Gene: ENSMUSG00000029468 (Mus musculus)

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Gene Identifier
ENSMUSG00000029468
Transcript Identifier
ENSMUST00000100737
Gene Type
Coding gene
Location
5 : 122644074-122681304 : positive

Family Information

Homologous gene family
HOM03P009278
(9 genes in 2 species)
specific family
Orthologous gene family
ORTHO03P068077
(2 genes in 2 species)
specific family

Descriptions

gene_descr
purinergic receptor P2X, ligand-gated ion channel, 7

Identifiers

Type Value
UniprotQ9Z1M0
UniprotQ8CHP4
MGI1339957

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000187
IMP
Genome Projectactivation of MAPK activity
GO:0000902
IMP
Genome Projectcell morphogenesis
GO:0001845
IMP
Genome Projectphagolysosome assembly
GO:0001916
IMP
Genome Projectpositive regulation of T cell mediated cytotoxicity
GO:0001934
IMP
Genome Projectpositive regulation of protein phosphorylation
GO:0006468
IMP
Genome Projectprotein phosphorylation
GO:0006509
IMP
Genome Projectmembrane protein ectodomain proteolysis
GO:0006649
IMP
Genome Projectphospholipid transfer to membrane
GO:0006810
IEA
Genome Projecttransport
GO:0006811
IEA
Genome Projection transport
GO:0006812
IMP
Genome Projectcation transport
GO:0006816
IMP
Genome Projectcalcium ion transport
GO:0006884
IDA
Genome Projectcell volume homeostasis
GO:0006900
IMP
Genome Projectmembrane budding
GO:0006954
IMP
Genome Projectinflammatory response
GO:0007005
IDA
Genome Projectmitochondrion organization
GO:0007009
IDA
Genome Projectplasma membrane organization
GO:0009612
IMP
Genome Projectresponse to mechanical stimulus
GO:0009617
IMP
Genome Projectresponse to bacterium
GO:0010033
IMP
Genome Projectresponse to organic substance
GO:0010043
IMP
Genome Projectresponse to zinc ion
GO:0010467
IMP
Genome Projectgene expression
GO:0010524
ISO
IEA
Genome Projectpositive regulation of calcium ion transport into cytosol
GO:0010628
ISO
IEA
Genome Projectpositive regulation of gene expression
GO:0012501
IDA, IMP
Genome Projectprogrammed cell death
GO:0014049
IMP
Genome Projectpositive regulation of glutamate secretion
GO:0014054
IMP
Genome Projectpositive regulation of gamma-aminobutyric acid secretion
GO:0014070
IDA
Genome Projectresponse to organic cyclic compound
GO:0016079
IMP
Genome Projectsynaptic vesicle exocytosis
GO:0016485
IMP
Genome Projectprotein processing
GO:0017121
ISO
Genome Projectphospholipid scrambling
GO:0019835
IDA, IMP
Genome Projectcytolysis
GO:0030501
IMP
Genome Projectpositive regulation of bone mineralization
GO:0031668
IMP
Genome Projectcellular response to extracellular stimulus
GO:0032060
IMP
ISO
Genome Projectbleb assembly
GO:0032308
IMP
Genome Projectpositive regulation of prostaglandin secretion
GO:0032496
IDA, IMP
Genome Projectresponse to lipopolysaccharide
GO:0032731
IMP
Genome Projectpositive regulation of interleukin-1 beta production
GO:0032755
IMP
Genome Projectpositive regulation of interleukin-6 production
GO:0032963
IMP
Genome Projectcollagen metabolic process
GO:0033198
IDA, IMP
ISO
IEA
Genome Projectresponse to ATP
GO:0034405
IMP
Genome Projectresponse to fluid shear stress
GO:0034767
ISO
Genome Projectpositive regulation of ion transmembrane transport
GO:0035590
ISO
Genome Projectpurinergic nucleotide receptor signaling pathway
GO:0042098
IMP
Genome ProjectT cell proliferation
GO:0042493
IMP
Genome Projectresponse to drug
GO:0043029
IMP
Genome ProjectT cell homeostasis
GO:0043065
IMP
Genome Projectpositive regulation of apoptotic process
GO:0043085
IMP
Genome Projectpositive regulation of catalytic activity
GO:0043132
IMP
Genome ProjectNAD transport
GO:0043409
IDA
Genome Projectnegative regulation of MAPK cascade
GO:0043410
IMP
Genome Projectpositive regulation of MAPK cascade
GO:0044254
IDA
Genome Projectmulticellular organismal protein catabolic process
GO:0045332
IDA
Genome Projectphospholipid translocation
GO:0045778
IMP
Genome Projectpositive regulation of ossification
GO:0045779
IMP
Genome Projectnegative regulation of bone resorption
GO:0045794
IMP
ISO
Genome Projectnegative regulation of cell volume
GO:0045821
ISO
IEA
Genome Projectpositive regulation of glycolytic process
GO:0046513
IDA
Genome Projectceramide biosynthetic process
GO:0046931
IMP
ISO
IEA
Genome Projectpore complex assembly
GO:0048705
IMP
Genome Projectskeletal system morphogenesis
GO:0048873
IMP
Genome Projecthomeostasis of number of cells within a tissue
GO:0050714
IDA
Genome Projectpositive regulation of protein secretion
GO:0050715
IMP
Genome Projectpositive regulation of cytokine secretion
GO:0050717
IMP
Genome Projectpositive regulation of interleukin-1 alpha secretion
GO:0050718
IMP
ISO
IEA
Genome Projectpositive regulation of interleukin-1 beta secretion
GO:0050830
IMP
Genome Projectdefense response to Gram-positive bacterium
GO:0051209
IMP
Genome Projectrelease of sequestered calcium ion into cytosol
GO:0051259
IDA
Genome Projectprotein oligomerization
GO:0051592
IDA, IMP
Genome Projectresponse to calcium ion
GO:0051602
IMP
Genome Projectresponse to electrical stimulus
GO:0051899
ISO
IEA
Genome Projectmembrane depolarization
GO:0051901
IMP
Genome Projectpositive regulation of mitochondrial depolarization
GO:0070230
IMP
Genome Projectpositive regulation of lymphocyte apoptotic process
GO:0071359
IMP
Genome Projectcellular response to dsRNA
GO:0071407
IDA
Genome Projectcellular response to organic cyclic compound
GO:0072593
IMP
Genome Projectreactive oxygen species metabolic process
GO:0097191
IMP
Genome Projectextrinsic apoptotic signaling pathway
GO:0098655
IEA
Genome Projectcation transmembrane transport
GO:1904172
ISO
Genome Projectpositive regulation of bleb assembly
GO:0019233
IMP
Genome Projectsensory perception of pain

