Gene: ENSMUSG00000031446 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000031446
Transcript Identifier
ENSMUST00000016680
Gene Type
Coding gene
Location
8 : 13105756-13146627 : positive

Family Information

Homologous gene family
HOM03P000158
(196 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P001153
(40 genes in 35 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
cullin 4A

Identifiers

Type Value
UniprotQ3TCH7
MGI1914487

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001701
IMP
Genome Projectin utero embryonic development
GO:0006281
IEA
Genome ProjectDNA repair
GO:0006511
IMP
IEA
Genome Projectubiquitin-dependent protein catabolic process
GO:0006974
IEA
Genome Projectcellular response to DNA damage stimulus
GO:0008284
IDA
Genome Projectpositive regulation of cell proliferation
GO:0016032
IEA
Genome Projectviral process
GO:0016567
IEA
Genome Projectprotein ubiquitination
GO:0030097
IMP
Genome Projecthemopoiesis
GO:0030853
IDA
Genome Projectnegative regulation of granulocyte differentiation
GO:0035019
IMP
Genome Projectsomatic stem cell population maintenance
GO:0042787
IBA
Genome Projectprotein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0043161
IDA
Genome Projectproteasome-mediated ubiquitin-dependent protein catabolic process
GO:0045732
ISO
Genome Projectpositive regulation of protein catabolic process
GO:0051246
IMP
Genome Projectregulation of protein metabolic process
GO:1900087
IMP
Genome Projectpositive regulation of G1/S transition of mitotic cell cycle
GO:2000001
IMP
Genome Projectregulation of DNA damage checkpoint
GO:2000819
IMP
Genome Projectregulation of nucleotide-excision repair

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005515
IPI
Genome Projectprotein binding
GO:0031625
IEA
Genome Projectubiquitin protein ligase binding
GO:0061630
IBA
Genome Projectubiquitin protein ligase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0031461
IEA
Genome Projectcullin-RING ubiquitin ligase complex
GO:0031464
ISS, ISO, IBA
IEA
Genome ProjectCul4A-RING E3 ubiquitin ligase complex
GO:0080008
ISS, ISO
IEA
Genome ProjectCul4-RING E3 ubiquitin ligase complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001373Cullin, N-terminal
IPR011991Winged helix-turn-helix DNA-binding domain
IPR016157Cullin, conserved site
IPR016158Cullin homology
IPR016159Cullin repeat-like-containing domain
IPR019559Cullin protein, neddylation domain

No MapMan annotations defined for this gene.