Gene: ENSMUSG00000029863 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000029863
Transcript Identifier
ENSMUST00000031895
Gene Type
Coding gene
Location
6 : 42265124-42280477 : positive

Family Information

Homologous gene family
HOM03P003300
(30 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P075821
(2 genes in 2 species)
specific family

Descriptions

gene_descr
caspase 2

Identifiers

Type Value
UniprotP29594
MGI97295

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001554
IEA
Genome Projectluteolysis
GO:0003407
IEA
Genome Projectneural retina development
GO:0006508
RCA
IEA
Genome Projectproteolysis
GO:0006915
IBA
IEA
Genome Projectapoptotic process
GO:0006919
IBA
Genome Projectactivation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006977
ISO
IEA
Genome ProjectDNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0007420
IEA
Genome Projectbrain development
GO:0007568
IEA
Genome Projectaging
GO:0008630
IBA
Genome Projectintrinsic apoptotic signaling pathway in response to DNA damage
GO:0016485
ISO
IEA
Genome Projectprotein processing
GO:0035234
IGI
Genome Projectectopic germ cell programmed cell death
GO:0042981
IEA
Genome Projectregulation of apoptotic process
GO:0043065
ISO, ISA
IEA
Genome Projectpositive regulation of apoptotic process
GO:0043066
ISA
Genome Projectnegative regulation of apoptotic process
GO:0043525
IEA
Genome Projectpositive regulation of neuron apoptotic process
GO:0071260
IEA
Genome Projectcellular response to mechanical stimulus
GO:0097190
IDA
Genome Projectapoptotic signaling pathway
GO:0097192
IMP
Genome Projectextrinsic apoptotic signaling pathway in absence of ligand
GO:2001235
IGI
Genome Projectpositive regulation of apoptotic signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004197
ISO
IEA
Genome Projectcysteine-type endopeptidase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008233
RCA
IEA
Genome Projectpeptidase activity
GO:0008234
IEA
Genome Projectcysteine-type peptidase activity
GO:0016787
IEA
Genome Projecthydrolase activity
GO:0019904
ISO
IEA
Genome Projectprotein domain specific binding
GO:0097153
IDA
Genome Projectcysteine-type endopeptidase activity involved in apoptotic process
GO:0097199
IBA
Genome Projectcysteine-type endopeptidase activity involved in apoptotic signaling pathway

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
Genome Projectnucleus
GO:0005737
IDA
Genome Projectcytoplasm
GO:0005739
IEA
Genome Projectmitochondrion
GO:0016020
IEA
Genome Projectmembrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001309Peptidase C14, ICE, catalytic subunit p20
IPR001315CARD domain
IPR002138Peptidase C14, caspase non-catalytic subunit p10
IPR011029Death-like domain
IPR011600Peptidase C14, caspase domain
IPR015917Peptidase C14A, caspase precursor p45, core
IPR016129Peptidase C14, ICE, catalytic subunit p20, active site
IPR017350Peptidase C14A, Casp1-type
IPR029030Caspase-like domain

No MapMan annotations defined for this gene.