Gene: ENSMUSG00000030830 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000030830
Transcript Identifier
ENSMUST00000120857
Gene Type
Coding gene
Location
7 : 127296469-127330518 : positive

Family Information

Homologous gene family
HOM03P002672
(35 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P074902
(2 genes in 2 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
integrin alpha L

Identifiers

Type Value
UniprotD3Z627
MGI96606

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002291
ISO
Genome ProjectT cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
GO:0007155
IEA
Genome Projectcell adhesion
GO:0007157
ISO
Genome Projectheterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0007159
IDA, IMP
ISO
Genome Projectleukocyte cell-cell adhesion
GO:0007160
ISO
Genome Projectcell-matrix adhesion
GO:0007166
IDA
Genome Projectcell surface receptor signaling pathway
GO:0007229
IEA
Genome Projectintegrin-mediated signaling pathway
GO:0022407
IDA
Genome Projectregulation of cell-cell adhesion
GO:0022409
IMP
Genome Projectpositive regulation of cell-cell adhesion
GO:0042102
IMP
Genome Projectpositive regulation of T cell proliferation
GO:0043113
ISO
Genome Projectreceptor clustering
GO:0050798
IMP
Genome Projectactivated T cell proliferation
GO:0050850
IDA
Genome Projectpositive regulation of calcium-mediated signaling

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0030369
ISO
Genome ProjectICAM-3 receptor activity
GO:0050839
ISO
Genome Projectcell adhesion molecule binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001772
IDA
Genome Projectimmunological synapse
GO:0005911
IDA
Genome Projectcell-cell junction
GO:0008305
IEA
Genome Projectintegrin complex
GO:0009897
IDA
Genome Projectexternal side of plasma membrane
GO:0009986
ISO
Genome Projectcell surface
GO:0016020
ISO
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0034687
ISO
Genome Projectintegrin alphaL-beta2 complex
GO:0070062
ISO
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000413Integrin alpha chain
IPR002035von Willebrand factor, type A
IPR013517FG-GAP repeat
IPR013519Integrin alpha beta-propellor
IPR013649Integrin alpha-2

No MapMan annotations defined for this gene.