Gene: ENSMUSG00000029687 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000029687
Transcript Identifier
ENSMUST00000081721
Gene Type
Coding gene
Location
6 : 47530541-47577660 : negative

Family Information

Homologous gene family
HOM03P001405
(51 genes in 31 species)
specific family
Orthologous gene family
ORTHO03P001130
(40 genes in 31 species)
specific family

Descriptions

gene_descr
enhancer of zeste homolog 2 (Drosophila)

Identifiers

Type Value
UniprotQ61188
MGI107940

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
IDA
ISS, ISO
IEA
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0001932
IMP
Genome Projectregulation of protein phosphorylation
GO:0006306
IMP
Genome ProjectDNA methylation
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006357
IMP
Genome Projectregulation of transcription from RNA polymerase II promoter
GO:0010468
IMP
Genome Projectregulation of gene expression
GO:0010629
IEA
Genome Projectnegative regulation of gene expression
GO:0010718
ISS, ISO
IEA
Genome Projectpositive regulation of epithelial to mesenchymal transition
GO:0014013
IMP
Genome Projectregulation of gliogenesis
GO:0014834
IMP
Genome Projectskeletal muscle satellite cell maintenance involved in skeletal muscle regeneration
GO:0016568
IEA
Genome Projectchromatin modification
GO:0016571
IDA
Genome Projecthistone methylation
GO:0021695
IMP
Genome Projectcerebellar cortex development
GO:0021766
IEA
Genome Projecthippocampus development
GO:0032259
IEA
Genome Projectmethylation
GO:0032355
IEA
Genome Projectresponse to estradiol
GO:0034244
IMP
Genome Projectnegative regulation of transcription elongation from RNA polymerase II promoter
GO:0042127
IMP
Genome Projectregulation of cell proliferation
GO:0042752
IMP
ISO
IEA
Genome Projectregulation of circadian rhythm
GO:0043406
ISS, ISO
IEA
Genome Projectpositive regulation of MAP kinase activity
GO:0043433
IGI
Genome Projectnegative regulation of sequence-specific DNA binding transcription factor activity
GO:0043547
ISS, ISO
IEA
Genome Projectpositive regulation of GTPase activity
GO:0045605
IMP
Genome Projectnegative regulation of epidermal cell differentiation
GO:0045814
ISS, ISO
IEA
Genome Projectnegative regulation of gene expression, epigenetic
GO:0045892
ISS, ISO
IEA
Genome Projectnegative regulation of transcription, DNA-templated
GO:0048387
ISS, ISO
IEA
Genome Projectnegative regulation of retinoic acid receptor signaling pathway
GO:0048511
IEA
Genome Projectrhythmic process
GO:0050767
IMP
Genome Projectregulation of neurogenesis
GO:0051154
IDA
Genome Projectnegative regulation of striated muscle cell differentiation
GO:0070301
IDA
Genome Projectcellular response to hydrogen peroxide
GO:0070314
IMP
Genome ProjectG1 to G0 transition
GO:0070734
IMP
ISO
IEA
Genome Projecthistone H3-K27 methylation
GO:0071168
IMP
Genome Projectprotein localization to chromatin
GO:0071902
ISS, ISO
IEA
Genome Projectpositive regulation of protein serine/threonine kinase activity
GO:1900006
IEA
Genome Projectpositive regulation of dendrite development
GO:2000134
IMP
Genome Projectnegative regulation of G1/S transition of mitotic cell cycle

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000975
IEA
Genome Projectregulatory region DNA binding
GO:0001047
IDA, IMP
Genome Projectcore promoter binding
GO:0003682
IDA
ISO
IEA
Genome Projectchromatin binding
GO:0003723
IDA, IPI
Genome ProjectRNA binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0008168
IEA
Genome Projectmethyltransferase activity
GO:0016279
IDA
Genome Projectprotein-lysine N-methyltransferase activity
GO:0016740
IEA
Genome Projecttransferase activity
GO:0018024
ISO
IEA
Genome Projecthistone-lysine N-methyltransferase activity
GO:0031490
ISO
IEA
Genome Projectchromatin DNA binding
GO:0042054
IDA
ISO
IEA
Genome Projecthistone methyltransferase activity
GO:0043565
IDA
Genome Projectsequence-specific DNA binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000790
IDA
ISO
IEA
Genome Projectnuclear chromatin
GO:0005634
IDA
ISO
IEA
Genome Projectnucleus
GO:0005654
ISO
IEA
Genome Projectnucleoplasm
GO:0005694
IEA
Genome Projectchromosome
GO:0005737
ISO
IEA
Genome Projectcytoplasm
GO:0035098
IDA
ISO
IEA
Genome ProjectESC/E(Z) complex
GO:0045120
IDA
Genome Projectpronucleus

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001005SANT/Myb domain
IPR001214SET domain
IPR021654WD repeat binding protein EZH2
IPR026489CXC domain

No MapMan annotations defined for this gene.