Gene: ENSMUSG00000030102 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000030102
Transcript Identifier
ENSMUST00000032192
Gene Type
Coding gene
Location
6 : 108236994-108549839 : positive

Family Information

Homologous gene family
HOM03P001263
(54 genes in 8 species)
specific family
Orthologous gene family
ORTHO03P008296
(10 genes in 6 species)
specific family

Descriptions

gene_descr
inositol 1,4,5-trisphosphate receptor 1

Identifiers

Type Value
UniprotP11881
MGI96623

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001666
IDA
ISO
IEA
Genome Projectresponse to hypoxia
GO:0006810
IEA
Genome Projecttransport
GO:0006811
IEA
Genome Projection transport
GO:0006816
IDA
IEA
Genome Projectcalcium ion transport
GO:0006915
IEA
Genome Projectapoptotic process
GO:0009791
IMP
Genome Projectpost-embryonic development
GO:0032469
IGI
Genome Projectendoplasmic reticulum calcium ion homeostasis
GO:0042045
IDA
Genome Projectepithelial fluid transport
GO:0048016
IDA
TAS, IEA
Genome Projectinositol phosphate-mediated signaling
GO:0050849
ISO
IEA
Genome Projectnegative regulation of calcium-mediated signaling
GO:0050882
IMP
Genome Projectvoluntary musculoskeletal movement
GO:0051209
IMP
Genome Projectrelease of sequestered calcium ion into cytosol
GO:0055085
IEA
Genome Projecttransmembrane transport
GO:0070059
IMP
Genome Projectintrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0070588
IEA
Genome Projectcalcium ion transmembrane transport

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005216
IEA
Genome Projection channel activity
GO:0005218
IDA
Genome Projectintracellular ligand-gated calcium channel activity
GO:0005220
IDA
TAS, IEA
Genome Projectinositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
GO:0005262
IEA
Genome Projectcalcium channel activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0019855
ISO
IEA
Genome Projectcalcium channel inhibitor activity
GO:0035091
IDA
Genome Projectphosphatidylinositol binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005635
IDA
Genome Projectnuclear envelope
GO:0005637
IDA
Genome Projectnuclear inner membrane
GO:0005730
IDA
Genome Projectnucleolus
GO:0005737
IDA
Genome Projectcytoplasm
GO:0005783
TAS, IEA
Genome Projectendoplasmic reticulum
GO:0005789
IDA
IEA
Genome Projectendoplasmic reticulum membrane
GO:0005955
IDA
Genome Projectcalcineurin complex
GO:0014069
IDA
Genome Projectpostsynaptic density
GO:0016020
ISO
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0016529
IDA
Genome Projectsarcoplasmic reticulum
GO:0031088
ISO
IEA
Genome Projectplatelet dense granule membrane
GO:0031094
ISO
IEA
Genome Projectplatelet dense tubular network
GO:0043234
IPI
Genome Projectprotein complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000493Inositol 1,4,5-trisphosphate-binding protein receptor
IPR000699RIH (RyR and IP3R Homology) domain
IPR005821Ion transport domain
IPR013662RyR/IP3R Homology associated domain
IPR014821Inositol 1,4,5-trisphosphate/ryanodine receptor
IPR015925Ryanodine receptor-related
IPR016093MIR motif

No MapMan annotations defined for this gene.