Gene: ENSMUSG00000030111 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000030111
Transcript Identifier
ENSMUST00000032203
Gene Type
Coding gene
Location
6 : 121636289-121679108 : positive

Family Information

Homologous gene family
HOM03P002669
(35 genes in 6 species)
specific family
Orthologous gene family
ORTHO03P008834
(9 genes in 2 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
alpha-2-macroglobulin

Identifiers

Type Value
UniprotQ6GQT1
MGI2449119

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001869
ISO
IEA
Genome Projectnegative regulation of complement activation, lectin pathway
GO:0007565
IEA
Genome Projectfemale pregnancy
GO:0010466
IEA
Genome Projectnegative regulation of peptidase activity
GO:0010951
ISO
Genome Projectnegative regulation of endopeptidase activity
GO:0048863
IDA
Genome Projectstem cell differentiation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002020
ISO
IEA
Genome Projectprotease binding
GO:0004866
IEA
Genome Projectendopeptidase inhibitor activity
GO:0004867
ISO
IEA
Genome Projectserine-type endopeptidase inhibitor activity
GO:0005102
ISO
IEA
Genome Projectreceptor binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0019838
ISO
IEA
Genome Projectgrowth factor binding
GO:0019899
ISO
IEA
Genome Projectenzyme binding
GO:0019959
ISO
IEA
Genome Projectinterleukin-8 binding
GO:0019966
ISO
IEA
Genome Projectinterleukin-1 binding
GO:0030414
TAS, IEA
Genome Projectpeptidase inhibitor activity
GO:0043120
ISO
IEA
Genome Projecttumor necrosis factor binding
GO:0048306
ISO
IEA
Genome Projectcalcium-dependent protein binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
IEA
Genome Projectextracellular region
GO:0005615
IEA
Genome Projectextracellular space
GO:0070062
ISO
IEA
Genome Projectextracellular exosome
GO:0072562
ISO
IEA
Genome Projectblood microparticle

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001599Alpha-2-macroglobulin
IPR002890Alpha-2-macroglobulin, N-terminal
IPR008930Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid
IPR009048Alpha-macroglobulin, receptor-binding
IPR011625Alpha-2-macroglobulin, N-terminal 2
IPR011626Alpha-macroglobulin complement component
IPR014756Immunoglobulin E-set
IPR019565Alpha-2-macroglobulin, thiol-ester bond-forming
IPR019742Alpha-2-macroglobulin, conserved site

No MapMan annotations defined for this gene.