Gene: ENSMUSG00000031639 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000031639
Transcript Identifier
ENSMUST00000167106
Gene Type
Coding gene
Location
8 : 45396913-45403141 : negative

Family Information

Homologous gene family
HOM03P004593
(20 genes in 3 species)
specific family

Descriptions

gene_descr
toll-like receptor 3

Identifiers

Type Value
UniprotQ99MB1
MGI2156367

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001819
IEA
Genome Projectpositive regulation of cytokine production
GO:0002376
IEA
Genome Projectimmune system process
GO:0002730
IDA
Genome Projectregulation of dendritic cell cytokine production
GO:0002756
IEA
Genome ProjectMyD88-independent toll-like receptor signaling pathway
GO:0006952
IMP
Genome Projectdefense response
GO:0006954
IEA
Genome Projectinflammatory response
GO:0007165
IEA
Genome Projectsignal transduction
GO:0007252
ISO
IEA
Genome ProjectI-kappaB phosphorylation
GO:0009615
IMP
Genome Projectresponse to virus
GO:0010628
ISO
Genome Projectpositive regulation of gene expression
GO:0032481
IDA
Genome Projectpositive regulation of type I interferon production
GO:0032722
ISO
IEA
Genome Projectpositive regulation of chemokine production
GO:0032728
IDA
Genome Projectpositive regulation of interferon-beta production
GO:0032735
IDA
Genome Projectpositive regulation of interleukin-12 production
GO:0032755
IDA, IMP
ISO
IEA
Genome Projectpositive regulation of interleukin-6 production
GO:0032757
ISO
IEA
Genome Projectpositive regulation of interleukin-8 production
GO:0032760
IDA, IMP
Genome Projectpositive regulation of tumor necrosis factor production
GO:0034123
ISO
IEA
Genome Projectpositive regulation of toll-like receptor signaling pathway
GO:0034138
IEA
Genome Projecttoll-like receptor 3 signaling pathway
GO:0034346
IDA
Genome Projectpositive regulation of type III interferon production
GO:0042346
ISO
IEA
Genome Projectpositive regulation of NF-kappaB import into nucleus
GO:0043123
IDA, IMP, IGI
Genome Projectpositive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043330
IMP
ISO
IEA
Genome Projectresponse to exogenous dsRNA
GO:0045078
ISS, ISO
IEA
Genome Projectpositive regulation of interferon-gamma biosynthetic process
GO:0045080
IMP
Genome Projectpositive regulation of chemokine biosynthetic process
GO:0045087
TAS, IEA
Genome Projectinnate immune response
GO:0045356
ISS, ISO
IEA
Genome Projectpositive regulation of interferon-alpha biosynthetic process
GO:0045359
ISS, ISO
IEA
Genome Projectpositive regulation of interferon-beta biosynthetic process
GO:0045944
IDA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0046330
IDA
Genome Projectpositive regulation of JNK cascade
GO:0050729
IEA
Genome Projectpositive regulation of inflammatory response
GO:0051092
IMP
Genome Projectpositive regulation of NF-kappaB transcription factor activity
GO:0051607
IGI
TAS, IEA
Genome Projectdefense response to virus
GO:0071260
IEA
Genome Projectcellular response to mechanical stimulus
GO:0097191
ISO
IEA
Genome Projectextrinsic apoptotic signaling pathway
GO:0097527
ISO
IEA
Genome Projectnecroptotic signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003723
IEA
Genome ProjectRNA binding
GO:0003725
ISS, ISO
IEA
Genome Projectdouble-stranded RNA binding
GO:0004888
IEA
Genome Projecttransmembrane signaling receptor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0042802
ISO
IEA
Genome Projectidentical protein binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005622
ISO
Genome Projectintracellular
GO:0005737
ISO
IEA
Genome Projectcytoplasm
GO:0005765
ISO
IEA
Genome Projectlysosomal membrane
GO:0005768
IEA
Genome Projectendosome
GO:0005783
IEA
Genome Projectendoplasmic reticulum
GO:0005789
IEA
Genome Projectendoplasmic reticulum membrane
GO:0010008
IEA
Genome Projectendosome membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000157Toll/interleukin-1 receptor homology (TIR) domain
IPR000372Leucine-rich repeat N-terminal domain
IPR000483Cysteine-rich flanking region, C-terminal
IPR001611Leucine-rich repeat
IPR003591Leucine-rich repeat, typical subtype
IPR027173Toll-like receptor 3

No MapMan annotations defined for this gene.