projectregulation of protein glycosylation
GO:0060547
IMP
Genome Projectnegative regulation of necrotic cell death
GO:0070371
ISS
IEA
Genome ProjectERK1 and ERK2 cascade
GO:0070374
IMP
Genome Projectpositive regulation of ERK1 and ERK2 cascade
GO:0071276
ISS
IEA
Genome Projectcellular response to cadmium ion
GO:0071456
IEA
Genome Projectcellular response to hypoxia
GO:0071732
ISS
IEA
Genome Projectcellular response to nitric oxide
GO:0097214
IMP
Genome Projectpositive regulation of lysosomal membrane permeability
GO:1901215
IEA
Genome Projectnegative regulation of neuron death
GO:2000117
ISS
IEA
Genome Projectnegative regulation of cysteine-type endopeptidase activity
GO:2000296
IEA
Genome Projectnegative regulation of hydrogen peroxide catabolic process
GO:2000376
IMP
Genome Projectpositive regulation of oxygen metabolic process
GO:2000378
ISS
IEA
Genome Projectnegative regulation of reactive oxygen species metabolic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005507
ISS
IEA
Genome Projectcopper ion binding
GO:0008144
ISS
IEA
Genome Projectdrug binding
GO:0008270
IDA
IC, IEA
Genome Projectzinc ion binding
GO:0030295
ISS
IEA
Genome Projectprotein kinase activator activity
GO:0043027
ISS
IEA
Genome Projectcysteine-type endopeptidase inhibitor activity involved in apoptotic process
GO:0046870
ISS
IEA
Genome Projectcadmium ion binding
GO:0046872
IDA
IEA
Genome Projectmetal ion binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005615
IEA
Genome Projectextracellular space
GO:0005622
ISS
IEA
Genome Projectintracellular
GO:0005634
ISS
Genome Projectnucleus
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005741
IEA
Genome Projectmitochondrial outer membrane
GO:0005791
IEA
Genome Projectrough endoplasmic reticulum
GO:0005840
IEA
Genome Projectribosome
GO:0005874
IEA
Genome Projectmicrotubule
GO:0005886
IEA
Genome Projectplasma membrane
GO:0008021
IDA
Genome Projectsynaptic vesicle
GO:0014069
IEA
Genome Projectpostsynaptic density
GO:0016234
ISS
IEA
Genome Projectinclusion body
GO:0030424
IEA
Genome Projectaxon
GO:0043197
IEA
Genome Projectdendritic spine
GO:0048471
ISS
IEA
Genome Projectperinuclear region of cytoplasm
GO:0097449
IEA
Genome Projectastrocyte projection
GO:0097450
IEA
Genome Projectastrocyte end-foot

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000006Metallothionein, vertebrate
IPR003019Metallothionein
IPR017854Metallothionein domain
IPR018064Metallothionein, vertebrate, metal binding site
IPR023587Metallothionein domain, vertebrate

No MapMan annotations defined for this gene.