Gene: ENSMUSG00000031558 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000031558
Transcript Identifier
ENSMUST00000174421
Gene Type
Coding gene
Location
5 : 47985040-48304241 : positive

Family Information

Homologous gene family
HOM03P000383
(115 genes in 8 species)
specific family
Orthologous gene family
ORTHO03P011955
(7 genes in 3 species)
specific family

Descriptions

gene_descr
slit homolog 2 (Drosophila)

Identifiers

Type Value
UniprotG3UYX7
MGI1315205

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001656
IMP
Genome Projectmetanephros development
GO:0001657
ISO
IEA
Genome Projectureteric bud development
GO:0001701
IMP
Genome Projectin utero embryonic development
GO:0001933
ISO
IEA
Genome Projectnegative regulation of protein phosphorylation
GO:0002042
ISO
IEA
Genome Projectcell migration involved in sprouting angiogenesis
GO:0002689
ISO
IEA
Genome Projectnegative regulation of leukocyte chemotaxis
GO:0007409
IDA, IMP
Genome Projectaxonogenesis
GO:0007411
IDA, IMP, IGI
ISO
IEA
Genome Projectaxon guidance
GO:0007420
IEA
Genome Projectbrain development
GO:0008045
ISO
IEA
Genome Projectmotor neuron axon guidance
GO:0008285
IGI
Genome Projectnegative regulation of cell proliferation
GO:0010593
ISO
IEA
Genome Projectnegative regulation of lamellipodium assembly
GO:0010596
ISO
IEA
Genome Projectnegative regulation of endothelial cell migration
GO:0010629
IGI
Genome Projectnegative regulation of gene expression
GO:0014912
ISO
IEA
Genome Projectnegative regulation of smooth muscle cell migration
GO:0016337
IMP, IGI
Genome Projectsingle organismal cell-cell adhesion
GO:0021510
IEA
Genome Projectspinal cord development
GO:0021772
IGI
Genome Projectolfactory bulb development
GO:0021836
ISO
IEA
Genome Projectchemorepulsion involved in postnatal olfactory bulb interneuron migration
GO:0021972
ISO
IEA
Genome Projectcorticospinal neuron axon guidance through spinal cord
GO:0022029
IGI
Genome Projecttelencephalon cell migration
GO:0030308
ISO
IEA
Genome Projectnegative regulation of cell growth
GO:0030336
ISO
IEA
Genome Projectnegative regulation of cell migration
GO:0030517
IDA
Genome Projectnegative regulation of axon extension
GO:0030837
ISO
IEA
Genome Projectnegative regulation of actin filament polymerization
GO:0031290
IMP, IGI
ISO
IEA
Genome Projectretinal ganglion cell axon guidance
GO:0031667
IEA
Genome Projectresponse to nutrient levels
GO:0032870
IEA
Genome Projectcellular response to hormone stimulus
GO:0033563
IMP, IGI
Genome Projectdorsal/ventral axon guidance
GO:0034260
ISO
Genome Projectnegative regulation of GTPase activity
GO:0035385
ISO
Genome ProjectRoundabout signaling pathway
GO:0043065
ISO
IEA
Genome Projectpositive regulation of apoptotic process
GO:0043086
IEA
Genome Projectnegative regulation of catalytic activity
GO:0043116
ISO
IEA
Genome Projectnegative regulation of vascular permeability
GO:0048754
ISO
IEA
Genome Projectbranching morphogenesis of an epithelial tube
GO:0048812
IMP, IGI
Genome Projectneuron projection morphogenesis
GO:0048846
ISO
IEA
Genome Projectaxon extension involved in axon guidance
GO:0050728
IEA
Genome Projectnegative regulation of inflammatory response
GO:0050919
IMP
ISO
IEA
Genome Projectnegative chemotaxis
GO:0050929
ISO
IEA
Genome Projectinduction of negative chemotaxis
GO:0051058
ISO
IEA
Genome Projectnegative regulation of small GTPase mediated signal transduction
GO:0051414
IEA
Genome Projectresponse to cortisol
GO:0060603
IMP, IGI
Genome Projectmammary gland duct morphogenesis
GO:0060763
IMP
Genome Projectmammary duct terminal end bud growth
GO:0061364
IEA
Genome Projectapoptotic process involved in luteolysis
GO:0070100
ISO
IEA
Genome Projectnegative regulation of chemokine-mediated signaling pathway
GO:0071504
ISO
IEA
Genome Projectcellular response to heparin
GO:0071672
ISO
IEA
Genome Projectnegative regulation of smooth muscle cell chemotaxis
GO:0071676
ISO
IEA
Genome Projectnegative regulation of mononuclear cell migration
GO:0090024
ISO
IEA
Genome Projectnegative regulation of neutrophil chemotaxis
GO:0090260
ISO
IEA
Genome Projectnegative regulation of retinal ganglion cell axon guidance
GO:0090288
ISO
IEA
Genome Projectnegative regulation of cellular response to growth factor stimulus

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005095
ISO
IEA
Genome ProjectGTPase inhibitor activity
GO:0005102
TAS
Genome Projectreceptor binding
GO:0005509
IEA
Genome Projectcalcium ion binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0008201
ISO
IEA
Genome Projectheparin binding
GO:0042802
ISO
IEA
Genome Projectidentical protein binding
GO:0042803
ISO
IEA
Genome Projectprotein homodimerization activity
GO:0043237
ISO
IEA
Genome Projectlaminin-1 binding
GO:0043394
ISO
IEA
Genome Projectproteoglycan binding
GO:0043395
IEA
Genome Projectheparan sulfate proteoglycan binding
GO:0045499
IMP
Genome Projectchemorepellent activity
GO:0048495
ISO
IEA
Genome ProjectRoundabout binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
IEA
Genome Projectextracellular region
GO:0005615
IDA
ISO
IEA
Genome Projectextracellular space
GO:0005737
ISO
IEA
Genome Projectcytoplasm
GO:0005886
IEA
Genome Projectplasma membrane
GO:0009986
ISO
IEA
Genome Projectcell surface
GO:0070062
ISO
IEA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000152EGF-type aspartate/asparagine hydroxylation site
IPR000372Leucine-rich repeat N-terminal domain
IPR000483Cysteine-rich flanking region, C-terminal
IPR000742EGF-like domain
IPR001611Leucine-rich repeat
IPR001791Laminin G domain
IPR001881EGF-like calcium-binding domain
IPR003591Leucine-rich repeat, typical subtype
IPR003645Follistatin-like, N-terminal
IPR006207Cystine knot, C-terminal
IPR013032EGF-like, conserved site
IPR013320Concanavalin A-like lectin/glucanase domain
IPR018097EGF-like calcium-binding, conserved site

No MapMan annotations defined for this gene.