Gene: ENSMUSG00000031078 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000031078
Transcript Identifier
ENSMUST00000103079
Gene Type
Coding gene
Location
7 : 144436965-144463998 : negative

Family Information

Homologous gene family
HOM03P018265
(4 genes in 4 species)
specific family

Descriptions

gene_descr
cortactin

Identifiers

Type Value
UniprotQ60598
MGI99695

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006886
IMP
ISS, ISO
IEA
Genome Projectintracellular protein transport
GO:0006897
IEA
Genome Projectendocytosis
GO:0006898
ISS
Genome Projectreceptor-mediated endocytosis
GO:0006930
IGI
Genome Projectsubstrate-dependent cell migration, cell extension
GO:0030041
IEA
Genome Projectactin filament polymerization
GO:0030516
ISS
Genome Projectregulation of axon extension
GO:0030838
ISS, ISO
Genome Projectpositive regulation of actin filament polymerization
GO:0031532
ISS
Genome Projectactin cytoskeleton reorganization
GO:0045987
ISO
Genome Projectpositive regulation of smooth muscle contraction
GO:0048041
ISS
Genome Projectfocal adhesion assembly
GO:0048812
ISS
Genome Projectneuron projection morphogenesis
GO:0048870
ISS
Genome Projectcell motility
GO:0097062
IGI
Genome Projectdendritic spine maintenance
GO:0097581
ISS
Genome Projectlamellipodium organization
GO:1903146
IMP
Genome Projectregulation of mitophagy
GO:2001237
IGI
Genome Projectnegative regulation of extrinsic apoptotic signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005515
IPI
Genome Projectprotein binding
GO:0005522
ISO
Genome Projectprofilin binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001726
IDA
IEA
Genome Projectruffle
GO:0002102
IEA
Genome Projectpodosome
GO:0005737
IDA
ISO
IEA
Genome Projectcytoplasm
GO:0005829
TAS
Genome Projectcytosol
GO:0005856
IEA
Genome Projectcytoskeleton
GO:0005884
ISS, ISO
IEA
Genome Projectactin filament
GO:0005886
IEA
Genome Projectplasma membrane
GO:0005905
ISS
IEA
Genome Projectcoated pit
GO:0005925
ISS, ISO
IEA
Genome Projectfocal adhesion
GO:0005938
IDA
ISO
IEA
Genome Projectcell cortex
GO:0008076
IDA
ISO
IEA
Genome Projectvoltage-gated potassium channel complex
GO:0016020
IEA
Genome Projectmembrane
GO:0030027
IDA
ISO
IEA
Genome Projectlamellipodium
GO:0030054
ISS
IEA
Genome Projectcell junction
GO:0030425
IEA
Genome Projectdendrite
GO:0030863
ISS, ISO
IEA
Genome Projectcortical cytoskeleton
GO:0042995
IEA
Genome Projectcell projection
GO:0043197
IEA
Genome Projectdendritic spine
GO:0070062
ISO
IEA
Genome Projectextracellular exosome
GO:1990023
IDA
Genome Projectmitotic spindle midzone
GO:0030426
ISS
Genome Projectgrowth cone

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001452SH3 domain
IPR003134Hs1/Cortactin
IPR015503Cortactin

No MapMan annotations defined for this gene.