Gene: ENSMUSG00000031451 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000031451
Transcript Identifier
ENSMUST00000033828
Gene Type
Coding gene
Location
8 : 13465746-13494339 : negative

Family Information

Homologous gene family
HOM03P000383
(115 genes in 8 species)
specific family
Orthologous gene family
ORTHO03P035166
(3 genes in 2 species)
specific family

Descriptions

gene_descr
growth arrest specific 6

Identifiers

Type Value
UniprotQ61592
MGI95660

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001764
IGI
Genome Projectneuron migration
GO:0001934
ISS, ISO
IEA
Genome Projectpositive regulation of protein phosphorylation
GO:0001961
ISS, ISO
IEA
Genome Projectpositive regulation of cytokine-mediated signaling pathway
GO:0003104
ISS
IEA
Genome Projectpositive regulation of glomerular filtration
GO:0006468
ISS, ISO
IEA
Genome Projectprotein phosphorylation
GO:0006909
ISS, ISO
IEA
Genome Projectphagocytosis
GO:0007165
ISO
IEA
Genome Projectsignal transduction
GO:0007167
IGI
Genome Projectenzyme linked receptor protein signaling pathway
GO:0007596
IMP
Genome Projectblood coagulation
GO:0009267
IDA
Genome Projectcellular response to starvation
GO:0010628
ISS, ISO
IEA
Genome Projectpositive regulation of gene expression
GO:0010804
ISS, ISO
IEA
Genome Projectnegative regulation of tumor necrosis factor-mediated signaling pathway
GO:0010934
IMP
Genome Projectmacrophage cytokine production
GO:0018105
ISS, ISO
IEA
Genome Projectpeptidyl-serine phosphorylation
GO:0019064
ISS, ISO
IEA
Genome Projectfusion of virus membrane with host plasma membrane
GO:0019079
ISS, ISO
IEA
Genome Projectviral genome replication
GO:0031100
IEA
Genome Projectorgan regeneration
GO:0031589
IMP
Genome Projectcell-substrate adhesion
GO:0032008
ISS
IEA
Genome Projectpositive regulation of TOR signaling
GO:0032148
ISS
IEA
Genome Projectactivation of protein kinase B activity
GO:0032689
ISS, ISO
IEA
Genome Projectnegative regulation of interferon-gamma production
GO:0032715
ISO
IEA
Genome Projectnegative regulation of interleukin-6 production
GO:0032720
ISS, ISO
IEA
Genome Projectnegative regulation of tumor necrosis factor production
GO:0032825
ISS, ISO
IEA
Genome Projectpositive regulation of natural killer cell differentiation
GO:0033138
ISS, ISO
IEA
Genome Projectpositive regulation of peptidyl-serine phosphorylation
GO:0033159
ISS, ISO
IEA
Genome Projectnegative regulation of protein import into nucleus, translocation
GO:0035457
ISS, ISO
IEA
Genome Projectcellular response to interferon-alpha
GO:0035690
ISS, ISO
IEA
Genome Projectcellular response to drug
GO:0035754
ISS, ISO
IEA
Genome ProjectB cell chemotaxis
GO:0040008
IEA
Genome Projectregulation of growth
GO:0043066
IDA, IMP, IGI
ISO
IEA
Genome Projectnegative regulation of apoptotic process
GO:0043154
ISS, ISO
IEA
Genome Projectnegative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043277
IDA
ISO
IEA
Genome Projectapoptotic cell clearance
GO:0043433
ISS, ISO
IEA
Genome Projectnegative regulation of sequence-specific DNA binding transcription factor activity
GO:0043491
IMP, IGI
ISO
IEA
Genome Projectprotein kinase B signaling
GO:0045860
ISS, ISO
IEA
Genome Projectpositive regulation of protein kinase activity
GO:0045892
ISS, ISO
IEA
Genome Projectnegative regulation of transcription, DNA-templated
GO:0046718
ISS, ISO
IEA
Genome Projectviral entry into host cell
GO:0046813
ISS, ISO
IEA
