Gene: ENSMUSG00000031165 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000031165
Transcript Identifier
ENSMUST00000033505
Gene Type
Coding gene
Location
X : 8081934-8090428 : negative

Family Information

Homologous gene family
HOM03P007790
(11 genes in 8 species)
specific family
Orthologous gene family
ORTHO03P039962
(3 genes in 3 species)
specific family

Descriptions

gene_descr
Wiskott-Aldrich syndrome homolog (human)

Identifiers

Type Value
UniprotP70315
UniprotQ53WY0
MGI105059

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002625
ISO
IEA
Genome Projectregulation of T cell antigen processing and presentation
GO:0006955
ISO
IEA
Genome Projectimmune response
GO:0007015
IEA
Genome Projectactin filament organization
GO:0008154
IDA
Genome Projectactin polymerization or depolymerization
GO:0016197
IDA
Genome Projectendosomal transport
GO:0030041
IDA
Genome Projectactin filament polymerization
GO:0030048
IDA
Genome Projectactin filament-based movement
GO:0042110
IMP
Genome ProjectT cell activation
GO:2000146
ISO
IEA
Genome Projectnegative regulation of cell motility
GO:2000601
IEA
Genome Projectpositive regulation of Arp2/3 complex-mediated actin nucleation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003779
IEA
Genome Projectactin binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0017124
ISO
IEA
Genome ProjectSH3 domain binding
GO:0019901
ISO
IEA
Genome Projectprotein kinase binding
GO:0042802
IDA
ISO
IEA
Genome Projectidentical protein binding
GO:0043274
ISO
IEA
Genome Projectphospholipase binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005829
TAS
Genome Projectcytosol
GO:0005856
IEA
Genome Projectcytoskeleton
GO:0005911
IDA
Genome Projectcell-cell junction
GO:0012506
IDA
Genome Projectvesicle membrane
GO:0070062
ISO
IEA
Genome Projectextracellular exosome
GO:0005622
IDA
Genome Projectintracellular

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000095CRIB domain
IPR000697WH1/EVH1 domain
IPR003124WH2 domain
IPR011026Wiscott-Aldrich syndrome protein, C-terminal
IPR011993PH domain-like
IPR027641Wiskott-Aldrich syndrome protein

No MapMan annotations defined for this gene.