Gene: ENSMUSG00000029528 (Mus musculus)

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Gene Identifier
ENSMUSG00000029528
Transcript Identifier
ENSMUST00000086523
Gene Type
Coding gene
Location
5 : 115506856-115554135 : positive

Family Information

Homologous gene family
HOM03P001269
(54 genes in 12 species)
specific family
Orthologous gene family
ORTHO03P011360
(8 genes in 8 species)
specific family

Descriptions

gene_descr
paxillin

Identifiers

Type Value
UniprotF8VQ28
MGI108295

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000187
IDA
Genome Projectactivation of MAPK activity
GO:0007010
IMP
Genome Projectcytoskeleton organization
GO:0007160
IEA
Genome Projectcell-matrix adhesion
GO:0007179
ISO
IEA
Genome Projecttransforming growth factor beta receptor signaling pathway
GO:0007229
IMP
TAS
Genome Projectintegrin-mediated signaling pathway
GO:0008360
IMP
Genome Projectregulation of cell shape
GO:0018108
IDA
Genome Projectpeptidyl-tyrosine phosphorylation
GO:0030032
IDA
Genome Projectlamellipodium assembly
GO:0034446
IMP
Genome Projectsubstrate adhesion-dependent cell spreading
GO:0034614
IEA
Genome Projectcellular response to reactive oxygen species
GO:0045860
IMP
Genome Projectpositive regulation of protein kinase activity
GO:0048041
IDA
Genome Projectfocal adhesion assembly
GO:0048754
IDA
Genome Projectbranching morphogenesis of an epithelial tube
GO:0060396
ISO
IEA
Genome Projectgrowth hormone receptor signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005178
IEA
Genome Projectintegrin binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0008013
ISO
IEA
Genome Projectbeta-catenin binding
GO:0008270
IEA
Genome Projectzinc ion binding
GO:0017166
ISO
IEA
Genome Projectvinculin binding
GO:0019901
IEA
Genome Projectprotein kinase binding
GO:0030159
TAS
Genome Projectreceptor signaling complex scaffold activity
GO:0032403
IEA
Genome Projectprotein complex binding
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0051435
IPI
Genome ProjectBH4 domain binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001725
ISO
IEA
Genome Projectstress fiber
GO:0005654
ISO
IEA
Genome Projectnucleoplasm
GO:0005737
ISO
IEA
Genome Projectcytoplasm
GO:0005856
IEA
Genome Projectcytoskeleton
GO:0005886
ISO
Genome Projectplasma membrane
GO:0005925
IDA
ISO
TAS, IEA
Genome Projectfocal adhesion
GO:0030027
IDA
ISO
IEA
Genome Projectlamellipodium
GO:0031252
IDA
Genome Projectcell leading edge

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001781Zinc finger, LIM-type
IPR001904Paxillin

No MapMan annotations defined for this gene.