Gene: ENSMUSG00000030793 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000030793
Transcript Identifier
ENSMUST00000033056
Gene Type
Coding gene
Location
7 : 127992712-127993653 : negative

Family Information

Homologous gene family
HOM03P041300
(2 genes in 2 species)
specific family

Descriptions

gene_descr
PYD and CARD domain containing

Identifiers

Type Value
UniprotQ9EPB4
UniprotQ54AA2
MGI1931465

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001773
ISO
IEA
Genome Projectmyeloid dendritic cell activation
GO:0002218
IMP
ISO
IEA
Genome Projectactivation of innate immune response
GO:0002821
ISO
IEA
Genome Projectpositive regulation of adaptive immune response
GO:0006915
ISO
IEA
Genome Projectapoptotic process
GO:0006919
IMP
Genome Projectactivation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006954
IMP
IEA
Genome Projectinflammatory response
GO:0009617
IMP
Genome Projectresponse to bacterium
GO:0010506
IMP
Genome Projectregulation of autophagy
GO:0010803
ISO
IEA
Genome Projectregulation of tumor necrosis factor-mediated signaling pathway
GO:0032088
ISO
IEA
Genome Projectnegative regulation of NF-kappaB transcription factor activity
GO:0032611
IGI
Genome Projectinterleukin-1 beta production
GO:0032688
ISO
IEA
Genome Projectnegative regulation of interferon-beta production
GO:0032760
ISO
IEA
Genome Projectpositive regulation of tumor necrosis factor production
GO:0033209
ISO
IEA
Genome Projecttumor necrosis factor-mediated signaling pathway
GO:0042771
ISO
IEA
Genome Projectintrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0042981
IMP
IEA
Genome Projectregulation of apoptotic process
GO:0043065
ISO
IEA
Genome Projectpositive regulation of apoptotic process
GO:0043124
ISO
IEA
Genome Projectnegative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043280
ISS, ISO
IEA
Genome Projectpositive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043281
IMP
Genome Projectregulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0046330
ISO
IEA
Genome Projectpositive regulation of JNK cascade
GO:0050718
IMP, IGI
ISS, ISO
IEA
Genome Projectpositive regulation of interleukin-1 beta secretion
GO:0050727
IMP
Genome Projectregulation of inflammatory response
GO:0050829
ISO
IEA
Genome Projectdefense response to Gram-negative bacterium
GO:0050870
ISO
IEA
Genome Projectpositive regulation of T cell activation
GO:0051091
ISO
IEA
Genome Projectpositive regulation of sequence-specific DNA binding transcription factor activity
GO:0051092
ISO
IEA
Genome Projectpositive regulation of NF-kappaB transcription factor activity
GO:0051607
ISO
IEA
Genome Projectdefense response to virus
GO:0070374
IMP
ISO
IEA
Genome Projectpositive regulation of ERK1 and ERK2 cascade
GO:0071222
ISO
IEA
Genome Projectcellular response to lipopolysaccharide
GO:0071347
ISO
IEA
Genome Projectcellular response to interleukin-1
GO:0071356
ISO
IEA
Genome Projectcellular response to tumor necrosis factor
GO:0071901
ISO
IEA
Genome Projectnegative regulation of protein serine/threonine kinase activity
GO:0072332
ISO
IEA
Genome Projectintrinsic apoptotic signaling pathway by p53 class mediator
GO:0090197
IMP
ISO
IEA
Genome Projectpositive regulation of chemokine secretion
GO:0090200
ISO
IEA
Genome Projectpositive regulation of release of cytochrome c from mitochondria
GO:2000484
ISO
IEA
Genome Projectpositive regulation of interleukin-8 secretion
GO:2000778
ISO
IEA
Genome Projectpositive regulation of interleukin-6 secretion
GO:2001056
ISO
IEA
Genome Projectpositive regulation of cysteine-type endopeptidase activity
GO:2001181
ISO
IEA
Genome Projectpositive regulation of interleukin-10 secretion
GO:2001238
ISO
IEA
Genome Projectpositive regulation of extrinsic apoptotic signaling pathway
GO:2001242
ISO
IEA
Genome Projectregulation of intrinsic apoptotic signaling pathway
GO:0002230
IMP
Genome Projectpositive regulation of defense response to virus by host
GO:0002277
IMP
Genome Projectmyeloid dendritic cell activation involved in immune response
GO:0002376
IEA
Genome Projectimmune system process
GO:0002588
IMP
Genome Projectpositive regulation of antigen processing and presentation of peptide antigen via MHC class II
GO:0030838
IMP
Genome Projectpositive regulation of actin filament polymerization
GO:0031647
IMP
Genome Projectregulation of protein stability
GO:0032729
IMP
Genome Projectpositive regulation of interferon-gamma production
GO:0032755
IMP
Genome Projectpositive regulation of interleukin-6 production
GO:0042104
IMP
Genome Projectpositive regulation of activated T cell proliferation
GO:0043087
IMP
Genome Projectregulation of GTPase activity
GO:0044351
IMP
Genome Projectmacropinocytosis
GO:0045087
IEA
Genome Projectinnate immune response
GO:0050766
IMP
Genome Projectpositive regulation of phagocytosis
GO:0097202
IMP
Genome Projectactivation of cysteine-type endopeptidase activity
GO:2000406
IMP
Genome Projectpositive regulation of T cell migration

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002020
ISO
Genome Projectprotease binding
GO:0005138
ISO
Genome Projectinterleukin-6 receptor binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0005523
ISO
Genome Projecttropomyosin binding
GO:0016505
ISO
Genome Projectpeptidase activator activity involved in apoptotic process
GO:0017024
ISO
Genome Projectmyosin I binding
GO:0019899
ISO
Genome Projectenzyme binding
GO:0032090
ISS, ISO
IEA
Genome ProjectPyrin domain binding
GO:0042802
ISO
Genome Projectidentical protein binding
GO:0042803
ISS, ISO
IEA
Genome Projectprotein homodimerization activity
GO:0070700
ISO
Genome ProjectBMP receptor binding
GO:0046983
IMP
Genome Projectprotein dimerization activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
IDA
Genome Projectextracellular region
GO:0005634
IDA
ISO
IEA
Genome Projectnucleus
GO:0005730
ISO
IEA
Genome Projectnucleolus
GO:0005737
ISS, ISO
IEA
Genome Projectcytoplasm
GO:0005739
ISO
IEA
Genome Projectmitochondrion
GO:0005829
IDA
TAS
Genome Projectcytosol
GO:0072558
ISO
IEA
Genome ProjectNLRP1 inflammasome complex
GO:0072559
ISS, ISO
IEA
Genome ProjectNLRP3 inflammasome complex
GO:0097169
ISS, ISO
IEA
Genome ProjectAIM2 inflammasome complex
GO:0008385
ISO
Genome ProjectIkappaB kinase complex
GO:0005783
IEA
Genome Projectendoplasmic reticulum

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001315CARD domain
IPR004020DAPIN domain
IPR011029Death-like domain

No MapMan annotations defined for this gene.