Gene: ENSMUSG00000030742 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000030742
Transcript Identifier
ENSMUST00000032997
Gene Type
Coding gene
Location
7 : 126364203-126369250 : negative

Family Information

Homologous gene family
HOM03P044524
(2 genes in 2 species)
specific family

Descriptions

gene_descr
linker for activation of T cells

Identifiers

Type Value
UniprotO54957
UniprotQ546H1
MGI1342293

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002250
IEA
Genome Projectadaptive immune response
GO:0002260
IMP
Genome Projectlymphocyte homeostasis
GO:0002376
IEA
Genome Projectimmune system process
GO:0006954
IMP
Genome Projectinflammatory response
GO:0006955
ISS, ISO
IEA
Genome Projectimmune response
GO:0006968
TAS
Genome Projectcellular defense response
GO:0007165
IEA
Genome Projectsignal transduction
GO:0007169
TAS
Genome Projecttransmembrane receptor protein tyrosine kinase signaling pathway
GO:0007229
ISS, ISO
IEA
Genome Projectintegrin-mediated signaling pathway
GO:0007265
ISS, ISO
IEA
Genome ProjectRas protein signal transduction
GO:0009967
ISO
IEA
Genome Projectpositive regulation of signal transduction
GO:0010467
IMP
Genome Projectgene expression
GO:0019722
ISS, ISO
IEA
Genome Projectcalcium-mediated signaling
GO:0035556
ISS, ISO
IEA
Genome Projectintracellular signal transduction
GO:0043303
IEA
Genome Projectmast cell degranulation
GO:0045860
IEA
Genome Projectpositive regulation of protein kinase activity
GO:0048872
IMP
Genome Projecthomeostasis of number of cells
GO:0050863
ISS, ISO
IEA
Genome Projectregulation of T cell activation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005057
TAS
Genome Projectreceptor signaling protein activity
GO:0005070
ISS, ISO
IEA
Genome ProjectSH3/SH2 adaptor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0019901
ISO
IEA
Genome Projectprotein kinase binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001772
IDA
ISO
IEA
Genome Projectimmunological synapse
GO:0005886
IEA
Genome Projectplasma membrane
GO:0005887
TAS
Genome Projectintegral component of plasma membrane
GO:0005911
IDA
Genome Projectcell-cell junction
GO:0008180
IDA
Genome ProjectCOP9 signalosome
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
ISO
IEA
Genome Projectintegral component of membrane
GO:0042629
IEA
Genome Projectmast cell granule
GO:0005622
ISO
IEA
Genome Projectintracellular

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR008359Linker-for-activation of T cells (LAT) protein

No MapMan annotations defined for this gene.