Gene: ENSMUSG00000031161 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000031161
Transcript Identifier
ENSMUST00000033501
Gene Type
Coding gene
Location
X : 7930469-7947214 : negative

Family Information

Homologous gene family
HOM03P000083
(314 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P004416
(19 genes in 16 species)
specific family

Descriptions

gene_descr
histone deacetylase 6

Identifiers

Type Value
UniprotQ9Z2V5
MGI1333752

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000209
IDA
Genome Projectprotein polyubiquitination
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006476
IDA
ISO
IEA
Genome Projectprotein deacetylation
GO:0006511
IMP, IGI
Genome Projectubiquitin-dependent protein catabolic process
GO:0006515
ISO
IEA
Genome Projectmisfolded or incompletely synthesized protein catabolic process
GO:0006886
ISO
IEA
Genome Projectintracellular protein transport
GO:0007026
IDA
Genome Projectnegative regulation of microtubule depolymerization
GO:0009636
ISO
IEA
Genome Projectresponse to toxic substance
GO:0009967
ISO
IEA
Genome Projectpositive regulation of signal transduction
GO:0010033
ISO
IEA
Genome Projectresponse to organic substance
GO:0010469
ISO
IEA
Genome Projectregulation of receptor activity
GO:0010634
ISO
IEA
Genome Projectpositive regulation of epithelial cell migration
GO:0010870
ISO
IEA
Genome Projectpositive regulation of receptor biosynthetic process
GO:0016236
ISO
IEA
Genome Projectmacroautophagy
GO:0016568
IEA
Genome Projectchromatin modification
GO:0016575
ISO
IEA
Genome Projecthistone deacetylation
GO:0031647
ISO
Genome Projectregulation of protein stability
GO:0032418
ISO
IEA
Genome Projectlysosome localization
GO:0034983
ISO
IEA
Genome Projectpeptidyl-lysine deacetylation
GO:0035967
ISO
IEA
Genome Projectcellular response to topologically incorrect protein
GO:0040029
ISO
IEA
Genome Projectregulation of gene expression, epigenetic
GO:0043162
IMP
Genome Projectubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
GO:0043241
IGI
Genome Projectprotein complex disassembly
GO:0043242
ISO
IEA
Genome Projectnegative regulation of protein complex disassembly
GO:0045598
IMP
Genome Projectregulation of fat cell differentiation
GO:0045861
ISO
IEA
Genome Projectnegative regulation of proteolysis
GO:0051646
IMP
Genome Projectmitochondrion localization
GO:0051788
ISO
IEA
Genome Projectresponse to misfolded protein
GO:0070201
IMP
Genome Projectregulation of establishment of protein localization
GO:0070301
ISO
IEA
Genome Projectcellular response to hydrogen peroxide
GO:0070842
IGI
ISO
IEA
Genome Projectaggresome assembly
GO:0070845
ISO
IEA
Genome Projectpolyubiquitinated misfolded protein transport
GO:0070846
IMP
ISO
IEA
Genome ProjectHsp90 deacetylation
GO:0070848
ISO
IEA
Genome Projectresponse to growth factor
GO:0070932
IEA
Genome Projecthistone H3 deacetylation
GO:0071218
IMP
Genome Projectcellular response to misfolded protein
GO:0090035
ISO
IEA
Genome Projectpositive regulation of chaperone-mediated protein complex assembly
GO:0090042
IDA, IMP
ISO
Genome Projecttubulin deacetylation
GO:0098779
IGI
ISO
Genome Projectmitophagy in response to mitochondrial depolarization
GO:1901300
ISO
IEA
Genome Projectpositive regulation of hydrogen peroxide-mediated programmed cell death

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001047
ISO
IEA
Genome Projectcore promoter binding
GO:0003779
IEA
Genome Projectactin binding
GO:0004407
IDA
ISO
IEA
Genome Projecthistone deacetylase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008013
ISO
IEA
Genome Projectbeta-catenin binding
GO:0008017
IDA
ISO
Genome Projectmicrotubule binding
GO:0008270
IEA
Genome Projectzinc ion binding
GO:0016787
IEA
Genome Projecthydrolase activity
GO:0031593
ISO
IEA
Genome Projectpolyubiquitin binding
GO:0031625
ISO
IEA
Genome Projectubiquitin protein ligase binding
GO:0032041
IEA
Genome ProjectNAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0042826
ISO
IEA
Genome Projecthistone deacetylase binding
GO:0042903
IDA
ISO
Genome Projecttubulin deacetylase activity
GO:0043014
ISO
IEA
Genome Projectalpha-tubulin binding
GO:0043130
IDA
Genome Projectubiquitin binding
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0048156
ISO
IEA
Genome Projecttau protein binding
GO:0048487
IDA
Genome Projectbeta-tubulin binding
GO:0051787
ISO
IEA
Genome Projectmisfolded protein binding
GO:0051879
ISO
IEA
Genome ProjectHsp90 protein binding
GO:0070840
ISO
IEA
Genome Projectdynein complex binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000118
ISO
IEA
Genome Projecthistone deacetylase complex
GO:0005634
IDA
TAS, IEA
Genome Projectnucleus
GO:0005654
ISO
IEA
Genome Projectnucleoplasm
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0005829
IDA
Genome Projectcytosol
GO:0005874
ISO
IEA
Genome Projectmicrotubule
GO:0005875
ISO
IEA
Genome Projectmicrotubule associated complex
GO:0005901
ISO
IEA
Genome Projectcaveola
GO:0016234
ISO
IEA
Genome Projectinclusion body
GO:0016235
ISO
IEA
Genome Projectaggresome
GO:0030286
ISO
IEA
Genome Projectdynein complex
GO:0030424
IDA
IEA
Genome Projectaxon
GO:0030425
IDA
IEA
Genome Projectdendrite
GO:0031252
ISO
IEA
Genome Projectcell leading edge
GO:0042995
IEA
Genome Projectcell projection
GO:0043204
IDA
IEA
Genome Projectperikaryon
GO:0043234
IPI
Genome Projectprotein complex
GO:0048471
ISO
IEA
Genome Projectperinuclear region of cytoplasm
GO:0005881
IDA
Genome Projectcytoplasmic microtubule

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000286Histone deacetylase superfamily
IPR001607Zinc finger, UBP-type
IPR013083Zinc finger, RING/FYVE/PHD-type
IPR023801Histone deacetylase domain

No MapMan annotations defined for this gene.