Genome Projectreceptor-mediated virion attachment to host cell
GO:0046827
ISS, ISO
IEA
Genome Projectpositive regulation of protein export from nucleus
GO:0048146
ISS, ISO
IEA
Genome Projectpositive regulation of fibroblast proliferation
GO:0050711
ISS, ISO
IEA
Genome Projectnegative regulation of interleukin-1 secretion
GO:0050766
ISS, ISO
IEA
Genome Projectpositive regulation of phagocytosis
GO:0051897
ISS, ISO
IEA
Genome Projectpositive regulation of protein kinase B signaling
GO:0061098
ISS, ISO
IEA
Genome Projectpositive regulation of protein tyrosine kinase activity
GO:0070168
ISS, ISO
IEA
Genome Projectnegative regulation of biomineral tissue development
GO:0070374
ISO
IEA
Genome Projectpositive regulation of ERK1 and ERK2 cascade
GO:0070588
ISO
IEA
Genome Projectcalcium ion transmembrane transport
GO:0071307
ISS, ISO
IEA
Genome Projectcellular response to vitamin K
GO:0071333
ISS
IEA
Genome Projectcellular response to glucose stimulus
GO:0071363
IDA, IMP
Genome Projectcellular response to growth factor stimulus
GO:0072661
ISS, ISO
IEA
Genome Projectprotein targeting to plasma membrane
GO:0085029
ISS
IEA
Genome Projectextracellular matrix assembly
GO:0097028
IEA
Genome Projectdendritic cell differentiation
GO:0097241
ISS, ISO
IEA
Genome Projecthematopoietic stem cell migration to bone marrow
GO:1900142
ISO
IEA
Genome Projectnegative regulation of oligodendrocyte apoptotic process
GO:1900165
ISS, ISO
IEA
Genome Projectnegative regulation of interleukin-6 secretion
GO:2000270
ISS, ISO
IEA
Genome Projectnegative regulation of fibroblast apoptotic process
GO:2000352
ISS, ISO
IEA
Genome Projectnegative regulation of endothelial cell apoptotic process
GO:2000510
ISO
IEA
Genome Projectpositive regulation of dendritic cell chemotaxis
GO:2000533
ISS
IEA
Genome Projectnegative regulation of renal albumin absorption
GO:2000669
ISS, ISO
IEA
Genome Projectnegative regulation of dendritic cell apoptotic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001786
ISS, ISO
IEA
Genome Projectphosphatidylserine binding
GO:0005102
ISS, ISO
IEA
Genome Projectreceptor binding
GO:0005245
ISS, ISO
IEA
Genome Projectvoltage-gated calcium channel activity
GO:0005509
IEA
Genome Projectcalcium ion binding
GO:0030296
ISS, ISO
IEA
Genome Projectprotein tyrosine kinase activator activity
GO:0030971
ISO
IEA
Genome Projectreceptor tyrosine kinase binding
GO:0043027
ISS, ISO
IEA
Genome Projectcysteine-type endopeptidase inhibitor activity involved in apoptotic process
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0048018
IDA
ISO
IEA
Genome Projectreceptor agonist activity
GO:0060090
ISS, ISO
IEA
Genome Projectbinding, bridging

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
IEA
Genome Projectextracellular region
GO:0005615
IDA
ISO
IEA
Genome Projectextracellular space
GO:0005622
IEA
Genome Projectintracellular
GO:0005737
ISS, ISO
IEA
Genome Projectcytoplasm
GO:0070062
ISO
IEA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000152EGF-type aspartate/asparagine hydroxylation site
IPR000294Gamma-carboxyglutamic acid-rich (GLA) domain
IPR000742EGF-like domain
IPR001791Laminin G domain
IPR001881EGF-like calcium-binding domain
IPR009030Growth factor receptor cysteine-rich domain
IPR013032EGF-like, conserved site
IPR013320Concanavalin A-like lectin/glucanase domain
IPR017857Coagulation factor, subgroup, Gla domain
IPR018097EGF-like calcium-binding, conserved site

No MapMan annotations defined for this gene.