Gene: ENSMUSG00000031077 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000031077
Transcript Identifier
ENSMUST00000033394
Gene Type
Coding gene
Location
7 : 144580529-144582389 : negative

Family Information

Homologous gene family
HOM03P037259
(2 genes in 2 species)
specific family

Descriptions

gene_descr
Fas (TNFRSF6)-associated via death domain

Identifiers

Type Value
UniprotQ61160
MGI109324

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001916
IMP
Genome Projectpositive regulation of T cell mediated cytotoxicity
GO:0002376
IEA
Genome Projectimmune system process
GO:0002821
IMP
Genome Projectpositive regulation of adaptive immune response
GO:0006915
ISS, ISO
IEA
Genome Projectapoptotic process
GO:0007165
IEA
Genome Projectsignal transduction
GO:0030217
TAS
Genome ProjectT cell differentiation
GO:0032729
IMP
Genome Projectpositive regulation of interferon-gamma production
GO:0032757
ISO
IEA
Genome Projectpositive regulation of interleukin-8 production
GO:0032760
ISO
IEA
Genome Projectpositive regulation of tumor necrosis factor production
GO:0033077
IMP
Genome ProjectT cell differentiation in thymus
GO:0036462
ISO
IEA
Genome ProjectTRAIL-activated apoptotic signaling pathway
GO:0042104
IMP
Genome Projectpositive regulation of activated T cell proliferation
GO:0042981
IEA
Genome Projectregulation of apoptotic process
GO:0043029
IMP
Genome ProjectT cell homeostasis
GO:0043065
ISO
IEA
Genome Projectpositive regulation of apoptotic process
GO:0043123
IEA
Genome Projectpositive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045087
TAS, IEA
Genome Projectinnate immune response
GO:0045651
ISO
IEA
Genome Projectpositive regulation of macrophage differentiation
GO:0045862
ISO
IEA
Genome Projectpositive regulation of proteolysis
GO:0045944
ISO
IEA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0048535
IGI
Genome Projectlymph node development
GO:0048536
IGI
Genome Projectspleen development
GO:0048538
IGI
Genome Projectthymus development
GO:0048738
TAS
Genome Projectcardiac muscle tissue development
GO:0051291
IEA
Genome Projectprotein heterooligomerization
GO:0051607
ISO
IEA
Genome Projectdefense response to virus
GO:0060340
ISO
IEA
Genome Projectpositive regulation of type I interferon-mediated signaling pathway
GO:0060546
IGI
Genome Projectnegative regulation of necroptotic process
GO:0070236
IMP
Genome Projectnegative regulation of activation-induced cell death of T cells
GO:0071260
IEA
Genome Projectcellular response to mechanical stimulus
GO:0097049
IMP
Genome Projectmotor neuron apoptotic process
GO:0097190
ISO
IEA
Genome Projectapoptotic signaling pathway
GO:0097191
IDA
ISO
IEA
Genome Projectextrinsic apoptotic signaling pathway
GO:0097192
IMP
Genome Projectextrinsic apoptotic signaling pathway in absence of ligand
GO:0097202
ISO
IEA
Genome Projectactivation of cysteine-type endopeptidase activity
GO:0097527
ISO
IEA
Genome Projectnecroptotic signaling pathway
GO:1902043
IGI
Genome Projectpositive regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:2000454
IMP
Genome Projectpositive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation
GO:2001238
IGI
ISO
IEA
Genome Projectpositive regulation of extrinsic apoptotic signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002020
ISO
IEA
Genome Projectprotease binding
GO:0005123
IEA
Genome Projectdeath receptor binding
GO:0005164
IEA
Genome Projecttumor necrosis factor receptor binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0032403
IEA
Genome Projectprotein complex binding
GO:0032813
ISO
IEA
Genome Projecttumor necrosis factor receptor superfamily binding
GO:0035877
ISO
IEA
Genome Projectdeath effector domain binding
GO:0042802
ISO
IEA
Genome Projectidentical protein binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005829
ISO
IEA
Genome Projectcytosol
GO:0031264
ISO
IEA
Genome Projectdeath-inducing signaling complex
GO:0031265
ISO
IEA
Genome ProjectCD95 death-inducing signaling complex
GO:0043005
IEA
Genome Projectneuron projection
GO:0043234
IEA
Genome Projectprotein complex
GO:0044297
IEA
Genome Projectcell body
GO:0045121
IEA
Genome Projectmembrane raft
GO:0097342
ISS, ISO
IEA
Genome Projectripoptosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000488Death domain
IPR001875Death effector domain
IPR011029Death-like domain
IPR016729FADD

No MapMan annotations defined for this gene.