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001530
IDA
Genome Projectlipopolysaccharide binding
GO:0001614
ISO, IBA
IEA
Genome Projectpurinergic nucleotide receptor activity
GO:0004872
IMP
Genome Projectreceptor activity
GO:0004931
IMP
ISO
IEA
Genome Projectextracellular ATP-gated cation channel activity
GO:0005216
IEA
Genome Projection channel activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005524
IMP
IEA
Genome ProjectATP binding
GO:0015267
IMP
ISO
Genome Projectchannel activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005639
IBA
Genome Projectintegral component of nuclear inner membrane
GO:0005886
IDA
ISO
IEA
Genome Projectplasma membrane
GO:0005887
IMP
ISS
IEA
Genome Projectintegral component of plasma membrane
GO:0005911
IDA
Genome Projectcell-cell junction
GO:0009897
IDA
Genome Projectexternal side of plasma membrane
GO:0016020
IDA
ISO
IEA
Genome Projectmembrane
GO:0031594
IDA
Genome Projectneuromuscular junction
GO:0043025
IDA
Genome Projectneuronal cell body
GO:0045202
IDA
Genome Projectsynapse
GO:0016021
IEA
Genome Projectintegral component of membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001429P2X purinoreceptor
IPR003050P2X7 purinoceptor
IPR027309P2X purinoreceptor extracellular domain

No MapMan annotations defined for this gene.