Gene: ENSMUSG00000030110 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000030110
Transcript Identifier
ENSMUST00000032201
Gene Type
Coding gene
Location
6 : 118153853-118197133 : negative

Family Information

Homologous gene family
HOM03P000004
(1817 genes in 37 species)
specific family
Orthologous gene family
ORTHO03P040742
(3 genes in 3 species)
specific family
Duplication type
Tandem duplicate   and   Block duplicate

Descriptions

gene_descr
ret proto-oncogene

Identifiers

Type Value
UniprotP35546
MGI97902

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000165
IGI
Genome ProjectMAPK cascade
GO:0001657
IMP
Genome Projectureteric bud development
GO:0001755
IMP
Genome Projectneural crest cell migration
GO:0001838
IDA, IGI
Genome Projectembryonic epithelial tube formation
GO:0006468
IEA
Genome Projectprotein phosphorylation
GO:0006919
ISO
IEA
Genome Projectactivation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007155
IEA
Genome Projectcell adhesion
GO:0007156
IEA
Genome Projecthomophilic cell adhesion via plasma membrane adhesion molecules
GO:0007158
IDA
ISO
IEA
Genome Projectneuron cell-cell adhesion
GO:0007169
IGI
Genome Projecttransmembrane receptor protein tyrosine kinase signaling pathway
GO:0007399
IMP
Genome Projectnervous system development
GO:0009653
TAS
Genome Projectanatomical structure morphogenesis
GO:0010628
IMP
Genome Projectpositive regulation of gene expression
GO:0010976
ISO
IEA
Genome Projectpositive regulation of neuron projection development
GO:0014042
IEA
Genome Projectpositive regulation of neuron maturation
GO:0016310
IEA
Genome Projectphosphorylation
GO:0018108
TAS, IEA
Genome Projectpeptidyl-tyrosine phosphorylation
GO:0030155
ISO
IEA
Genome Projectregulation of cell adhesion
GO:0030182
IMP
Genome Projectneuron differentiation
GO:0030335
ISO
IEA
Genome Projectpositive regulation of cell migration
GO:0033619
ISO
IEA
Genome Projectmembrane protein proteolysis
GO:0033630
ISO
IEA
Genome Projectpositive regulation of cell adhesion mediated by integrin
GO:0035799
IMP
Genome Projectureter maturation
GO:0042493
IEA
Genome Projectresponse to drug
GO:0042551
IMP
Genome Projectneuron maturation
GO:0045793
IMP
Genome Projectpositive regulation of cell size
GO:0045893
IMP
Genome Projectpositive regulation of transcription, DNA-templated
GO:0048265
IMP
Genome Projectresponse to pain
GO:0048484
IMP
Genome Projectenteric nervous system development
GO:0050770
IMP
Genome Projectregulation of axonogenesis
GO:0060041
IEA
Genome Projectretina development in camera-type eye
GO:0060384
IEA
Genome Projectinnervation
GO:0061146
IMP
Genome ProjectPeyer's patch morphogenesis
GO:0071300
ISO
IEA
Genome Projectcellular response to retinoic acid
GO:0072300
IMP
Genome Projectpositive regulation of metanephric glomerulus development
GO:2001241
ISO
IEA
Genome Projectpositive regulation of extrinsic apoptotic signaling pathway in absence of ligand

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0004672
IEA
Genome Projectprotein kinase activity
GO:0004713
IEA
Genome Projectprotein tyrosine kinase activity
GO:0004714
TAS, IEA
Genome Projecttransmembrane receptor protein tyrosine kinase activity
GO:0005509
ISO
IEA
Genome Projectcalcium ion binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0005524
IEA
Genome ProjectATP binding
GO:0016301
IEA
Genome Projectkinase activity
GO:0016740
IEA
Genome Projecttransferase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
ISO
IEA
Genome Projectcytoplasm
GO:0005768
IEA
Genome Projectendosome
GO:0005769
IEA
Genome Projectearly endosome
GO:0005886
ISO
IEA
Genome Projectplasma membrane
GO:0005887
ISO
IEA
Genome Projectintegral component of plasma membrane
GO:0010008
ISO
IEA
Genome Projectendosome membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0030424
IEA
Genome Projectaxon
GO:0030425
IEA
Genome Projectdendrite
GO:0043025
IEA
Genome Projectneuronal cell body
GO:0043231
ISO
IEA
Genome Projectintracellular membrane-bounded organelle
GO:0043235
ISO
IEA
Genome Projectreceptor complex
GO:0045121
IEA
Genome Projectmembrane raft

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000719Protein kinase domain
IPR001245Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002126Cadherin
IPR008266Tyrosine-protein kinase, active site
IPR011009Protein kinase-like domain
IPR015919Cadherin-like
IPR016249Tyrosine-protein kinase, Ret receptor
IPR017441Protein kinase, ATP binding site
IPR020635Tyrosine-protein kinase, catalytic domain

No MapMan annotations defined for this gene.