Gene: ENSMUSG00000030525 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000030525
Transcript Identifier
ENSMUST00000032738
Gene Type
Coding gene
Location
7 : 63099224-63212476 : negative

Family Information

Homologous gene family
HOM03P000517
(94 genes in 7 species)
specific family
Orthologous gene family
ORTHO03P007409
(11 genes in 4 species)
specific family

Descriptions

gene_descr
cholinergic receptor, nicotinic, alpha polypeptide 7

Identifiers

Type Value
UniprotP49582
UniprotQ53YJ9
MGI99779

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000187
ISO
Genome Projectactivation of MAPK activity
GO:0001666
ISO
Genome Projectresponse to hypoxia
GO:0001988
IMP
Genome Projectpositive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure
GO:0006810
IEA
Genome Projecttransport
GO:0006811
IMP
IEA
Genome Projection transport
GO:0006816
ISO
IEA
Genome Projectcalcium ion transport
GO:0006874
ISO
Genome Projectcellular calcium ion homeostasis
GO:0006897
IMP
Genome Projectendocytosis
GO:0007165
ISO
Genome Projectsignal transduction
GO:0007271
IMP
IEA
Genome Projectsynaptic transmission, cholinergic
GO:0007613
IMP
Genome Projectmemory
GO:0008284
ISO
Genome Projectpositive regulation of cell proliferation
GO:0008306
IMP, IGI
Genome Projectassociative learning
GO:0014061
IMP
Genome Projectregulation of norepinephrine secretion
GO:0019228
IEA
Genome Projectneuronal action potential
GO:0030317
IMP
Genome Projectsperm motility
GO:0032094
IMP
Genome Projectresponse to food
GO:0032225
IMP
Genome Projectregulation of synaptic transmission, dopaminergic
GO:0032691
IMP
Genome Projectnegative regulation of interleukin-1 beta production
GO:0032715
IMP
Genome Projectnegative regulation of interleukin-6 production
GO:0032720
IMP
ISO
Genome Projectnegative regulation of tumor necrosis factor production
GO:0034220
ISO
IEA
Genome Projection transmembrane transport
GO:0035094
IMP
ISO
Genome Projectresponse to nicotine
GO:0035095
IGI
Genome Projectbehavioral response to nicotine
GO:0042110
IMP
Genome ProjectT cell activation
GO:0042113
IMP
Genome ProjectB cell activation
GO:0042391
IMP
ISO
IEA
Genome Projectregulation of membrane potential
GO:0042416
IEA
Genome Projectdopamine biosynthetic process
GO:0042698
IMP
Genome Projectovulation cycle
GO:0045471
IMP
Genome Projectresponse to ethanol
GO:0045766
ISO
Genome Projectpositive regulation of angiogenesis
GO:0048149
IMP
Genome Projectbehavioral response to ethanol
GO:0050727
IMP
Genome Projectregulation of inflammatory response
GO:0050728
IMP
Genome Projectnegative regulation of inflammatory response
GO:0050890
ISO
Genome Projectcognition
GO:0060112
IMP
Genome Projectgeneration of ovulation cycle rhythm
GO:0098655
ISO
IEA
Genome Projectcation transmembrane transport

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001540
ISO
Genome Projectbeta-amyloid binding
GO:0004889
IDA, IMP
ISO
IEA
Genome Projectacetylcholine-activated cation-selective channel activity
GO:0005216
IEA
Genome Projection channel activity
GO:0005230
IEA
Genome Projectextracellular ligand-gated ion channel activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008144
IEA
Genome Projectdrug binding
GO:0008179
IEA
Genome Projectadenylate cyclase binding
GO:0015464
ISO
Genome Projectacetylcholine receptor activity
GO:0015643
ISO
Genome Projecttoxic substance binding
GO:0017081
ISO
Genome Projectchloride channel regulator activity
GO:0019901
IEA
Genome Projectprotein kinase binding
GO:0022848
ISO
Genome Projectacetylcholine-gated cation channel activity
GO:0042166
ISO
IEA
Genome Projectacetylcholine binding
GO:0042803
ISO
Genome Projectprotein homodimerization activity
GO:0051117
IEA
Genome ProjectATPase binding
GO:0097110
IEA
Genome Projectscaffold protein binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005886
ISO
IEA
Genome Projectplasma membrane
GO:0005892
ISO
IEA
Genome Projectacetylcholine-gated channel complex
GO:0009897
IDA
Genome Projectexternal side of plasma membrane
GO:0014069
IEA
Genome Projectpostsynaptic density
GO:0016020
IDA
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0016324
IDA
Genome Projectapical plasma membrane
GO:0030054
IEA
Genome Projectcell junction
GO:0030424
IEA
Genome Projectaxon
GO:0030425
IEA
Genome Projectdendrite
GO:0030426
IEA
Genome Projectgrowth cone
GO:0030673
IDA
Genome Projectaxolemma
GO:0032279
IEA
Genome Projectasymmetric synapse
GO:0042734
IEA
Genome Projectpresynaptic membrane
GO:0043025
IEA
Genome Projectneuronal cell body
GO:0043197
IEA
Genome Projectdendritic spine
GO:0043198
IEA
Genome Projectdendritic shaft
GO:0045121
IEA
Genome Projectmembrane raft
GO:0045202
IEA
Genome Projectsynapse
GO:0045211
IEA
Genome Projectpostsynaptic membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR002394Nicotinic acetylcholine receptor
IPR006029Neurotransmitter-gated ion-channel transmembrane domain
IPR006201Neurotransmitter-gated ion-channel
IPR006202Neurotransmitter-gated ion-channel ligand-binding domain
IPR018000Neurotransmitter-gated ion-channel, conserved site
IPR027361Nicotinic acetylcholine-gated receptor, transmembrane domain

No MapMan annotations defined for this gene.