Gene: ENSMUSG00000031284 (Mus musculus)

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Gene Identifier
ENSMUSG00000031284
Transcript Identifier
ENSMUST00000112863
Gene Type
Coding gene
Location
X : 143693314-143791324 : positive

Family Information

Homologous gene family
HOM03P000001
(4368 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P003220
(25 genes in 14 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
p21 protein (Cdc42/Rac)-activated kinase 3

Identifiers

Type Value
UniprotQ61036
MGI1339656

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000165
ISO
IEA
Genome ProjectMAPK cascade
GO:0000187
ISO
IEA
Genome Projectactivation of MAPK activity
GO:0006468
IEA
Genome Projectprotein phosphorylation
GO:0007266
IBA
Genome ProjectRho protein signal transduction
GO:0007275
IEA
Genome Projectmulticellular organismal development
GO:0007346
IBA
Genome Projectregulation of mitotic cell cycle
GO:0007409
IMP
Genome Projectaxonogenesis
GO:0008152
IEA
Genome Projectmetabolic process
GO:0010975
IEA
Genome Projectregulation of neuron projection development
GO:0016310
IEA
Genome Projectphosphorylation
GO:0016358
IMP
Genome Projectdendrite development
GO:0016477
IBA
Genome Projectcell migration
GO:0023014
IBA
Genome Projectsignal transduction by protein phosphorylation
GO:0030036
IBA
Genome Projectactin cytoskeleton organization
GO:0030833
ISS, ISO
IEA
Genome Projectregulation of actin filament polymerization
GO:0031098
IBA
Genome Projectstress-activated protein kinase signaling cascade
GO:0032147
IBA
Genome Projectactivation of protein kinase activity
GO:0042981
IBA
Genome Projectregulation of apoptotic process
GO:0043408
IBA
Genome Projectregulation of MAPK cascade
GO:0043525
IEA
Genome Projectpositive regulation of neuron apoptotic process
GO:0060996
IGI
Genome Projectdendritic spine development
GO:0061003
IEA
Genome Projectpositive regulation of dendritic spine morphogenesis
GO:0071407
IDA
Genome Projectcellular response to organic cyclic compound
GO:2000573
IEA
Genome Projectpositive regulation of DNA biosynthetic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0003824
IEA
Genome Projectcatalytic activity
GO:0004672
IDA
IEA
Genome Projectprotein kinase activity
GO:0004674
IBA
IEA
Genome Projectprotein serine/threonine kinase activity
GO:0004708
ISS, ISO
IEA
Genome ProjectMAP kinase kinase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005524
IEA
Genome ProjectATP binding
GO:0016301
IEA
Genome Projectkinase activity
GO:0016740
IEA
Genome Projecttransferase activity
GO:0017048
IPI
Genome ProjectRho GTPase binding
GO:0017124
IEA
Genome ProjectSH3 domain binding
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0048365
IBA
Genome ProjectRac GTPase binding
GO:0051020
IEA
Genome ProjectGTPase binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IBA
IEA
Genome Projectcytoplasm
GO:0005768
IEA
Genome Projectendosome
GO:0005829
TAS
Genome Projectcytosol

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000095CRIB domain
IPR000719Protein kinase domain
IPR002290Serine/threonine/dual specificity protein kinase, catalytic domain
IPR008271Serine/threonine-protein kinase, active site
IPR011009Protein kinase-like domain
IPR017441Protein kinase, ATP binding site

No MapMan annotations defined for this gene.