Gene: ENSMUSG00000031511 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000031511
Transcript Identifier
ENSMUST00000110909
Gene Type
Coding gene
Location
8 : 11728252-11824719 : positive

Family Information

Homologous gene family
HOM03P010769
(7 genes in 5 species)
specific family

Descriptions

gene_descr
Rho guanine nucleotide exchange factor (GEF7)

Identifiers

Type Value
UniprotQ9ES28
MGI1860493

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002244
IGI
Genome Projecthematopoietic progenitor cell differentiation
GO:0007264
IEA
Genome Projectsmall GTPase mediated signal transduction
GO:0007399
IEA
Genome Projectnervous system development
GO:0010763
ISO
IEA
Genome Projectpositive regulation of fibroblast migration
GO:0030032
IMP
Genome Projectlamellipodium assembly
GO:0032092
IMP
Genome Projectpositive regulation of protein binding
GO:0035023
IEA
Genome Projectregulation of Rho protein signal transduction
GO:0035556
IEA
Genome Projectintracellular signal transduction
GO:0043065
ISS, ISO
IEA
Genome Projectpositive regulation of apoptotic process
GO:0043547
IMP
ISO
IEA
Genome Projectpositive regulation of GTPase activity
GO:0043615
IEA
Genome Projectastrocyte cell migration
GO:0048041
ISO
IEA
Genome Projectfocal adhesion assembly
GO:0060124
IMP
Genome Projectpositive regulation of growth hormone secretion
GO:1900026
ISO
IEA
Genome Projectpositive regulation of substrate adhesion-dependent cell spreading
GO:2000394
ISO
IEA
Genome Projectpositive regulation of lamellipodium morphogenesis

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005085
IDA
ISO
IEA
Genome Projectguanyl-nucleotide exchange factor activity
GO:0005089
IEA
Genome ProjectRho guanyl-nucleotide exchange factor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0019901
IPI
ISO
IEA
Genome Projectprotein kinase binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000322
IDA
Genome Projectstorage vacuole
GO:0001726
IEA
Genome Projectruffle
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005829
IDA
Genome Projectcytosol
GO:0005886
IDA
Genome Projectplasma membrane
GO:0005925
ISO
IEA
Genome Projectfocal adhesion
GO:0005938
IEA
Genome Projectcell cortex
GO:0030027
IDA
IEA
Genome Projectlamellipodium
GO:0030054
IEA
Genome Projectcell junction
GO:0030426
IEA
Genome Projectgrowth cone
GO:0042995
IEA
Genome Projectcell projection
GO:0043005
ISO
IEA
Genome Projectneuron projection
GO:0043025
ISO
IEA
Genome Projectneuronal cell body
GO:0043234
ISO
IEA
Genome Projectprotein complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000219Dbl homology (DH) domain
IPR001331Guanine-nucleotide dissociation stimulator, CDC24, conserved site
IPR001452SH3 domain
IPR001715Calponin homology domain
IPR001849Pleckstrin homology domain
IPR011511Variant SH3 domain
IPR011993PH domain-like
IPR032409Rho guanine nucleotide exchange factor, coiled-coil domain

No MapMan annotations defined for this gene.